FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2942609098> ?p ?o ?g. }

• W2942609098 endingPage "1234.e4" @default.
• W2942609098 startingPage "1223" @default.
• W2942609098 abstract "Inhibitory interneurons expressing vasoactive intestinal polypeptide (VIP) are known to disinhibit cortical neurons. However, it is unclear how disinhibition, occurring at the single-cell level, interacts with network-level patterns of activity to shape complex behaviors. To address this, we examined the role of prefrontal VIP interneurons in a widely studied mouse behavior: deciding whether to explore or avoid the open arms of an elevated plus maze. VIP interneuron activity increases in the open arms and disinhibits prefrontal responses to hippocampal inputs, which are known to transmit signals related to open arm avoidance. Indeed, inhibiting VIP interneurons disrupts network-level representations of the open arms and decreases open arm avoidance specifically when hippocampal-prefrontal theta synchrony is strong. Thus, VIP interneurons effectively gate the ability of hippocampal input to generate prefrontal representations, which drive avoidance behavior. This shows how VIP interneurons enable cortical circuits to integrate specific inputs into network-level representations that guide complex behaviors. VIDEO ABSTRACT." @default.
• W2942609098 created "2019-05-09" @default.
• W2942609098 creator A5003243629 @default.
• W2942609098 creator A5009087624 @default.
• W2942609098 creator A5015705879 @default.
• W2942609098 creator A5019645416 @default.
• W2942609098 creator A5039232605 @default.
• W2942609098 creator A5043212839 @default.
• W2942609098 creator A5053400747 @default.
• W2942609098 creator A5058890359 @default.
• W2942609098 date "2019-06-01" @default.
• W2942609098 modified "2023-10-15" @default.
• W2942609098 title "VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks" @default.
• W2942609098 cites W1977514547 @default.
• W2942609098 cites W1983784678 @default.
• W2942609098 cites W1991444801 @default.
• W2942609098 cites W1992910467 @default.
• W2942609098 cites W2023595618 @default.
• W2942609098 cites W2042662796 @default.
• W2942609098 cites W2047347093 @default.
• W2942609098 cites W2055766556 @default.
• W2942609098 cites W2057029832 @default.
• W2942609098 cites W2059836587 @default.
• W2942609098 cites W2071358231 @default.
• W2942609098 cites W2084145610 @default.
• W2942609098 cites W2089823661 @default.
• W2942609098 cites W2090737759 @default.
• W2942609098 cites W2097237250 @default.
• W2942609098 cites W2101052714 @default.
• W2942609098 cites W2108888119 @default.
• W2942609098 cites W2171332611 @default.
• W2942609098 cites W2254443919 @default.
• W2942609098 cites W2275621485 @default.
• W2942609098 cites W2306521117 @default.
• W2942609098 cites W2514039802 @default.
• W2942609098 cites W2524300278 @default.
• W2942609098 cites W2553564376 @default.
• W2942609098 cites W2563958496 @default.
• W2942609098 cites W2566853258 @default.
• W2942609098 cites W2580178003 @default.
• W2942609098 cites W2607724497 @default.
• W2942609098 cites W2804636914 @default.
• W2942609098 doi "https://doi.org/10.1016/j.neuron.2019.04.001" @default.
• W2942609098 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6800223" @default.
• W2942609098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31053407" @default.
• W2942609098 hasPublicationYear "2019" @default.
• W2942609098 type Work @default.
• W2942609098 sameAs 2942609098 @default.
• W2942609098 citedByCount "61" @default.
• W2942609098 countsByYear W29426090982019 @default.
• W2942609098 countsByYear W29426090982020 @default.
• W2942609098 countsByYear W29426090982021 @default.
• W2942609098 countsByYear W29426090982022 @default.
• W2942609098 countsByYear W29426090982023 @default.
• W2942609098 crossrefType "journal-article" @default.
• W2942609098 hasAuthorship W2942609098A5003243629 @default.
• W2942609098 hasAuthorship W2942609098A5009087624 @default.
• W2942609098 hasAuthorship W2942609098A5015705879 @default.
• W2942609098 hasAuthorship W2942609098A5019645416 @default.
• W2942609098 hasAuthorship W2942609098A5039232605 @default.
• W2942609098 hasAuthorship W2942609098A5043212839 @default.
• W2942609098 hasAuthorship W2942609098A5053400747 @default.
• W2942609098 hasAuthorship W2942609098A5058890359 @default.
• W2942609098 hasBestOaLocation W29426090981 @default.
• W2942609098 hasConcept C118303440 @default.
• W2942609098 hasConcept C148762608 @default.
• W2942609098 hasConcept C15744967 @default.
• W2942609098 hasConcept C169760540 @default.
• W2942609098 hasConcept C169900460 @default.
• W2942609098 hasConcept C170493617 @default.
• W2942609098 hasConcept C17077164 @default.
• W2942609098 hasConcept C2776599063 @default.
• W2942609098 hasConcept C2779296341 @default.
• W2942609098 hasConcept C2781161787 @default.
• W2942609098 hasConcept C2781195155 @default.
• W2942609098 hasConcept C55493867 @default.
• W2942609098 hasConcept C8330315 @default.
• W2942609098 hasConcept C86803240 @default.
• W2942609098 hasConceptScore W2942609098C118303440 @default.
• W2942609098 hasConceptScore W2942609098C148762608 @default.
• W2942609098 hasConceptScore W2942609098C15744967 @default.
• W2942609098 hasConceptScore W2942609098C169760540 @default.
• W2942609098 hasConceptScore W2942609098C169900460 @default.
• W2942609098 hasConceptScore W2942609098C170493617 @default.
• W2942609098 hasConceptScore W2942609098C17077164 @default.
• W2942609098 hasConceptScore W2942609098C2776599063 @default.
• W2942609098 hasConceptScore W2942609098C2779296341 @default.
• W2942609098 hasConceptScore W2942609098C2781161787 @default.
• W2942609098 hasConceptScore W2942609098C2781195155 @default.
• W2942609098 hasConceptScore W2942609098C55493867 @default.
• W2942609098 hasConceptScore W2942609098C8330315 @default.
• W2942609098 hasConceptScore W2942609098C86803240 @default.
• W2942609098 hasFunder F4320306164 @default.
• W2942609098 hasFunder F4320332161 @default.
• W2942609098 hasFunder F4320337346 @default.
• W2942609098 hasFunder F4320337354 @default.
• W2942609098 hasIssue "6" @default.
• W2942609098 hasLocation W29426090981 @default.

• next