FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2942776977> ?p ?o ?g. }

• W2942776977 endingPage "805" @default.
• W2942776977 startingPage "805" @default.
• W2942776977 abstract "<h3>Importance</h3> Given high rates of opioid-related fatal overdoses, improving naloxone access has become a priority. States have implemented different types of naloxone access laws (NALs) and there is controversy over which of these policies, if any, can curb overdose deaths. We hypothesize that NALs granting direct authority to pharmacists to provide naloxone will have the greatest potential for reducing fatal overdoses. <h3>Objectives</h3> To identify which types of NALs, if any, are associated with reductions in fatal overdoses involving opioids and examine possible implications for nonfatal overdoses. <h3>Design, Setting, and Participants</h3> State-level changes in both fatal and nonfatal overdoses from 2005 to 2016 were examined across the 50 states and the District of Columbia after adoption of NALs using a difference-in-differences approach while estimating the magnitude of the association for each year relative to time of adoption. Policy environments across full state populations were represented in the primary data set. The association for 3 types of NALs was associated: NALs providing direct authority to pharmacists to prescribe, NALs providing indirect authority to prescribe, and other NALs. The study was conducted from January 2017 to January 2019. <h3>Exposures</h3> Fatal and nonfatal overdoses in states that adopted NAL laws were compared with those in states that did not adopt NAL laws. Further consideration was given to the type of NAL passed in terms of its association with these outcomes. We hypothesize that NALs granting direct authority to pharmacists to provide naloxone will have the greatest potential for reducing fatal overdoses. <h3>Main Outcomes and Measures</h3> Fatal overdoses involving opioids were the primary outcome. Secondary outcomes were nonfatal overdoses resulting in emergency department visits and Medicaid naloxone prescriptions. <h3>Results</h3> In this evaluation of the dispensing of naloxone across the United States, NALs granting direct authority to pharmacists were associated with significant reductions in fatal overdoses, but they may also increase nonfatal overdoses seen in emergency department visits. The effect sizes for fatal overdoses grew over time relative to adoption of the NALs. These policies were estimated to reduce opioid-rated fatal overdoses by 0.387 (95% CI, 0.119-0.656;<i>P</i> = .007) per 100 000 people in 3 or more years after adoption. There was little evidence of an association for indirect authority to dispense (increase by 0.121; 95% CI, −0.014 to 0.257;<i>P</i> = .09) and other NALs (increase by 0.094; 95% CI, −0.040 to 0.227;<i>P</i> = .17). <h3>Conclusions and Relevance</h3> Although many states have passed some type of law affecting naloxone availability, only laws allowing direct dispensing by pharmacists appear to be useful. Communities in which access to naloxone is improved should prepare for increases in nonfatal overdoses and link these individuals to effective treatment." @default.
• W2942776977 created "2019-05-09" @default.
• W2942776977 creator A5002919229 @default.
• W2942776977 creator A5056291685 @default.
• W2942776977 creator A5058770372 @default.
• W2942776977 date "2019-06-01" @default.
• W2942776977 modified "2023-10-10" @default.
• W2942776977 title "Association Between State Laws Facilitating Pharmacy Distribution of Naloxone and Risk of Fatal Overdose" @default.
• W2942776977 cites W1490170040 @default.
• W2942776977 cites W1791256761 @default.
• W2942776977 cites W1873301473 @default.
• W2942776977 cites W1968086599 @default.
• W2942776977 cites W2012646589 @default.
• W2942776977 cites W2107097188 @default.
• W2942776977 cites W2123439904 @default.
• W2942776977 cites W2136695126 @default.
• W2942776977 cites W2234849280 @default.
• W2942776977 cites W2269979437 @default.
• W2942776977 cites W2560212357 @default.
• W2942776977 cites W2565481099 @default.
• W2942776977 cites W2570714402 @default.
• W2942776977 cites W2571444892 @default.
• W2942776977 cites W2593775298 @default.
• W2942776977 cites W2595088849 @default.
• W2942776977 cites W2741912761 @default.
• W2942776977 cites W2745114458 @default.
• W2942776977 cites W2792522767 @default.
• W2942776977 cites W2795788666 @default.
• W2942776977 cites W2795838588 @default.
