FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941704842> ?p ?o ?g. }

• W2941704842 abstract "You have accessJournal of UrologyKidney Cancer: Advanced (including Drug Therapy) I (PD03)1 Apr 2019PD03-06 IMPACT OF C-REACTIVE PROTEIN-ALBUMIN RATIO (CAR) ON PREDICTION OF PROGNOSIS IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA Sakae Konishi*, Shingo Hatakeyama, Toshiaki Tanaka, Yoshinori Ikehata, Toshikazu Tanaka, Naoki Fujita, Yusuke Ishibashi, Hayato Yamamoto, Takahiro Yoneyama, Yasuhiro Hashimoto, Kazuaki Yoshikawa, Toshiaki Kawaguchi, Naoya Masumori, Hiroshi Kitamura, and Chikara Ohyama Sakae Konishi*Sakae Konishi* More articles by this author , Shingo HatakeyamaShingo Hatakeyama More articles by this author , Toshiaki TanakaToshiaki Tanaka More articles by this author , Yoshinori IkehataYoshinori Ikehata More articles by this author , Toshikazu TanakaToshikazu Tanaka More articles by this author , Naoki FujitaNaoki Fujita More articles by this author , Yusuke IshibashiYusuke Ishibashi More articles by this author , Hayato YamamotoHayato Yamamoto More articles by this author , Takahiro YoneyamaTakahiro Yoneyama More articles by this author , Yasuhiro HashimotoYasuhiro Hashimoto More articles by this author , Kazuaki YoshikawaKazuaki Yoshikawa More articles by this author , Toshiaki KawaguchiToshiaki Kawaguchi More articles by this author , Naoya MasumoriNaoya Masumori More articles by this author , Hiroshi KitamuraHiroshi Kitamura More articles by this author , and Chikara OhyamaChikara Ohyama More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000555042.11071.f2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: To evaluate the impact of pretreatment C-reactive protein/albumin ratio (CAR) on prognosis and the effect of adding CAR in the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) model for prognosis discrimination in patients with metastatic renal cell carcinoma (mRCC). METHODS: A retrospective study was performed in 176 patients with mRCC who received first-line tyrosine kinase inhibitors. Prognostic value of CAR was tested using the Kaplan–Meier method and Cox proportional regression models. The effect of adding CAR in the IMDC model (IMDC-CAR) for overall survival (OS) discrimination was evaluated using receiver operator characteristic (ROC) curves, integrated discrimination improvement (IDI), and net reclassification improvement (NRI). RESULTS: CAR was significantly different among the IMDC favorable-, intermediate-, and poor-risk groups. The optimal cutoff value of CAR for OS was defined as 0.05 by ROC analysis, and patients were stratified into two groups: CAR-low (<0.05) and CAR-high (≥0.05). The CAR-high group was significantly associated with poor OS compared to the CAR-low group. The multivariate analysis confirmed that CAR and the IMDC model were independently associated with OS. The area under the curve (AUC) was significantly different between the IMDC (0.689) and IMDC-CAR (0.720) models for the NRI 0.458 (P = 0.002) and IDI 0.05 (P = 0.007). CONCLUSIONS: CAR is a simple and independent predictor of OS in patients with mRCC. Predictive activity was significantly improved in the IMDC-CAR model compared to the IMDC model. Source of Funding: none Hirosaki, Japan; Sapporo, Japan; Toyama, Japan; Hirosaki, Japan; Mutsu, Japan; Aomori, Japan; Sapporo, Japan; Toyama, Japan; Hirosaki, Japan© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e69-e70 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sakae Konishi* More articles by this author Shingo Hatakeyama More articles by this author Toshiaki Tanaka More articles by this author Yoshinori Ikehata More articles by this author Toshikazu Tanaka More articles by this author Naoki Fujita More articles by this author Yusuke Ishibashi More articles by this author Hayato Yamamoto More articles by this author Takahiro Yoneyama More articles by this author Yasuhiro Hashimoto More articles by this author Kazuaki Yoshikawa More articles by this author Toshiaki Kawaguchi More articles by this author Naoya Masumori More articles by this author Hiroshi Kitamura More articles by this author Chikara Ohyama More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
• W2941704842 created "2019-05-03" @default.
