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- W2941944795 abstract "Abstract Autoantibodies (AAbs) against von Willebrand factor (vWF)-cleaving protease ADAMTS13 causally relate to thrombotic thrombocytopenic purpura (TTP). How anti-ADAMTS13 AAbs are generated is unknown. Starting from reports according to which influenza infection can trigger TTP by the production of ADAMTS13 AAbs, this study explores influenza viruses and ADAMTS13 protein for common peptide sequences that might underlie anti-influenza immune responses able to cross-react with ADAMTS13. Results document that numerous peptides are shared between influenza A and B viruses and ADAMTS13, thus supporting the hypothesis of cross-reactivity as a mechanism driving the generation of anti-ADAMTS13 AAbs." @default.
- W2941944795 created "2019-05-03" @default.
- W2941944795 creator A5040099455 @default.
- W2941944795 date "2018-12-30" @default.
- W2941944795 modified "2023-10-14" @default.
- W2941944795 title "From influenza infection to anti-ADAMTS13 autoantibodies via cross-reactivity" @default.
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- W2941944795 doi "https://doi.org/10.2478/ii-2019-0002" @default.
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