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• W2943669081 endingPage "2885" @default.
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• W2943669081 abstract "Summary Green turtles are endangered marine herbivorous hindgut fermenters that contribute to a variety of marine ecosystems. Debilitated turtles are often rehabilitated in turtle hospitals. Since accurate diagnosis of disease is difficult, broad‐spectrum antibiotics are routinely used as a general treatment, potentially causing collateral damage to the gut microbiome of the patient. Here, we evaluated the concept of the application of bacteriophage (phages) to eliminate targeted intestinal bacteria as an alternative to a broad‐spectrum antibiotic (enrofloxacin) in clinically healthy, captive green turtles. Additionally, the impact of a broad‐spectrum antibiotic (enrofloxacin) and phage therapy on the gut bacterial communities of green turtles was evaluated. Gut bacterial communities in faecal samples were analysed by sequencing the V1‐V3 regions of the bacterial 16S rRNA. Bacteria‐specific phage cocktails significantly ( P < 0.05) reduced targeted Acinetobacter in phage‐treated turtles during the therapy. Compared to control, no significant difference was observed in the bacterial diversity and compositions in phage‐treated turtles. In contrast, bacterial diversity was significantly ( P < 0.05) reduced in antibiotic‐treated turtles at day 15 and throughout the trial. The alteration in the bacterial microbiota of antibiotic‐treated turtles was largely due to an increase in abundance of Gram‐positive Firmicutes and a concurrent decrease in Gram‐negative Bacteroidetes, Proteobacteria and Verrucomicrobia. Additionally, we observed the relative abundance of several bacteria at lower taxonomic level was much less affected by phages than by antibiotics. These data offer the proof of concept of phage therapy to manipulate transient as well as indigenous bacterial flora in gut‐related dysbiosis of turtles." @default.
• W2943669081 created "2019-05-09" @default.
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• W2943669081 date "2019-05-15" @default.
• W2943669081 modified "2023-09-27" @default.
• W2943669081 title "Bacteriophage versus antibiotic therapy on gut bacterial communities of juvenile green turtle,<i>Chelonia mydas</i>" @default.
• W2943669081 cites W1514768507 @default.
• W2943669081 cites W1551444774 @default.
• W2943669081 cites W1560705037 @default.
• W2943669081 cites W1726803438 @default.
• W2943669081 cites W1825904294 @default.
• W2943669081 cites W1908807136 @default.
• W2943669081 cites W1934624334 @default.
• W2943669081 cites W1966423019 @default.
• W2943669081 cites W1967821667 @default.
• W2943669081 cites W1973192023 @default.
• W2943669081 cites W1974394752 @default.
• W2943669081 cites W1976025175 @default.
• W2943669081 cites W1981147988 @default.
• W2943669081 cites W1981196703 @default.
• W2943669081 cites W1982786943 @default.
• W2943669081 cites W1991604124 @default.
• W2943669081 cites W1992196067 @default.
• W2943669081 cites W1996606716 @default.
• W2943669081 cites W2008497935 @default.
• W2943669081 cites W2011223551 @default.
• W2943669081 cites W2012606594 @default.
• W2943669081 cites W2013067182 @default.
• W2943669081 cites W2017136623 @default.
• W2943669081 cites W2029702111 @default.
• W2943669081 cites W2032112360 @default.
• W2943669081 cites W2037894695 @default.
• W2943669081 cites W2043442946 @default.
• W2943669081 cites W2058362335 @default.
• W2943669081 cites W2059494851 @default.
• W2943669081 cites W2068301725 @default.
• W2943669081 cites W2069178790 @default.
• W2943669081 cites W2070190014 @default.
• W2943669081 cites W2070879762 @default.
• W2943669081 cites W2072970694 @default.
• W2943669081 cites W2078365477 @default.
• W2943669081 cites W2091220627 @default.
• W2943669081 cites W2096891806 @default.
• W2943669081 cites W2097762285 @default.
• W2943669081 cites W2098132478 @default.
• W2943669081 cites W2099119185 @default.
• W2943669081 cites W2100096695 @default.
• W2943669081 cites W2100229346 @default.
• W2943669081 cites W2110065044 @default.
• W2943669081 cites W2116613551 @default.
• W2943669081 cites W2117840807 @default.
• W2943669081 cites W2125174161 @default.
• W2943669081 cites W2132230729 @default.
• W2943669081 cites W2133211145 @default.
• W2943669081 cites W2136879569 @default.
• W2943669081 cites W2138007699 @default.
• W2943669081 cites W2141201132 @default.
• W2943669081 cites W2145158133 @default.
• W2943669081 cites W2146624345 @default.
• W2943669081 cites W2147618390 @default.
• W2943669081 cites W2163961385 @default.
• W2943669081 cites W2166562121 @default.
• W2943669081 cites W2172146785 @default.
• W2943669081 cites W2175551680 @default.
• W2943669081 cites W2214253644 @default.
• W2943669081 cites W2296724767 @default.
• W2943669081 cites W2317403532 @default.
• W2943669081 cites W2317727866 @default.
• W2943669081 cites W2336105168 @default.
• W2943669081 cites W2339765445 @default.
• W2943669081 cites W2340070942 @default.
• W2943669081 cites W2346423776 @default.
• W2943669081 cites W2468459151 @default.
• W2943669081 cites W2546762021 @default.
• W2943669081 cites W2566219535 @default.
• W2943669081 cites W2570971660 @default.
• W2943669081 cites W2597558540 @default.
• W2943669081 cites W2610443309 @default.
• W2943669081 cites W2612510556 @default.
• W2943669081 cites W2644133316 @default.
• W2943669081 cites W2759155300 @default.
• W2943669081 cites W2774600610 @default.
• W2943669081 cites W2902734486 @default.
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• W2943669081 doi "https://doi.org/10.1111/1462-2920.14644" @default.
• W2943669081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31037801" @default.
• W2943669081 hasPublicationYear "2019" @default.
• W2943669081 type Work @default.
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