• W2941704842 creator A5000893018 @default.
• W2941704842 creator A5006389625 @default.
• W2941704842 creator A5013782799 @default.
• W2941704842 creator A5016000795 @default.
• W2941704842 creator A5022418773 @default.
• W2941704842 creator A5026803124 @default.
• W2941704842 creator A5029041044 @default.
• W2941704842 creator A5034118045 @default.
• W2941704842 creator A5037711521 @default.
• W2941704842 creator A5051131587 @default.
• W2941704842 creator A5066536967 @default.
• W2941704842 creator A5070129542 @default.
• W2941704842 creator A5076075777 @default.
• W2941704842 creator A5076273759 @default.
• W2941704842 creator A5083918280 @default.
• W2941704842 date "2019-04-01" @default.
• W2941704842 modified "2023-10-16" @default.
• W2941704842 title "PD03-06 IMPACT OF C-REACTIVE PROTEIN-ALBUMIN RATIO (CAR) ON PREDICTION OF PROGNOSIS IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA" @default.
• W2941704842 doi "https://doi.org/10.1097/01.ju.0000555042.11071.f2" @default.
• W2941704842 hasPublicationYear "2019" @default.
• W2941704842 type Work @default.
• W2941704842 sameAs 2941704842 @default.
• W2941704842 citedByCount "0" @default.
• W2941704842 crossrefType "journal-article" @default.
• W2941704842 hasAuthorship W2941704842A5000893018 @default.
• W2941704842 hasAuthorship W2941704842A5006389625 @default.
• W2941704842 hasAuthorship W2941704842A5013782799 @default.
• W2941704842 hasAuthorship W2941704842A5016000795 @default.
• W2941704842 hasAuthorship W2941704842A5022418773 @default.
• W2941704842 hasAuthorship W2941704842A5026803124 @default.
• W2941704842 hasAuthorship W2941704842A5029041044 @default.
• W2941704842 hasAuthorship W2941704842A5034118045 @default.
• W2941704842 hasAuthorship W2941704842A5037711521 @default.
• W2941704842 hasAuthorship W2941704842A5051131587 @default.
• W2941704842 hasAuthorship W2941704842A5066536967 @default.
• W2941704842 hasAuthorship W2941704842A5070129542 @default.
• W2941704842 hasAuthorship W2941704842A5076075777 @default.
• W2941704842 hasAuthorship W2941704842A5076273759 @default.
• W2941704842 hasAuthorship W2941704842A5083918280 @default.
• W2941704842 hasBestOaLocation W29417048421 @default.
• W2941704842 hasConcept C143998085 @default.
• W2941704842 hasConcept C2777472916 @default.
• W2941704842 hasConcept C71924100 @default.
• W2941704842 hasConceptScore W2941704842C143998085 @default.
• W2941704842 hasConceptScore W2941704842C2777472916 @default.
• W2941704842 hasConceptScore W2941704842C71924100 @default.
• W2941704842 hasIssue "Supplement 4" @default.
• W2941704842 hasLocation W29417048421 @default.
• W2941704842 hasOpenAccess W2941704842 @default.
• W2941704842 hasPrimaryLocation W29417048421 @default.
• W2941704842 hasRelatedWork W1994903659 @default.
• W2941704842 hasRelatedWork W1997169225 @default.
• W2941704842 hasRelatedWork W2005149537 @default.
• W2941704842 hasRelatedWork W2045737731 @default.
• W2941704842 hasRelatedWork W2082858124 @default.
• W2941704842 hasRelatedWork W2360810719 @default.
• W2941704842 hasRelatedWork W2362434115 @default.
• W2941704842 hasRelatedWork W2436311630 @default.
• W2941704842 hasRelatedWork W2790557737 @default.
• W2941704842 hasRelatedWork W3039871065 @default.
• W2941704842 hasVolume "201" @default.
• W2941704842 isParatext "false" @default.
• W2941704842 isRetracted "false" @default.
• W2941704842 magId "2941704842" @default.
• W2941704842 workType "article" @default.