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- W2942810472 startingPage "222" @default.
- W2942810472 abstract "Primary spinal tumors are rare lesions that require careful clinical management due to their intimate relationship with critical neurovascular structures and the significant associated risk of morbidity. While the advent of molecular and genomic profiling is beginning to impact the management of the cranial counterparts, translation for spinal tumors has lagged behind. Maximal safe surgical resection remains the mainstay of patients with primary spinal tumors, with extent of resection and histology the only consistently identified independent predictors of survival. Adjuvant therapy has had limited impact. To develop targeted neoadjuvant and adjuvant therapies, improve prognostication, and enhance patient selection in spinal oncology, a thorough understanding of the current molecular and genomic landscape of spinal tumors is required. In this review, we detail the epidemiology, current standard-of-care, and molecular features of the most commonly encountered intramedullary spinal cord tumors (IMSCT), intradural extramedullary (IDEM) tumors, and primary spinal column malignancies (PSCM). We further discuss current efforts and future opportunities for integrating molecular advances in spinal oncology with clinical management." @default.
- W2942810472 created "2019-05-09" @default.
- W2942810472 creator A5033202151 @default.
- W2942810472 creator A5063689978 @default.
- W2942810472 creator A5069558252 @default.
- W2942810472 date "2019-05-01" @default.
- W2942810472 modified "2023-10-11" @default.
- W2942810472 title "Molecular foundations of primary spinal tumors—implications for surgical management" @default.
- W2942810472 cites W1500204382 @default.
- W2942810472 cites W1523839218 @default.
- W2942810472 cites W1562702076 @default.
- W2942810472 cites W1563804318 @default.
- W2942810472 cites W1568946701 @default.
- W2942810472 cites W1662857558 @default.
- W2942810472 cites W1749022239 @default.
- W2942810472 cites W1779832721 @default.
- W2942810472 cites W1812256879 @default.
- W2942810472 cites W1873793345 @default.
- W2942810472 cites W1893588436 @default.
- W2942810472 cites W1949037014 @default.
- W2942810472 cites W1967070014 @default.
- W2942810472 cites W1969749217 @default.
- W2942810472 cites W1970605593 @default.
- W2942810472 cites W1972609538 @default.
- W2942810472 cites W1976979641 @default.
- W2942810472 cites W1977306288 @default.
- W2942810472 cites W1978396373 @default.
- W2942810472 cites W1983033726 @default.
- W2942810472 cites W1983509688 @default.
- W2942810472 cites W1983598949 @default.
- W2942810472 cites W1984781494 @default.
- W2942810472 cites W1987311809 @default.
- W2942810472 cites W1988995169 @default.
- W2942810472 cites W1994526222 @default.
- W2942810472 cites W1994786401 @default.
- W2942810472 cites W1995614906 @default.
- W2942810472 cites W1997283418 @default.
- W2942810472 cites W2000381516 @default.
- W2942810472 cites W2000672550 @default.
- W2942810472 cites W2001714217 @default.
- W2942810472 cites W2004481321 @default.
- W2942810472 cites W2011645550 @default.
- W2942810472 cites W2011899910 @default.
- W2942810472 cites W2014347393 @default.
- W2942810472 cites W2015674660 @default.
- W2942810472 cites W2020053538 @default.
- W2942810472 cites W2021657948 @default.
- W2942810472 cites W2024614038 @default.
- W2942810472 cites W2025183726 @default.
- W2942810472 cites W2026467691 @default.
- W2942810472 cites W2028030195 @default.
- W2942810472 cites W2028785929 @default.
- W2942810472 cites W2029578016 @default.
- W2942810472 cites W2029814842 @default.
- W2942810472 cites W2035346960 @default.
- W2942810472 cites W2036019225 @default.
- W2942810472 cites W2037024890 @default.
- W2942810472 cites W2040827479 @default.
- W2942810472 cites W2043021179 @default.
- W2942810472 cites W2044271276 @default.
- W2942810472 cites W2045744952 @default.
- W2942810472 cites W2048513804 @default.
- W2942810472 cites W2051921450 @default.
- W2942810472 cites W2058999338 @default.
- W2942810472 cites W2059047071 @default.
- W2942810472 cites W2062062519 @default.
- W2942810472 cites W2063166500 @default.
- W2942810472 cites W2063360105 @default.
- W2942810472 cites W2065105749 @default.
- W2942810472 cites W2065155886 @default.
- W2942810472 cites W2068284127 @default.
- W2942810472 cites W2068555261 @default.
- W2942810472 cites W2068609875 @default.
- W2942810472 cites W2069552672 @default.
- W2942810472 cites W2073230366 @default.
- W2942810472 cites W2076617775 @default.
- W2942810472 cites W2089489280 @default.
- W2942810472 cites W2093368043 @default.
- W2942810472 cites W2100502400 @default.
- W2942810472 cites W2102418043 @default.
- W2942810472 cites W2112866395 @default.
- W2942810472 cites W2116737402 @default.
- W2942810472 cites W2120155459 @default.
- W2942810472 cites W2124779439 @default.
- W2942810472 cites W2126595521 @default.
- W2942810472 cites W2128140173 @default.
- W2942810472 cites W2129554457 @default.
- W2942810472 cites W2130289633 @default.
- W2942810472 cites W2130882540 @default.
- W2942810472 cites W2131855857 @default.
- W2942810472 cites W2135035484 @default.
- W2942810472 cites W2136279041 @default.
- W2942810472 cites W2141403353 @default.
- W2942810472 cites W2143365343 @default.
- W2942810472 cites W2143619463 @default.
- W2942810472 cites W2144717536 @default.
- W2942810472 cites W2148977460 @default.
- W2942810472 cites W2154170543 @default.