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- W2941279309 abstract "CMV is the most common non-genetic cause of sensorineural hearing loss (SNHL). Pathogenesis of CMV-induced SNHL is still elusive. A key role for CMV infection and loss of spiral ganglion neurons (SGNs) has been identified in a mouse model of intraperitoneal CMV inoculation. In turn, neither infection nor cell death were observed in the Organ of Corti (OC). This result is in contrast with pathology of CMV-infected human infants. Here we investigate CMV infection in the developing OC of newborn mice and the related hearing outcomes." @default.
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- W2941279309 date "2019-12-01" @default.
- W2941279309 modified "2023-09-25" @default.
- W2941279309 title "Cytomegalovirus infects the developing Organ of Corti in a mouse model of virally induced deafness" @default.
- W2941279309 doi "https://doi.org/10.1016/j.ajog.2019.10.063" @default.
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