Matches in SemOpenAlex for { <https://semopenalex.org/work/W2943426969> ?p ?o ?g. }
- W2943426969 endingPage "89" @default.
- W2943426969 startingPage "83" @default.
- W2943426969 abstract "Non-functioning pituitary adenomas (NFPA) are prevalent pituitary neoplasms. Because they do not present with hormonal hypersecretion, there is no marker that indicates regrowth or recurrence, as in other adenomas. Evaluate the immunohistochemical expression of PTTG, CD105 and Ki-67 and their relationships with age, gender, invasiveness, hormonal expression and regrowth or recurrence in the follow-up of NFPA operated and not submitted to radiotherapy. Included 56 patients submitted to transsphenoidal surgery. Clinical data were obtained from medical records. The invasion degree was obtained by Hardy's classification. Mean age 55 ± 13.6 years, 62.5% men and 68% invasive. Lesion persistence was present in 62.2% and regrowth in 35.7%. The recurrence-free survival rate was 94.5%, 75.4% and 69.1% (1, 2 and 3 years). No patient presented recurrence. The PTTG was positive in 55.3%, with statistically significant relationship with invasiveness, age and female gender, without relation to regrowth. The microvascular density showed statistically significant relationship with male gender, negative correlation with PTTG (r = −0.434, p = 0.001), and no relation with invasiveness and regrowth. The Ki-67 showed statistically significant relationship with age, tendency towards regrowth (p = 0.054) and, with no relation to invasiveness. It is suggested that PTTG can be used as a prognostic marker in NFPA." @default.
- W2943426969 created "2019-05-09" @default.
- W2943426969 creator A5003751974 @default.
- W2943426969 creator A5023388723 @default.
- W2943426969 creator A5036776381 @default.
- W2943426969 creator A5041617088 @default.
- W2943426969 creator A5060740074 @default.
- W2943426969 creator A5065448751 @default.
- W2943426969 creator A5079803285 @default.
- W2943426969 creator A5081839174 @default.
- W2943426969 creator A5091421075 @default.
- W2943426969 date "2019-08-01" @default.
- W2943426969 modified "2023-09-25" @default.
- W2943426969 title "PTTG overexpression in non-functioning pituitary adenomas: Correlation with invasiveness, female gender and younger age" @default.
- W2943426969 cites W1965048531 @default.
- W2943426969 cites W1967695487 @default.
- W2943426969 cites W1969995414 @default.
- W2943426969 cites W1974816487 @default.
- W2943426969 cites W1975957264 @default.
- W2943426969 cites W1978823557 @default.
- W2943426969 cites W1981793762 @default.
- W2943426969 cites W1993095991 @default.
- W2943426969 cites W1993968891 @default.
- W2943426969 cites W2014360334 @default.
- W2943426969 cites W2034415389 @default.
- W2943426969 cites W2035559509 @default.
- W2943426969 cites W2039342000 @default.
- W2943426969 cites W2042291531 @default.
- W2943426969 cites W2051091626 @default.
- W2943426969 cites W2051819196 @default.
- W2943426969 cites W2055879869 @default.
- W2943426969 cites W2058129344 @default.
- W2943426969 cites W2058487665 @default.
- W2943426969 cites W2064297621 @default.
- W2943426969 cites W2065840495 @default.
- W2943426969 cites W2076058111 @default.
- W2943426969 cites W2081795374 @default.
- W2943426969 cites W2082110547 @default.
- W2943426969 cites W2090195782 @default.
- W2943426969 cites W2097585410 @default.
- W2943426969 cites W2103896787 @default.
- W2943426969 cites W2104175834 @default.
- W2943426969 cites W2106350386 @default.
- W2943426969 cites W2116509464 @default.
- W2943426969 cites W2124982499 @default.
- W2943426969 cites W2131388016 @default.
- W2943426969 cites W2134705914 @default.
- W2943426969 cites W2140586374 @default.
- W2943426969 cites W2141787663 @default.
- W2943426969 cites W2146513771 @default.
- W2943426969 cites W2150362274 @default.
- W2943426969 cites W2154536753 @default.
- W2943426969 cites W2157863718 @default.
- W2943426969 cites W2166310672 @default.
- W2943426969 cites W2171593182 @default.
- W2943426969 cites W2203716661 @default.
- W2943426969 cites W2210318695 @default.
- W2943426969 cites W2265548632 @default.
- W2943426969 cites W226609814 @default.
- W2943426969 cites W2268520310 @default.
- W2943426969 cites W2318561906 @default.
- W2943426969 cites W2338823688 @default.
- W2943426969 cites W2339725387 @default.
- W2943426969 cites W2356869450 @default.
- W2943426969 cites W2593349611 @default.
- W2943426969 cites W2599100067 @default.
- W2943426969 cites W2780353699 @default.
- W2943426969 cites W2780979925 @default.
- W2943426969 cites W2793619768 @default.
- W2943426969 cites W2794002252 @default.
- W2943426969 cites W319337662 @default.
- W2943426969 cites W4367435856 @default.
- W2943426969 cites W71229122 @default.
- W2943426969 doi "https://doi.org/10.1016/j.anndiagpath.2019.04.016" @default.
- W2943426969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31154064" @default.
- W2943426969 hasPublicationYear "2019" @default.
- W2943426969 type Work @default.
- W2943426969 sameAs 2943426969 @default.
- W2943426969 citedByCount "15" @default.
- W2943426969 countsByYear W29434269692019 @default.
- W2943426969 countsByYear W29434269692020 @default.
- W2943426969 countsByYear W29434269692021 @default.
- W2943426969 countsByYear W29434269692022 @default.
- W2943426969 crossrefType "journal-article" @default.
- W2943426969 hasAuthorship W2943426969A5003751974 @default.
- W2943426969 hasAuthorship W2943426969A5023388723 @default.
- W2943426969 hasAuthorship W2943426969A5036776381 @default.
- W2943426969 hasAuthorship W2943426969A5041617088 @default.
- W2943426969 hasAuthorship W2943426969A5060740074 @default.
- W2943426969 hasAuthorship W2943426969A5065448751 @default.
- W2943426969 hasAuthorship W2943426969A5079803285 @default.
- W2943426969 hasAuthorship W2943426969A5081839174 @default.
- W2943426969 hasAuthorship W2943426969A5091421075 @default.
- W2943426969 hasBestOaLocation W29434269691 @default.
- W2943426969 hasConcept C117220453 @default.
- W2943426969 hasConcept C126322002 @default.
- W2943426969 hasConcept C142724271 @default.
- W2943426969 hasConcept C143998085 @default.