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- W2942396721 abstract "Hypercholesterolemie je vĂ˝znamnĂ˝ rizikovĂ˝ faktor pro aterosklerotickĂŠ vaskulĂĄrnĂ nemoci. Epidemiologie sleduje vĂ˝skyt (prevalenci), incidenci a moĹžnosti ovlivnÄnĂ (intervence) rizikovĂŠho faktoru nebo nemoci. V ÄlĂĄnku podĂĄvĂĄme pĹehled observaÄnĂch epidemiologickĂ˝ch studiĂ, intervenÄnĂch studiĂ, dostupnĂŠ farmakoterapie a perspektiv lĂŠÄby hypercholesterolemie. PrvnĂ epidemiologickĂŠ studie, jako je Framingham Heart Study nebo MRFIT, pĹinesly dĹŻkazy o asociaci hyperlipidemie a incidence kardiovaskulĂĄrnĂch (KV) onemocnÄnĂ. DalĹĄĂ studie, jako napĹ. North Karēlia Project, prokĂĄzaly, Ĺže intervence rizikovĂ˝ch faktorĹŻ KV onemocnÄnĂ na Ăşrovni celĂŠ populace mĂĄ smysl. IntervenÄnĂ studie zejmĂŠna se statiny potvrdily ĂşÄelnost sniĹžovĂĄnĂ hladin LDL-cholesterolu k nĂzkĂ˝m hodnotĂĄm s cĂlem snĂĹženĂ KV morbidity a KV i celkovĂŠ mortality. Kontrola rizikovĂ˝ch faktorĹŻ KV onemocnÄnĂ zĹŻstĂĄvĂĄ nedostateÄnĂĄ." @default.
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- W2942396721 date "2018-01-01" @default.
- W2942396721 modified "2023-10-16" @default.
- W2942396721 title "Epidemiology of hypercholesterolemia" @default.
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- W2942396721 doi "https://doi.org/10.36290/vnl.2018.005" @default.
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