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- W2943248001 abstract "The cytoplasm of living cells is a complex structure formed by a fluid phase composed by water and small molecules and a second phase composed by the filaments of the cytoskeleton forming a viscoelastic gel. The interaction between the two phases gives rise to a poroviscoelastic structure which combines elastic and viscous responses to external stimuli. On the other hand, the cytoplasm is active, and molecular motors perform active stress. Different molecules regulate the activity of the motors. In the cytoplasm the biochemistry and the mechanics are interconnected, while motors and biochemical regulators are transported by flows in the two phases, the motors produce active stresses into the cytoskeleton and generate active flows. Here, we compare two active poroviscoelastic models with different viscoelastic properties, which can produce oscillations and the polarization of a living cell. The main features of the different mechanisms of pattern formation are studied by linear stability analysis of the homogeneous steady state and by numerical simulations." @default.
- W2943248001 created "2019-05-09" @default.
- W2943248001 creator A5068363272 @default.
- W2943248001 date "2019-01-01" @default.
- W2943248001 modified "2023-09-27" @default.
- W2943248001 title "Onset of Mechanochemical Pattern Formation in Poroviscoelastic Models of Active Cytoplasm" @default.
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- W2943248001 doi "https://doi.org/10.1007/978-3-030-16585-7_5" @default.
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