• W2942776977 cites W4200337926 @default.
• W2942776977 doi "https://doi.org/10.1001/jamainternmed.2019.0272" @default.
• W2942776977 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6503576" @default.
• W2942776977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31058922" @default.
• W2942776977 hasPublicationYear "2019" @default.
• W2942776977 type Work @default.
• W2942776977 sameAs 2942776977 @default.
• W2942776977 citedByCount "149" @default.
• W2942776977 countsByYear W29427769772019 @default.
• W2942776977 countsByYear W29427769772020 @default.
• W2942776977 countsByYear W29427769772021 @default.
• W2942776977 countsByYear W29427769772022 @default.
• W2942776977 countsByYear W29427769772023 @default.
• W2942776977 crossrefType "journal-article" @default.
• W2942776977 hasAuthorship W2942776977A5002919229 @default.
• W2942776977 hasAuthorship W2942776977A5056291685 @default.
• W2942776977 hasAuthorship W2942776977A5058770372 @default.
• W2942776977 hasBestOaLocation W29427769771 @default.
• W2942776977 hasConcept C104863432 @default.
• W2942776977 hasConcept C11413529 @default.
• W2942776977 hasConcept C126322002 @default.
• W2942776977 hasConcept C170493617 @default.
• W2942776977 hasConcept C17744445 @default.
• W2942776977 hasConcept C199539241 @default.
• W2942776977 hasConcept C2778750930 @default.
• W2942776977 hasConcept C2779148768 @default.
• W2942776977 hasConcept C2781063702 @default.
• W2942776977 hasConcept C2991908516 @default.
• W2942776977 hasConcept C3116431 @default.
• W2942776977 hasConcept C41008148 @default.
• W2942776977 hasConcept C48103436 @default.
• W2942776977 hasConcept C512399662 @default.
• W2942776977 hasConcept C545542383 @default.
• W2942776977 hasConcept C71924100 @default.
• W2942776977 hasConcept C99454951 @default.
• W2942776977 hasConceptScore W2942776977C104863432 @default.
• W2942776977 hasConceptScore W2942776977C11413529 @default.
• W2942776977 hasConceptScore W2942776977C126322002 @default.
• W2942776977 hasConceptScore W2942776977C170493617 @default.
• W2942776977 hasConceptScore W2942776977C17744445 @default.
• W2942776977 hasConceptScore W2942776977C199539241 @default.
• W2942776977 hasConceptScore W2942776977C2778750930 @default.
• W2942776977 hasConceptScore W2942776977C2779148768 @default.
• W2942776977 hasConceptScore W2942776977C2781063702 @default.
• W2942776977 hasConceptScore W2942776977C2991908516 @default.
• W2942776977 hasConceptScore W2942776977C3116431 @default.
• W2942776977 hasConceptScore W2942776977C41008148 @default.
• W2942776977 hasConceptScore W2942776977C48103436 @default.
• W2942776977 hasConceptScore W2942776977C512399662 @default.
• W2942776977 hasConceptScore W2942776977C545542383 @default.
• W2942776977 hasConceptScore W2942776977C71924100 @default.
• W2942776977 hasConceptScore W2942776977C99454951 @default.
• W2942776977 hasIssue "6" @default.
• W2942776977 hasLocation W29427769771 @default.
• W2942776977 hasLocation W29427769772 @default.
• W2942776977 hasLocation W29427769773 @default.
• W2942776977 hasLocation W29427769774 @default.
• W2942776977 hasOpenAccess W2942776977 @default.
• W2942776977 hasPrimaryLocation W29427769771 @default.
• W2942776977 hasRelatedWork W2058243931 @default.
• W2942776977 hasRelatedWork W2064618509 @default.
• W2942776977 hasRelatedWork W2133446656 @default.
• W2942776977 hasRelatedWork W2574749882 @default.
• W2942776977 hasRelatedWork W2911642310 @default.
• W2942776977 hasRelatedWork W2974005807 @default.
• W2942776977 hasRelatedWork W2989306462 @default.
• W2942776977 hasRelatedWork W3017269474 @default.
• W2942776977 hasRelatedWork W3184393304 @default.
• W2942776977 hasRelatedWork W4205686987 @default.

• next