FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2943397111> ?p ?o ?g. }

• W2943397111 abstract "Abstract Development of efficient targeting nanomaterials is extremely challenging due to the nonspecific accumulation in immune tissues, such as the liver and the spleen. Ultrasmall nanoparticles (USNPs) could possess small molecule‐like in vivo pharmacokinetic profiles, coupled with integrated functions capacity, improving the molecular imaging efficiency, particularly in oncology. For nuclear imaging, radiometals are often incorporated into the structures of USNPs using chelator and chelator‐free strategies. However, the incorporated chelator may change the surface properties and in vivo behavior of UNSPs, while chelator‐free labeling strategies either involve complicated resynthesis or rely on the active properties of the metal ions. Herein, a novel chelator‐free and postsynthetic strategy for broad‐spectrum metal ion attachment is reported. The ultrasmall Ag 2 Se quantum dots (QDs) are developed with an active oxygen layer on the surface, allowing for facile incorporation of both active and inert metals with high labeling efficiency. The particles enable fluorescence, magnetic resonance imaging, and positron emission tomography (PET) trimodality imaging. After conjugation with targeting peptide, the probe yields a high tumor‐to‐muscle ratio of nine in PET imaging. Importantly, the QDs are predominantly excreted from body through the renal route within 12 h. This chelator‐free strategy opens an avenue for exploring broad‐spectrum radiometal isotope labeling and USNP‐based renal‐excreting imaging probes." @default.
• W2943397111 created "2019-05-09" @default.
• W2943397111 creator A5003578005 @default.
• W2943397111 creator A5018249388 @default.
• W2943397111 creator A5022031408 @default.
• W2943397111 creator A5038506360 @default.
• W2943397111 creator A5040979952 @default.
• W2943397111 creator A5052823796 @default.
• W2943397111 creator A5056376298 @default.
• W2943397111 creator A5073508811 @default.
• W2943397111 creator A5079974007 @default.
• W2943397111 creator A5081480904 @default.
• W2943397111 creator A5084501114 @default.
• W2943397111 creator A5088055918 @default.
• W2943397111 date "2019-04-30" @default.
• W2943397111 modified "2023-10-14" @default.
• W2943397111 title "Ultrasmall Quantum Dots with Broad‐Spectrum Metal Doping Ability for Trimodal Molecular Imaging" @default.
• W2943397111 cites W1965097716 @default.
• W2943397111 cites W1990845976 @default.
• W2943397111 cites W1992612475 @default.
• W2943397111 cites W1996672400 @default.
• W2943397111 cites W2002015794 @default.
• W2943397111 cites W2026762108 @default.
• W2943397111 cites W2028172671 @default.
• W2943397111 cites W2056069790 @default.
• W2943397111 cites W2060238699 @default.
• W2943397111 cites W2069187748 @default.
• W2943397111 cites W2072854067 @default.
• W2943397111 cites W2081813848 @default.
• W2943397111 cites W2085560810 @default.
• W2943397111 cites W2094415778 @default.
• W2943397111 cites W2096293149 @default.
• W2943397111 cites W2110634891 @default.
• W2943397111 cites W2112101570 @default.
• W2943397111 cites W2115762222 @default.
• W2943397111 cites W2118969052 @default.
• W2943397111 cites W2126346850 @default.
• W2943397111 cites W2129425796 @default.
• W2943397111 cites W2136693699 @default.
• W2943397111 cites W2144780370 @default.
• W2943397111 cites W2155977076 @default.
• W2943397111 cites W2170959394 @default.
• W2943397111 cites W2223071637 @default.
• W2943397111 cites W2264996468 @default.
• W2943397111 cites W2305040764 @default.
• W2943397111 cites W2318093586 @default.
• W2943397111 cites W2322098576 @default.
• W2943397111 cites W2328483829 @default.
• W2943397111 cites W2329693581 @default.
• W2943397111 cites W2518071875 @default.
• W2943397111 cites W2569658671 @default.
• W2943397111 cites W2573995939 @default.
• W2943397111 cites W2616344061 @default.
• W2943397111 cites W2745942738 @default.
• W2943397111 cites W2755429536 @default.
• W2943397111 cites W2761533149 @default.
• W2943397111 cites W2765209067 @default.
• W2943397111 cites W2767074976 @default.
• W2943397111 cites W2773668357 @default.
• W2943397111 cites W2789871476 @default.
• W2943397111 cites W2809753664 @default.
• W2943397111 cites W2886166918 @default.
• W2943397111 cites W2886949120 @default.
• W2943397111 cites W2895816821 @default.
• W2943397111 doi "https://doi.org/10.1002/adfm.201901671" @default.
• W2943397111 hasPublicationYear "2019" @default.
• W2943397111 type Work @default.
• W2943397111 sameAs 2943397111 @default.
• W2943397111 citedByCount "15" @default.
• W2943397111 countsByYear W29433971112019 @default.
• W2943397111 countsByYear W29433971112020 @default.
• W2943397111 countsByYear W29433971112021 @default.
• W2943397111 countsByYear W29433971112022 @default.
• W2943397111 countsByYear W29433971112023 @default.
• W2943397111 crossrefType "journal-article" @default.
• W2943397111 hasAuthorship W2943397111A5003578005 @default.
• W2943397111 hasAuthorship W2943397111A5018249388 @default.
• W2943397111 hasAuthorship W2943397111A5022031408 @default.
• W2943397111 hasAuthorship W2943397111A5038506360 @default.
• W2943397111 hasAuthorship W2943397111A5040979952 @default.
• W2943397111 hasAuthorship W2943397111A5052823796 @default.
• W2943397111 hasAuthorship W2943397111A5056376298 @default.
• W2943397111 hasAuthorship W2943397111A5073508811 @default.
• W2943397111 hasAuthorship W2943397111A5079974007 @default.
• W2943397111 hasAuthorship W2943397111A5081480904 @default.
• W2943397111 hasAuthorship W2943397111A5084501114 @default.
• W2943397111 hasAuthorship W2943397111A5088055918 @default.
• W2943397111 hasConcept C120665830 @default.
• W2943397111 hasConcept C121332964 @default.
• W2943397111 hasConcept C124657808 @default.
• W2943397111 hasConcept C12554922 @default.
• W2943397111 hasConcept C126838900 @default.
• W2943397111 hasConcept C136339569 @default.
• W2943397111 hasConcept C138631740 @default.
• W2943397111 hasConcept C143409427 @default.
• W2943397111 hasConcept C150903083 @default.
• W2943397111 hasConcept C171250308 @default.
• W2943397111 hasConcept C191897082 @default.
• W2943397111 hasConcept C192562407 @default.
• W2943397111 hasConcept C197404232 @default.

• next