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- W2943466042 abstract "Neonates are born with an immature immune system, which develops during the first stages of life. This early immaturity is more acute in preterm newborns. The aim of the present study was to set up a preterm rat model, in which representative biomarkers of innate and adaptive immunity maturation that could be promoted by certain dietary interventions are established. Throughout the study, the body weight was registered. To evaluate the functionality of the intestinal epithelial barrier, in vivo permeability to dextrans was measured and a histomorphometric study was performed. Furthermore, the blood cell count, phagocytic activity of blood leukocytes and plasmatic immunoglobulins (Ig) were determined. Preterm rats showed lower erythrocyte and platelet concentration but a higher count of leukocytes than the term rats. Although there were no changes in the granulocytes’ ability to phagocytize, preterm monocytes had lower phagocytic activity. Moreover, lower plasma IgG and IgM concentrations were detected in preterm rats compared to full-term rats, without affecting IgA. Finally, the intestinal study revealed lower permeability in preterm rats and reduced goblet cell size. Here, we characterized a premature rat model, with differential immune system biomarkers, as a useful tool for immunonutritional studies aimed at boosting the development of the immune system." @default.
- W2943466042 created "2019-05-09" @default.
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- W2943466042 date "2019-05-01" @default.
- W2943466042 modified "2023-10-18" @default.
- W2943466042 title "A Preterm Rat Model for Immunonutritional Studies" @default.
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- W2943466042 cites W1972131349 @default.
- W2943466042 cites W1973976214 @default.
- W2943466042 cites W1985216615 @default.
- W2943466042 cites W1986709953 @default.
- W2943466042 cites W1989287758 @default.
- W2943466042 cites W1993401546 @default.
- W2943466042 cites W1994121972 @default.
- W2943466042 cites W1994502124 @default.
- W2943466042 cites W2002813501 @default.
- W2943466042 cites W2005754624 @default.
- W2943466042 cites W2013129680 @default.
- W2943466042 cites W2014156095 @default.
- W2943466042 cites W2022121774 @default.
- W2943466042 cites W2025580438 @default.
- W2943466042 cites W2031231728 @default.
- W2943466042 cites W2035191173 @default.
- W2943466042 cites W2037146887 @default.
- W2943466042 cites W2043763161 @default.
- W2943466042 cites W2045372552 @default.
- W2943466042 cites W2045546162 @default.
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- W2943466042 doi "https://doi.org/10.3390/nu11050999" @default.
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