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• W2943597326 abstract "DNA has been well-known for its applications in programmable self-assembly of materials. Nonetheless, utility of DNA origami, which offers more opportunity to realize complicated operations, has been very limited. Here we report self-assembly of a biomolecular motor system, microtubule-kinesin mediated by DNA origami nanostructures. We demonstrate that a rodlike DNA origami motif facilitates self-assembly of microtubules into asters. A smooth-muscle like molecular contraction system has also been realized using the DNA origami in which self-assembled microtubules exhibited fast and dynamic contraction in the presence of kinesins through an energy dissipative process. This work provides potential nanotechnological applications of DNA and biomolecular motor proteins." @default.
• W2943597326 created "2019-05-09" @default.
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• W2943597326 date "2019-04-30" @default.
• W2943597326 modified "2023-10-14" @default.
• W2943597326 title "Artificial Smooth Muscle Model Composed of Hierarchically Ordered Microtubule Asters Mediated by DNA Origami Nanostructures" @default.
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• W2943597326 doi "https://doi.org/10.1021/acs.nanolett.9b01201" @default.
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