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• W2943897180 abstract "Cardiovascular diseases represent the main cause of comorbidly in chronic kidney disease (CKD) patients, with a 7% incidence in atrial fibrillation (AF) in end-stage renal disease (ESRD) patients. Until recently, prophylactic treatment of atrial fibrillation complications (such as thromboembolism) was mainly based on vitamin K antagonists (VKA) or heparin. In the last years, direct oral anticoagulants (DOACs) have been made available; however, their renal clearance limits their use on patients with severe renal impairment (eGFR <15 mL/min). Among DOACs, Rivaroxaban, a factor X-activated (Xa) inhibitor, shows good renal profile and it can be used in CKD patients up to stage 4 as well as in ESRD patients (at the moment only in North America and Canada). (Cardionephrology)" @default.
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• W2943897180 date "2019-03-01" @default.
• W2943897180 modified "2023-09-23" @default.
• W2943897180 title "Rivaroxaban e malattia renale cronica: evidenze dal presente e prospettive future" @default.
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• W2943897180 doi "https://doi.org/10.1177/0394936219836652" @default.
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