FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2942536675> ?p ?o ?g. }

• W2942536675 abstract "The aim of this study was to clarify the association between expression of human leukocyte antigen (HLA) class I in non‑small‑cell lung cancer (NSCLC) cells and patient survival. To address this, immunohistochemical staining for HLA class I was performed on specimens from 111 patients with NSCLC, and overall survival curves were compared using the log‑rank test. In addition, multivariate analyses were performed using Cox's proportional hazard model. The cases were divided into 5 classes based on the expression of HLA class I heavy chain and β2‑microglobulin. The overall survival rate for patients with tumors lacking HLA class I heavy chain (30 cases; 27.0%) was significantly decreased. The multivariate analysis demonstrated that the absence of HLA class I heavy chain was an independent predictor of poor prognosis. There was a trend towards an unfavorable prognosis for patients whose tumors did not express β2‑microglobulin (57 cases; 51.4%). Downregulation of HLA class I heavy chain expression was significantly associated with the downregulation of β2‑microglobulin. Cases lacking HLA class I heavy chain as well as β2‑microglobulin expression (23 cases; 20.7%) had a statistically significant unfavorable prognosis compared with other cases. The present findings demonstrate that the lack of HLA class I heavy chain expression in tumor cells is an independent prognostic factor for poor NSCLC survival, and is likely to exert an important influence on immune surveillance in patients." @default.
• W2942536675 created "2019-05-09" @default.
• W2942536675 creator A5001950970 @default.
• W2942536675 creator A5003853385 @default.
• W2942536675 creator A5006364648 @default.
• W2942536675 creator A5025499235 @default.
• W2942536675 creator A5050984306 @default.
• W2942536675 creator A5052504412 @default.
• W2942536675 creator A5054290437 @default.
• W2942536675 creator A5063122275 @default.
• W2942536675 creator A5090915905 @default.
• W2942536675 date "2019-04-30" @default.
• W2942536675 modified "2023-09-27" @default.
• W2942536675 title "Downregulated expression of human leukocyte antigen class I heavy chain is associated with poor prognosis in non‑small‑cell lung cancer" @default.
• W2942536675 cites W1572974196 @default.
• W2942536675 cites W1642873092 @default.
• W2942536675 cites W1965882390 @default.
• W2942536675 cites W1979538859 @default.
• W2942536675 cites W1981445628 @default.
• W2942536675 cites W1983671868 @default.
• W2942536675 cites W1992752083 @default.
• W2942536675 cites W1993312546 @default.
• W2942536675 cites W2023291165 @default.
• W2942536675 cites W2028433016 @default.
• W2942536675 cites W2035589771 @default.
• W2942536675 cites W2038032899 @default.
• W2942536675 cites W2040925643 @default.
• W2942536675 cites W2046972425 @default.
• W2942536675 cites W2054844932 @default.
• W2942536675 cites W2066373441 @default.
• W2942536675 cites W2073520179 @default.
• W2942536675 cites W2083208194 @default.
• W2942536675 cites W2107453087 @default.
• W2942536675 cites W2116140198 @default.
• W2942536675 cites W2121626779 @default.
• W2942536675 cites W2124430059 @default.
• W2942536675 cites W2136731993 @default.
• W2942536675 cites W2143458560 @default.
• W2942536675 cites W2155629434 @default.
• W2942536675 cites W2161380040 @default.
• W2942536675 cites W2167551318 @default.
• W2942536675 cites W2251438188 @default.
• W2942536675 cites W2469157024 @default.
• W2942536675 cites W2560367415 @default.
• W2942536675 doi "https://doi.org/10.3892/ol.2019.10293" @default.
• W2942536675 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6540002" @default.
• W2942536675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31289480" @default.
• W2942536675 hasPublicationYear "2019" @default.
• W2942536675 type Work @default.
• W2942536675 sameAs 2942536675 @default.
• W2942536675 citedByCount "11" @default.
• W2942536675 countsByYear W29425366752020 @default.
• W2942536675 countsByYear W29425366752021 @default.
• W2942536675 countsByYear W29425366752022 @default.
• W2942536675 countsByYear W29425366752023 @default.
• W2942536675 crossrefType "journal-article" @default.
• W2942536675 hasAuthorship W2942536675A5001950970 @default.
• W2942536675 hasAuthorship W2942536675A5003853385 @default.
• W2942536675 hasAuthorship W2942536675A5006364648 @default.
• W2942536675 hasAuthorship W2942536675A5025499235 @default.
• W2942536675 hasAuthorship W2942536675A5050984306 @default.
• W2942536675 hasAuthorship W2942536675A5052504412 @default.
• W2942536675 hasAuthorship W2942536675A5054290437 @default.
• W2942536675 hasAuthorship W2942536675A5063122275 @default.
• W2942536675 hasAuthorship W2942536675A5090915905 @default.
• W2942536675 hasBestOaLocation W29425366751 @default.
• W2942536675 hasConcept C10515644 @default.
• W2942536675 hasConcept C121608353 @default.
• W2942536675 hasConcept C126322002 @default.
• W2942536675 hasConcept C143998085 @default.
• W2942536675 hasConcept C147483822 @default.
• W2942536675 hasConcept C188280979 @default.
• W2942536675 hasConcept C203014093 @default.
• W2942536675 hasConcept C207103383 @default.
• W2942536675 hasConcept C21957315 @default.
• W2942536675 hasConcept C2776256026 @default.
• W2942536675 hasConcept C2781018059 @default.
• W2942536675 hasConcept C29537977 @default.
• W2942536675 hasConcept C44249647 @default.
• W2942536675 hasConcept C50382708 @default.
• W2942536675 hasConcept C67082663 @default.
• W2942536675 hasConcept C71924100 @default.
• W2942536675 hasConceptScore W2942536675C10515644 @default.
• W2942536675 hasConceptScore W2942536675C121608353 @default.
• W2942536675 hasConceptScore W2942536675C126322002 @default.
• W2942536675 hasConceptScore W2942536675C143998085 @default.
• W2942536675 hasConceptScore W2942536675C147483822 @default.
• W2942536675 hasConceptScore W2942536675C188280979 @default.
• W2942536675 hasConceptScore W2942536675C203014093 @default.
• W2942536675 hasConceptScore W2942536675C207103383 @default.
• W2942536675 hasConceptScore W2942536675C21957315 @default.
• W2942536675 hasConceptScore W2942536675C2776256026 @default.
• W2942536675 hasConceptScore W2942536675C2781018059 @default.
• W2942536675 hasConceptScore W2942536675C29537977 @default.
• W2942536675 hasConceptScore W2942536675C44249647 @default.
• W2942536675 hasConceptScore W2942536675C50382708 @default.
• W2942536675 hasConceptScore W2942536675C67082663 @default.
• W2942536675 hasConceptScore W2942536675C71924100 @default.
• W2942536675 hasLocation W29425366751 @default.
• W2942536675 hasLocation W29425366752 @default.

• next