FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2943023851> ?p ?o ?g. }

• W2943023851 endingPage "108" @default.
• W2943023851 startingPage "98" @default.
• W2943023851 abstract "Human Herpes Virus-3 (Varicella Zoster Virus) causes Chickenpox in childhood and reactivates after decades of being latent to cause Herpes Zoster in adults. The aim of this study was to evaluate the in vitro antiviral potency on the leaves of Punica granatum L., Momordica charantia L., Andrographis paniculata Nees. and Melia azedarach L., against the Human Herpes Virus-3 isolated from Chickenpox and Zoster in comparison with acyclovir. Aqueous, ethanolic and aqueous ethanolic extracts were prepared from the chosen plant leaves by lyophilization process and subjected to in vitro cytotoxicity assay in HEp-2 cells followed by the in vitro antiviral evaluation against the clinical isolates of HHV-3 using post incubation assay. The structure of leaf chemicals were retrieved from protein data bank and in silico drug analysis was carried out through discovery studio targeting the protease of HHV-3.The drug likeliness and the ADMETSAR properties of the screened active phytochemicals were calculated. Aqueous extract from the leaves of Punica granatum L., exhibited potential antiviral activity against the HHV-3. The in silico docking results found that the phytochemicals of Punica granatum L., interacted on the active site of the HHV-3 protease. Aqueous extract from the leaves of Punica granatum L. was superior in exhibiting its antiviral efficacy to HHV-3 whose in vitro activity was comparable with acyclovir. As the leaf phytochemicals interacted with the HHV-3 protease, the antiviral activity of the Punica granatum L., leaves may interfere with the capsid assembly of the HHV-3." @default.
• W2943023851 created "2019-05-09" @default.
• W2943023851 creator A5019445593 @default.
• W2943023851 creator A5052503987 @default.
• W2943023851 creator A5082993817 @default.
• W2943023851 creator A5088830064 @default.
• W2943023851 date "2019-06-01" @default.
• W2943023851 modified "2023-09-30" @default.
• W2943023851 title "Antiviral study on Punica granatum L., Momordica charantia L., Andrographis paniculata Nees, and Melia azedarach L., to Human Herpes Virus-3" @default.
• W2943023851 cites W1768160923 @default.
• W2943023851 cites W1969487400 @default.
• W2943023851 cites W1971062326 @default.
• W2943023851 cites W1985570405 @default.
• W2943023851 cites W1986240377 @default.
• W2943023851 cites W1990034478 @default.
• W2943023851 cites W1993989671 @default.
• W2943023851 cites W2006114695 @default.
• W2943023851 cites W2010047580 @default.
• W2943023851 cites W2014858249 @default.
• W2943023851 cites W2017686017 @default.
• W2943023851 cites W2022932736 @default.
• W2943023851 cites W2030252990 @default.
• W2943023851 cites W2039201336 @default.
• W2943023851 cites W2040801518 @default.
• W2943023851 cites W2041877140 @default.
• W2943023851 cites W2047449673 @default.
• W2943023851 cites W2048963924 @default.
• W2943023851 cites W2049029401 @default.
• W2943023851 cites W2060763754 @default.
• W2943023851 cites W2074364245 @default.
• W2943023851 cites W2082857130 @default.
• W2943023851 cites W2095043733 @default.
• W2943023851 cites W2097376841 @default.
• W2943023851 cites W2107632949 @default.
• W2943023851 cites W2109235060 @default.
• W2943023851 cites W2109950770 @default.
• W2943023851 cites W2110593918 @default.
• W2943023851 cites W2130013364 @default.
• W2943023851 cites W2139639819 @default.
• W2943023851 cites W2143070532 @default.
• W2943023851 cites W2152313153 @default.
• W2943023851 cites W2160423182 @default.
• W2943023851 cites W2163705520 @default.
• W2943023851 cites W2256756668 @default.
• W2943023851 cites W2315316704 @default.
• W2943023851 cites W4240627419 @default.
• W2943023851 cites W4366956072 @default.
• W2943023851 doi "https://doi.org/10.1016/j.eujim.2019.04.008" @default.
• W2943023851 hasPublicationYear "2019" @default.
• W2943023851 type Work @default.
• W2943023851 sameAs 2943023851 @default.
• W2943023851 citedByCount "20" @default.
• W2943023851 countsByYear W29430238512020 @default.
• W2943023851 countsByYear W29430238512021 @default.
• W2943023851 countsByYear W29430238512022 @default.
• W2943023851 countsByYear W29430238512023 @default.
• W2943023851 crossrefType "journal-article" @default.
• W2943023851 hasAuthorship W2943023851A5019445593 @default.
• W2943023851 hasAuthorship W2943023851A5052503987 @default.
• W2943023851 hasAuthorship W2943023851A5082993817 @default.
• W2943023851 hasAuthorship W2943023851A5088830064 @default.
• W2943023851 hasConcept C142724271 @default.
• W2943023851 hasConcept C159047783 @default.
• W2943023851 hasConcept C181199279 @default.
• W2943023851 hasConcept C195475562 @default.
• W2943023851 hasConcept C204787440 @default.
• W2943023851 hasConcept C2522874641 @default.
• W2943023851 hasConcept C2776714187 @default.
• W2943023851 hasConcept C2777970627 @default.
• W2943023851 hasConcept C2778686829 @default.
• W2943023851 hasConcept C2779158651 @default.
• W2943023851 hasConcept C2780125355 @default.
• W2943023851 hasConcept C2780899423 @default.
• W2943023851 hasConcept C55493867 @default.
• W2943023851 hasConcept C556039675 @default.
• W2943023851 hasConcept C71924100 @default.
• W2943023851 hasConcept C86803240 @default.
• W2943023851 hasConceptScore W2943023851C142724271 @default.
• W2943023851 hasConceptScore W2943023851C159047783 @default.
• W2943023851 hasConceptScore W2943023851C181199279 @default.
• W2943023851 hasConceptScore W2943023851C195475562 @default.
• W2943023851 hasConceptScore W2943023851C204787440 @default.
• W2943023851 hasConceptScore W2943023851C2522874641 @default.
• W2943023851 hasConceptScore W2943023851C2776714187 @default.
• W2943023851 hasConceptScore W2943023851C2777970627 @default.
• W2943023851 hasConceptScore W2943023851C2778686829 @default.
• W2943023851 hasConceptScore W2943023851C2779158651 @default.
• W2943023851 hasConceptScore W2943023851C2780125355 @default.
• W2943023851 hasConceptScore W2943023851C2780899423 @default.
• W2943023851 hasConceptScore W2943023851C55493867 @default.
• W2943023851 hasConceptScore W2943023851C556039675 @default.
• W2943023851 hasConceptScore W2943023851C71924100 @default.
• W2943023851 hasConceptScore W2943023851C86803240 @default.
• W2943023851 hasLocation W29430238511 @default.
• W2943023851 hasOpenAccess W2943023851 @default.
• W2943023851 hasPrimaryLocation W29430238511 @default.
• W2943023851 hasRelatedWork W2188394310 @default.
• W2943023851 hasRelatedWork W2590095110 @default.

• next