FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941750210> ?p ?o ?g. }

• W2941750210 endingPage "302" @default.
• W2941750210 startingPage "294" @default.
• W2941750210 abstract "To identify the significance of autophagy in lupus nephritis (LN).The number of autophagosomes in podocytes was counted and the expression of multiple molecular markers associated with autophagy was evaluated in LN specimens: in renal biopsy specimens from 90 patients with LN and 15 healthy controls, autophagosomes in podocytes were counted using transmission electron microscopy and the expression levels of four autophage related proteins including Beclin-1, microtubule-associated protein light chain 3 (LC3), autophagy-related gene 7 (Atg7), and UNC-51-like kinase 1 (ULK1) were measured using immunohistochemistry.The number of autophagosomes in patients with LN types III, IV, and combined V-IV type were significantly higher than in controls (p < 0.0001; p < 0.0001; p = 0.009, respectively). However, the autophagosomes numbers in patients with II and V types LN were significantly lower than controls (both p < 0.0001). Various levels of marker expression were identified, and they correlated significantly with LN pathology classifications. Moreover, the percentage of marker expression in LN types III, IV and V-IV were significantly higher than controls (p < 0.05), while that in types II and V were lower than controls, although the difference for LC3 and ULK1 was not statistically significant.Autophagy activity and expression pattern of autophagy-related markers in podocytes were significantly positively correlated with LN of types III, IV, and V-IV, but negatively correlated with II and V types. Therefore autophagy could be a useful predictor of LN pathology type, and be informative and helpful in the development of treatment strategies in clinical settings." @default.
• W2941750210 created "2019-05-03" @default.
• W2941750210 creator A5003106997 @default.
• W2941750210 creator A5007168135 @default.
• W2941750210 creator A5013793458 @default.
• W2941750210 creator A5015101913 @default.
• W2941750210 creator A5045917913 @default.
• W2941750210 creator A5058481257 @default.
• W2941750210 date "2019-01-01" @default.
• W2941750210 modified "2023-10-17" @default.
• W2941750210 title "Autophagy activity and expression pattern of autophagy-related markers in the podocytes of patients with lupus nephritis: association with pathological classification" @default.
• W2941750210 cites W119159189 @default.
• W2941750210 cites W1561776895 @default.
• W2941750210 cites W1974146917 @default.
• W2941750210 cites W1979592270 @default.
• W2941750210 cites W1985124617 @default.
• W2941750210 cites W1998399313 @default.
• W2941750210 cites W2001591494 @default.
• W2941750210 cites W2018030039 @default.
• W2941750210 cites W2020260798 @default.
• W2941750210 cites W2020771162 @default.
• W2941750210 cites W2042986504 @default.
• W2941750210 cites W2052388933 @default.
• W2941750210 cites W2054300567 @default.
• W2941750210 cites W2081057817 @default.
• W2941750210 cites W2097593047 @default.
• W2941750210 cites W2101069711 @default.
• W2941750210 cites W2111940985 @default.
• W2941750210 cites W2128852607 @default.
• W2941750210 cites W2130127620 @default.
• W2941750210 cites W2151170909 @default.
• W2941750210 cites W2151276321 @default.
• W2941750210 cites W2160308181 @default.
• W2941750210 cites W2164778558 @default.
• W2941750210 doi "https://doi.org/10.1080/0886022x.2019.1598432" @default.
• W2941750210 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6493218" @default.
• W2941750210 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31014158" @default.
• W2941750210 hasPublicationYear "2019" @default.
• W2941750210 type Work @default.
• W2941750210 sameAs 2941750210 @default.
• W2941750210 citedByCount "10" @default.
• W2941750210 countsByYear W29417502102019 @default.
• W2941750210 countsByYear W29417502102020 @default.
• W2941750210 countsByYear W29417502102021 @default.
• W2941750210 countsByYear W29417502102022 @default.
• W2941750210 countsByYear W29417502102023 @default.
• W2941750210 crossrefType "journal-article" @default.
• W2941750210 hasAuthorship W2941750210A5003106997 @default.
• W2941750210 hasAuthorship W2941750210A5007168135 @default.
• W2941750210 hasAuthorship W2941750210A5013793458 @default.
• W2941750210 hasAuthorship W2941750210A5015101913 @default.
• W2941750210 hasAuthorship W2941750210A5045917913 @default.
• W2941750210 hasAuthorship W2941750210A5058481257 @default.
• W2941750210 hasBestOaLocation W29417502101 @default.
• W2941750210 hasConcept C126322002 @default.
• W2941750210 hasConcept C134018914 @default.
• W2941750210 hasConcept C142724271 @default.
• W2941750210 hasConcept C184235292 @default.
• W2941750210 hasConcept C187092789 @default.
• W2941750210 hasConcept C190283241 @default.
• W2941750210 hasConcept C203522944 @default.
• W2941750210 hasConcept C204232928 @default.
• W2941750210 hasConcept C207886595 @default.
• W2941750210 hasConcept C2775934546 @default.
• W2941750210 hasConcept C2779134260 @default.
• W2941750210 hasConcept C2779912601 @default.
• W2941750210 hasConcept C2780124434 @default.
• W2941750210 hasConcept C55493867 @default.
• W2941750210 hasConcept C71680706 @default.
• W2941750210 hasConcept C71924100 @default.
• W2941750210 hasConcept C86803240 @default.
• W2941750210 hasConcept C95444343 @default.
• W2941750210 hasConcept C97029542 @default.
• W2941750210 hasConceptScore W2941750210C126322002 @default.
• W2941750210 hasConceptScore W2941750210C134018914 @default.
• W2941750210 hasConceptScore W2941750210C142724271 @default.
• W2941750210 hasConceptScore W2941750210C184235292 @default.
• W2941750210 hasConceptScore W2941750210C187092789 @default.
• W2941750210 hasConceptScore W2941750210C190283241 @default.
• W2941750210 hasConceptScore W2941750210C203522944 @default.
• W2941750210 hasConceptScore W2941750210C204232928 @default.
• W2941750210 hasConceptScore W2941750210C207886595 @default.
• W2941750210 hasConceptScore W2941750210C2775934546 @default.
• W2941750210 hasConceptScore W2941750210C2779134260 @default.
• W2941750210 hasConceptScore W2941750210C2779912601 @default.
• W2941750210 hasConceptScore W2941750210C2780124434 @default.
• W2941750210 hasConceptScore W2941750210C55493867 @default.
• W2941750210 hasConceptScore W2941750210C71680706 @default.
• W2941750210 hasConceptScore W2941750210C71924100 @default.
• W2941750210 hasConceptScore W2941750210C86803240 @default.
• W2941750210 hasConceptScore W2941750210C95444343 @default.
• W2941750210 hasConceptScore W2941750210C97029542 @default.
• W2941750210 hasIssue "1" @default.
• W2941750210 hasLocation W29417502101 @default.
• W2941750210 hasLocation W29417502102 @default.
• W2941750210 hasLocation W29417502103 @default.
• W2941750210 hasLocation W29417502104 @default.
• W2941750210 hasOpenAccess W2941750210 @default.

• next