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- W2941431642 abstract "One new flavanonol, demethylmatteucinol ( 1 ), and nine new flavanone glucoside derivatives, matteflavosides H-J ( 2–4 ) and matteuinterates A-F ( 5 – 10 ), were isolated from the rhizomes of Matteuccia intermedia C.Chr., along with 21 known flavanones ( 11 − 31 ). Notably, all of them contain C -methylation in the A-ring. The structures of the compounds were elucidated by spectroscopic methods and chemical derivatization. The α -glycosidase inhibition assay indicated that compounds 12 – 17 showed potent inhibitory activity with IC 50 values of 12.4–69.7 μM, which suggested their hypoglycemic effect. Thirty-one C -methylated flavanones, including ten previously unreported, were isolated from the rhizomes of Matteuccia intermedia . The isolates ( 1 – 9 , 11 – 31 ) were evaluated for their α -glucosidase inhibitory assay, which suggested that compounds 12 – 17 possessed potential hypoglycemic activity (IC 50 12.4–69.7 μM)." @default.
- W2941431642 created "2019-05-03" @default.
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- W2941431642 date "2019-07-01" @default.
- W2941431642 modified "2023-09-23" @default.
- W2941431642 title "C-Methylated flavanones from the rhizomes of Matteuccia intermedia and their α-glucosidase inhibitory activity" @default.
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- W2941431642 doi "https://doi.org/10.1016/j.fitote.2019.04.002" @default.
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