Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941566350> ?p ?o ?g. }
- W2941566350 endingPage "8" @default.
- W2941566350 startingPage "1" @default.
- W2941566350 abstract "Asymmetric block copolymer membranes can be facilely prepared via non-solvent induced phase separation combined with self-assembly. The membrane is characterized by a thin layer of highly ordered and uniform cylindrical nano-channels on top of a non-ordered macroporous sponge-like layer. Up to date, most studies concerning block copolymer membranes are focused on separation applications. In this work, highly adsorptive and adhesive isoporous block copolymer membranes have been fabricated. Because of the functionalization with cyclodextrin, the membrane shows excellent affinity to guest molecules. Moreover, the membrane is biocompatible and is adhesive to various substrates (e.g. glass, silicon, gold and stainless steel). Triclosan as a model drug was utilized to demonstrate the applicability of the membranes as a drug reservoir. A high loading capacity (305.5 μg cm−2) was achieved. The release behavior was investigated under various pH values in vitro. A long-time extended drug release was achieved without showing an initial burst effect. Furthermore, pH-responsive release behavior was observed. The triclosan-loaded membrane exhibited a significant antibacterial effect due to the triclosan release; the diffusion out of the membrane was evaluated using a disc diffusion assay. This study provides great potential for isoporous block copolymer membranes as a delivery platform for a wide variety of biomedical applications." @default.
- W2941566350 created "2019-05-03" @default.
- W2941566350 creator A5010131681 @default.
- W2941566350 creator A5022085329 @default.
- W2941566350 creator A5051160082 @default.
- W2941566350 creator A5055579222 @default.
- W2941566350 creator A5073197434 @default.
- W2941566350 creator A5084429473 @default.
- W2941566350 creator A5090126456 @default.
- W2941566350 date "2019-08-01" @default.
- W2941566350 modified "2023-10-15" @default.
- W2941566350 title "Cyclodextrin-functionalized asymmetric block copolymer films as high-capacity reservoir for drug delivery" @default.
- W2941566350 cites W1524518982 @default.
- W2941566350 cites W1828973643 @default.
- W2941566350 cites W1966599329 @default.
- W2941566350 cites W1968055881 @default.
- W2941566350 cites W1977072597 @default.
- W2941566350 cites W1977084624 @default.
- W2941566350 cites W1984542241 @default.
- W2941566350 cites W1995832168 @default.
- W2941566350 cites W1998506213 @default.
- W2941566350 cites W2010465765 @default.
- W2941566350 cites W2020996314 @default.
- W2941566350 cites W2022242346 @default.
- W2941566350 cites W2027095793 @default.
- W2941566350 cites W2032703598 @default.
- W2941566350 cites W2034406436 @default.
- W2941566350 cites W2049667447 @default.
- W2941566350 cites W2051330852 @default.
- W2941566350 cites W2082741124 @default.
- W2941566350 cites W2083811444 @default.
- W2941566350 cites W2086130473 @default.
- W2941566350 cites W2087581197 @default.
- W2941566350 cites W2088203457 @default.
- W2941566350 cites W2089833935 @default.
- W2941566350 cites W2090156487 @default.
- W2941566350 cites W2091442823 @default.
- W2941566350 cites W2142665028 @default.
- W2941566350 cites W2148797086 @default.
- W2941566350 cites W2149297541 @default.
- W2941566350 cites W2149390196 @default.
- W2941566350 cites W2166934135 @default.
- W2941566350 cites W2301722455 @default.
- W2941566350 cites W2344598639 @default.
- W2941566350 cites W2473796248 @default.
- W2941566350 cites W2585486388 @default.
- W2941566350 cites W2733826998 @default.
- W2941566350 cites W2734458794 @default.
- W2941566350 cites W2739005973 @default.
- W2941566350 cites W2748417965 @default.
- W2941566350 cites W2748886713 @default.
- W2941566350 cites W2753814294 @default.
- W2941566350 cites W2775569991 @default.
- W2941566350 cites W2845010106 @default.
- W2941566350 cites W3098925046 @default.
- W2941566350 cites W4249027976 @default.
- W2941566350 cites W4376596303 @default.
- W2941566350 doi "https://doi.org/10.1016/j.memsci.2019.04.039" @default.
- W2941566350 hasPublicationYear "2019" @default.
- W2941566350 type Work @default.
- W2941566350 sameAs 2941566350 @default.
- W2941566350 citedByCount "10" @default.
- W2941566350 countsByYear W29415663502020 @default.
- W2941566350 countsByYear W29415663502021 @default.
- W2941566350 countsByYear W29415663502022 @default.
- W2941566350 crossrefType "journal-article" @default.
- W2941566350 hasAuthorship W2941566350A5010131681 @default.
- W2941566350 hasAuthorship W2941566350A5022085329 @default.
- W2941566350 hasAuthorship W2941566350A5051160082 @default.
- W2941566350 hasAuthorship W2941566350A5055579222 @default.
- W2941566350 hasAuthorship W2941566350A5073197434 @default.
- W2941566350 hasAuthorship W2941566350A5084429473 @default.
- W2941566350 hasAuthorship W2941566350A5090126456 @default.
- W2941566350 hasConcept C127413603 @default.
- W2941566350 hasConcept C15920480 @default.
- W2941566350 hasConcept C159985019 @default.
- W2941566350 hasConcept C171250308 @default.
- W2941566350 hasConcept C185592680 @default.
- W2941566350 hasConcept C188027245 @default.
- W2941566350 hasConcept C192562407 @default.
- W2941566350 hasConcept C2779227376 @default.
- W2941566350 hasConcept C2779433975 @default.
- W2941566350 hasConcept C2779820397 @default.
- W2941566350 hasConcept C41625074 @default.
- W2941566350 hasConcept C42360764 @default.
- W2941566350 hasConcept C43617362 @default.
- W2941566350 hasConcept C521977710 @default.
- W2941566350 hasConcept C55493867 @default.
- W2941566350 hasConcept C68928338 @default.
- W2941566350 hasConceptScore W2941566350C127413603 @default.
- W2941566350 hasConceptScore W2941566350C15920480 @default.
- W2941566350 hasConceptScore W2941566350C159985019 @default.
- W2941566350 hasConceptScore W2941566350C171250308 @default.
- W2941566350 hasConceptScore W2941566350C185592680 @default.
- W2941566350 hasConceptScore W2941566350C188027245 @default.
- W2941566350 hasConceptScore W2941566350C192562407 @default.
- W2941566350 hasConceptScore W2941566350C2779227376 @default.
- W2941566350 hasConceptScore W2941566350C2779433975 @default.