FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941983742> ?p ?o ?g. }

• W2941983742 endingPage "1724" @default.
• W2941983742 startingPage "1709" @default.
• W2941983742 abstract "Protein synthesis and degradation are essential processes that regulate cell status. Because labeling in bulky organs, such as fruits, is difficult, we developed a modeling approach to study protein turnover at the global scale in developing tomato (Solanum lycopersicum) fruit. Quantitative data were collected for transcripts and proteins during fruit development. Clustering analysis showed smaller changes in protein abundance compared to mRNA abundance. Furthermore, protein and transcript abundance were poorly correlated, and the coefficient of correlation decreased during fruit development and ripening, with transcript levels decreasing more than protein levels. A mathematical model with one ordinary differential equation was used to estimate translation (kt ) and degradation (kd ) rate constants for almost 2,400 detected transcript-protein pairs and was satisfactorily fitted for >1,000 pairs. The model predicted median values of ∼2 min for the translation of a protein, and a protein lifetime of ∼11 d. The constants were validated and inspected for biological relevance. Proteins involved in protein synthesis had higher kt and kd values, indicating that the protein machinery is particularly flexible. Our model also predicts that protein concentration is more strongly affected by the rate of translation than that of degradation." @default.
• W2941983742 created "2019-05-03" @default.
• W2941983742 creator A5002433681 @default.
• W2941983742 creator A5011858960 @default.
• W2941983742 creator A5012477824 @default.
• W2941983742 creator A5014163758 @default.
• W2941983742 creator A5016677025 @default.
• W2941983742 creator A5022052345 @default.
• W2941983742 creator A5028779511 @default.
• W2941983742 creator A5038331985 @default.
• W2941983742 creator A5042750215 @default.
• W2941983742 creator A5062150145 @default.
• W2941983742 creator A5063047492 @default.
• W2941983742 creator A5064248958 @default.
• W2941983742 creator A5066445561 @default.
• W2941983742 creator A5067462896 @default.
• W2941983742 creator A5071672311 @default.
• W2941983742 creator A5080116719 @default.
• W2941983742 creator A5082614868 @default.
• W2941983742 creator A5091504728 @default.
• W2941983742 date "2019-04-23" @default.
• W2941983742 modified "2023-10-14" @default.
• W2941983742 title "Modeling Protein Destiny in Developing Fruit" @default.
• W2941983742 cites W1827817154 @default.
• W2941983742 cites W1865467126 @default.
• W2941983742 cites W1973268693 @default.
• W2941983742 cites W1976327004 @default.
• W2941983742 cites W1986683846 @default.
• W2941983742 cites W1994640671 @default.
• W2941983742 cites W1995533600 @default.
• W2941983742 cites W2001552323 @default.
• W2941983742 cites W2008856488 @default.
• W2941983742 cites W2011503994 @default.
• W2941983742 cites W2012057388 @default.
• W2941983742 cites W2013085592 @default.
• W2941983742 cites W2015663603 @default.
• W2941983742 cites W2016097940 @default.
• W2941983742 cites W2019050932 @default.
• W2941983742 cites W2022264229 @default.
• W2941983742 cites W2044104647 @default.
• W2941983742 cites W2050343257 @default.
• W2941983742 cites W2053632669 @default.
• W2941983742 cites W2061659241 @default.
• W2941983742 cites W2064572325 @default.
• W2941983742 cites W2077167869 @default.
• W2941983742 cites W2082035661 @default.
• W2941983742 cites W2091312350 @default.
• W2941983742 cites W2092594118 @default.
• W2941983742 cites W2097360283 @default.
• W2941983742 cites W2113934702 @default.
• W2941983742 cites W2114850508 @default.
• W2941983742 cites W2118258530 @default.
• W2941983742 cites W2118348421 @default.
• W2941983742 cites W2128551987 @default.
• W2941983742 cites W2128558671 @default.
• W2941983742 cites W2131036432 @default.
• W2941983742 cites W2131271579 @default.
• W2941983742 cites W2134526812 @default.
• W2941983742 cites W2136868446 @default.
• W2941983742 cites W2139595602 @default.
• W2941983742 cites W2150566147 @default.
• W2941983742 cites W2152504785 @default.
• W2941983742 cites W2152983548 @default.
• W2941983742 cites W2157848631 @default.
• W2941983742 cites W2165047972 @default.
• W2941983742 cites W2166752189 @default.
• W2941983742 cites W2169456326 @default.
• W2941983742 cites W2171464043 @default.
• W2941983742 cites W2266860624 @default.
• W2941983742 cites W2330238097 @default.
• W2941983742 cites W2334501944 @default.
• W2941983742 cites W2466451242 @default.
• W2941983742 cites W2490412292 @default.
• W2941983742 cites W2553259743 @default.
• W2941983742 cites W2560523813 @default.
• W2941983742 cites W2582331638 @default.
• W2941983742 cites W2583066447 @default.
• W2941983742 cites W2597816781 @default.
• W2941983742 cites W2606048459 @default.
• W2941983742 cites W2619962439 @default.
• W2941983742 cites W2778035878 @default.
• W2941983742 cites W2783734426 @default.
• W2941983742 cites W2791507623 @default.
• W2941983742 cites W2800506093 @default.
• W2941983742 cites W2811299147 @default.
• W2941983742 cites W2897486762 @default.
• W2941983742 cites W2899760200 @default.
• W2941983742 cites W2909224061 @default.
• W2941983742 doi "https://doi.org/10.1104/pp.19.00086" @default.
• W2941983742 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6752906" @default.
• W2941983742 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31015299" @default.
• W2941983742 hasPublicationYear "2019" @default.
• W2941983742 type Work @default.
• W2941983742 sameAs 2941983742 @default.
• W2941983742 citedByCount "19" @default.
• W2941983742 countsByYear W29419837422019 @default.
• W2941983742 countsByYear W29419837422020 @default.
• W2941983742 countsByYear W29419837422021 @default.

• next