Matches in SemOpenAlex for { <https://semopenalex.org/work/W2943001835> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2943001835 abstract "The hydrophobic nature of phospholipids membrane bilayer represent a selectively permeable barrier of living cells. In recent year, the use of cell-penetrating peptides (CPPs) in the delivery of various cargoes across cellular membranes has been widely explored. Among these, peptide gH625 was identified as a membrane-perturbing domain in the glycoprotein gH of Herpes simplex virus type I. gH625 is able to interacts with biological membranes, traverse them and carry a cargo into the cytoplasm. In this context, the aim of this work is to investigate the ability of the gH625 peptide in the construction of novel materials for therapeutic applications. Therefore, we firstly focused on the combined effects of gH625 peptide and reverse transfection in order to develop a gene delivery platform based on functionalized polyethylenimine (PEI)/DNA polyplexes. Then we analyzed the role of Pt NPs size in influencing the ability of gH625 to escape the endo-lysosomal pathway and deliver particles in the cytosol. Finally, we analyzed the behavior of gH625 in dual-functionalized polymeric carrier systems for targeted drug delivery across the blood-brain barrier." @default.
- W2943001835 created "2019-05-09" @default.
- W2943001835 creator A5065219545 @default.
- W2943001835 date "2017-12-08" @default.
- W2943001835 modified "2023-09-27" @default.
- W2943001835 title "Application of gH625 cell-penetrating peptide in advanced engineered materials" @default.
- W2943001835 hasPublicationYear "2017" @default.
- W2943001835 type Work @default.
- W2943001835 sameAs 2943001835 @default.
- W2943001835 citedByCount "0" @default.
- W2943001835 crossrefType "journal-article" @default.
- W2943001835 hasAuthorship W2943001835A5065219545 @default.
- W2943001835 hasConcept C104317684 @default.
- W2943001835 hasConcept C12554922 @default.
- W2943001835 hasConcept C135983454 @default.
- W2943001835 hasConcept C151730666 @default.
- W2943001835 hasConcept C171250308 @default.
- W2943001835 hasConcept C178790620 @default.
- W2943001835 hasConcept C181199279 @default.
- W2943001835 hasConcept C185592680 @default.
- W2943001835 hasConcept C190062978 @default.
- W2943001835 hasConcept C192562407 @default.
- W2943001835 hasConcept C2775925850 @default.
- W2943001835 hasConcept C2776929087 @default.
- W2943001835 hasConcept C2779281246 @default.
- W2943001835 hasConcept C2779343474 @default.
- W2943001835 hasConcept C2779820397 @default.
- W2943001835 hasConcept C39944091 @default.
- W2943001835 hasConcept C41625074 @default.
- W2943001835 hasConcept C54009773 @default.
- W2943001835 hasConcept C55493867 @default.
- W2943001835 hasConcept C86803240 @default.
- W2943001835 hasConcept C95444343 @default.
- W2943001835 hasConcept C98539663 @default.
- W2943001835 hasConceptScore W2943001835C104317684 @default.
- W2943001835 hasConceptScore W2943001835C12554922 @default.
- W2943001835 hasConceptScore W2943001835C135983454 @default.
- W2943001835 hasConceptScore W2943001835C151730666 @default.
- W2943001835 hasConceptScore W2943001835C171250308 @default.
- W2943001835 hasConceptScore W2943001835C178790620 @default.
- W2943001835 hasConceptScore W2943001835C181199279 @default.
- W2943001835 hasConceptScore W2943001835C185592680 @default.
- W2943001835 hasConceptScore W2943001835C190062978 @default.
- W2943001835 hasConceptScore W2943001835C192562407 @default.
- W2943001835 hasConceptScore W2943001835C2775925850 @default.
- W2943001835 hasConceptScore W2943001835C2776929087 @default.
- W2943001835 hasConceptScore W2943001835C2779281246 @default.
- W2943001835 hasConceptScore W2943001835C2779343474 @default.
- W2943001835 hasConceptScore W2943001835C2779820397 @default.
- W2943001835 hasConceptScore W2943001835C39944091 @default.
- W2943001835 hasConceptScore W2943001835C41625074 @default.
- W2943001835 hasConceptScore W2943001835C54009773 @default.
- W2943001835 hasConceptScore W2943001835C55493867 @default.
- W2943001835 hasConceptScore W2943001835C86803240 @default.
- W2943001835 hasConceptScore W2943001835C95444343 @default.
- W2943001835 hasConceptScore W2943001835C98539663 @default.
- W2943001835 hasLocation W29430018351 @default.
- W2943001835 hasOpenAccess W2943001835 @default.
- W2943001835 hasPrimaryLocation W29430018351 @default.
- W2943001835 hasRelatedWork W1601742916 @default.
- W2943001835 hasRelatedWork W1965114371 @default.
- W2943001835 hasRelatedWork W1981009270 @default.
- W2943001835 hasRelatedWork W2019112006 @default.
- W2943001835 hasRelatedWork W2080971086 @default.
- W2943001835 hasRelatedWork W2110500231 @default.
- W2943001835 hasRelatedWork W2168707500 @default.
- W2943001835 hasRelatedWork W2258905208 @default.
- W2943001835 hasRelatedWork W2442243993 @default.
- W2943001835 hasRelatedWork W2789330875 @default.
- W2943001835 hasRelatedWork W2802278228 @default.
- W2943001835 hasRelatedWork W2834603078 @default.
- W2943001835 hasRelatedWork W2940859099 @default.
- W2943001835 hasRelatedWork W2998166173 @default.
- W2943001835 hasRelatedWork W3003479630 @default.
- W2943001835 hasRelatedWork W3040406781 @default.
- W2943001835 hasRelatedWork W3125153862 @default.
- W2943001835 hasRelatedWork W3197187911 @default.
- W2943001835 hasRelatedWork W1823436221 @default.
- W2943001835 hasRelatedWork W2773764756 @default.
- W2943001835 isParatext "false" @default.
- W2943001835 isRetracted "false" @default.
- W2943001835 magId "2943001835" @default.
- W2943001835 workType "article" @default.