Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941628138> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2941628138 abstract "Herpes simplex encephalitis (HSE) occurring within 30 days after neurosurgery for solid CNS tumors is underrecognized and underreported but remains important because of high morbidity and mortality. We present the case of a 41-year-old woman who had HSE after craniopharyngioma surgery, and delayed recognition and treatment led to a poor outcome. Subsequently, we review reported HSE cases after neurosurgery for solid CNS tumors and describe outcomes after treatment with and without acyclovir.A literature search was performed for cases meeting the above criteria. Information was gathered regarding patient demographics, tumor types, symptoms, diagnostic workup, therapy, and outcomes.Eighteen cases were studied. Encephalopathy, fever, and seizures were the most common symptoms. A majority of patients (78%) received IV acyclovir, with a 79% survival rate with treatment. Mortality rate was 100% in untreated cases. The median time to starting acyclovir was 17 postoperative days (range, 8-53 days). Most patients received steroids, but its use was not associated with a specific outcome.HSE may develop following neurosurgical resection, and the threshold for suspicion of this condition should be extremely low in a patient who shows compatible symptoms (encephalopathy, fever, or seizures) or does not recover as planned. Moreover, in case of suspicion of HSE, acyclovir should be promptly started until infection can be definitely ruled out. A delay in diagnosis of HSE and failure to treat may result in severe morbidity as well as mortality. This observation may warrant further study." @default.
- W2941628138 created "2019-05-03" @default.
- W2941628138 creator A5016854610 @default.
- W2941628138 creator A5027227826 @default.
- W2941628138 creator A5045792465 @default.
- W2941628138 creator A5065260287 @default.
- W2941628138 creator A5075241867 @default.
- W2941628138 date "2019-04-22" @default.
- W2941628138 modified "2023-09-28" @default.
- W2941628138 title "Outcomes with acyclovir treatment in herpes simplex encephalitis after surgery for solid CNS tumors: a case report and systematic review of the literature" @default.
- W2941628138 cites W1179018776 @default.
- W2941628138 cites W1506043602 @default.
- W2941628138 cites W1970834164 @default.
- W2941628138 cites W1989469055 @default.
- W2941628138 cites W2006587550 @default.
- W2941628138 cites W2039533469 @default.
- W2941628138 cites W2051329411 @default.
- W2941628138 cites W2062454221 @default.
- W2941628138 cites W2064820997 @default.
- W2941628138 cites W2069184713 @default.
- W2941628138 cites W2074851438 @default.
- W2941628138 cites W2082725856 @default.
- W2941628138 cites W2083331221 @default.
- W2941628138 cites W2095757228 @default.
- W2941628138 cites W2109950770 @default.
- W2941628138 cites W2122346420 @default.
- W2941628138 cites W2123621748 @default.
- W2941628138 cites W2141039294 @default.
- W2941628138 cites W2148316439 @default.
- W2941628138 cites W2164676319 @default.
- W2941628138 cites W2264240846 @default.
- W2941628138 cites W2403870716 @default.
- W2941628138 cites W2622698101 @default.
- W2941628138 cites W2885949128 @default.
- W2941628138 cites W2328833403 @default.
- W2941628138 doi "https://doi.org/10.1093/nop/npz007" @default.
- W2941628138 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6660819" @default.
- W2941628138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31386089" @default.
- W2941628138 hasPublicationYear "2019" @default.
- W2941628138 type Work @default.
- W2941628138 sameAs 2941628138 @default.
- W2941628138 citedByCount "1" @default.
- W2941628138 countsByYear W29416281382021 @default.
- W2941628138 crossrefType "journal-article" @default.
- W2941628138 hasAuthorship W2941628138A5016854610 @default.
- W2941628138 hasAuthorship W2941628138A5027227826 @default.
- W2941628138 hasAuthorship W2941628138A5045792465 @default.
- W2941628138 hasAuthorship W2941628138A5065260287 @default.
- W2941628138 hasAuthorship W2941628138A5075241867 @default.
- W2941628138 hasBestOaLocation W29416281382 @default.
- W2941628138 hasConcept C126322002 @default.
- W2941628138 hasConcept C12770488 @default.
- W2941628138 hasConcept C141071460 @default.
- W2941628138 hasConcept C159047783 @default.
- W2941628138 hasConcept C179755657 @default.
- W2941628138 hasConcept C187212893 @default.
- W2941628138 hasConcept C2522874641 @default.
- W2941628138 hasConcept C2778621155 @default.
- W2941628138 hasConcept C71924100 @default.
- W2941628138 hasConcept C83455156 @default.
- W2941628138 hasConceptScore W2941628138C126322002 @default.
- W2941628138 hasConceptScore W2941628138C12770488 @default.
- W2941628138 hasConceptScore W2941628138C141071460 @default.
- W2941628138 hasConceptScore W2941628138C159047783 @default.
- W2941628138 hasConceptScore W2941628138C179755657 @default.
- W2941628138 hasConceptScore W2941628138C187212893 @default.
- W2941628138 hasConceptScore W2941628138C2522874641 @default.
- W2941628138 hasConceptScore W2941628138C2778621155 @default.
- W2941628138 hasConceptScore W2941628138C71924100 @default.
- W2941628138 hasConceptScore W2941628138C83455156 @default.
- W2941628138 hasLocation W29416281381 @default.
- W2941628138 hasLocation W29416281382 @default.
- W2941628138 hasLocation W29416281383 @default.
- W2941628138 hasLocation W29416281384 @default.
- W2941628138 hasOpenAccess W2941628138 @default.
- W2941628138 hasPrimaryLocation W29416281381 @default.
- W2941628138 isParatext "false" @default.
- W2941628138 isRetracted "false" @default.
- W2941628138 magId "2941628138" @default.
- W2941628138 workType "article" @default.