Matches in SemOpenAlex for { <https://semopenalex.org/work/W2943955392> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2943955392 endingPage "107" @default.
- W2943955392 startingPage "102" @default.
- W2943955392 abstract "Objectives: To explore the role of the growth of new nerves (neo-neurogenesis) in the tumorogenesis of squamous cell carcinoma of tongue. Materials and Methods: 10 formalin-fixed specimens were gained from patients diagnosed with tongue squamous cell carcinoma. Animal models were made by subcutaneous injection in the dorsal midline with Tca-8113 cell line. Mice were sacrificed 2, 4, 6 weeks after cell injection, and tumor tissues were fixed in 4% paraformaldehyde, embedded in paraffin, sectioned. Detection of neo-neurogenesis was stained by Neurofila-ment-L antibody (NF-L) using immunohistochemistry method (IHC) in biopsy from both human body and animal model. Results: IHC staining of NF-L is positive in all 10 paraffins of tongue squamous cell carcinoma sections which suggest that newly formed nerves are observed in tumor microenvironment. NF-L staining is also positive in the paraffins from animal models indicating that the tongue cancer recruits newly formed nerves in its tumorogenesis. Conclusions: Tumor neo-neurogenesis may play an important role in the pathogenesis and development of tongue cancer. From a therapeutic perspective, further studies on the topic may provide new clinical opportunity." @default.
- W2943955392 created "2019-05-16" @default.
- W2943955392 creator A5066240164 @default.
- W2943955392 creator A5074526184 @default.
- W2943955392 date "2019-01-01" @default.
- W2943955392 modified "2023-09-26" @default.
- W2943955392 title "Neoneurogenesis in Squamous Cell Carcinoma of Tongue: A New Mechanism for Its Development" @default.
- W2943955392 cites W1532654778 @default.
- W2943955392 cites W1649549633 @default.
- W2943955392 cites W1967405323 @default.
- W2943955392 cites W2015670731 @default.
- W2943955392 cites W2034401564 @default.
- W2943955392 cites W2035406273 @default.
- W2943955392 cites W2049959255 @default.
- W2943955392 cites W2078787213 @default.
- W2943955392 cites W2113774043 @default.
- W2943955392 cites W2117692326 @default.
- W2943955392 cites W2128366974 @default.
- W2943955392 cites W2138699024 @default.
- W2943955392 cites W2140809915 @default.
- W2943955392 cites W2765161542 @default.
- W2943955392 doi "https://doi.org/10.4236/ojst.2019.95011" @default.
- W2943955392 hasPublicationYear "2019" @default.
- W2943955392 type Work @default.
- W2943955392 sameAs 2943955392 @default.
- W2943955392 citedByCount "1" @default.
- W2943955392 countsByYear W29439553922021 @default.
- W2943955392 crossrefType "journal-article" @default.
- W2943955392 hasAuthorship W2943955392A5066240164 @default.
- W2943955392 hasAuthorship W2943955392A5074526184 @default.
- W2943955392 hasBestOaLocation W29439553921 @default.
- W2943955392 hasConcept C121608353 @default.
- W2943955392 hasConcept C126322002 @default.
- W2943955392 hasConcept C142724271 @default.
- W2943955392 hasConcept C169760540 @default.
- W2943955392 hasConcept C204232928 @default.
- W2943955392 hasConcept C2775934546 @default.
- W2943955392 hasConcept C2778723968 @default.
- W2943955392 hasConcept C2779744641 @default.
- W2943955392 hasConcept C3019992690 @default.
- W2943955392 hasConcept C4746552 @default.
- W2943955392 hasConcept C71924100 @default.
- W2943955392 hasConcept C86803240 @default.
- W2943955392 hasConceptScore W2943955392C121608353 @default.
- W2943955392 hasConceptScore W2943955392C126322002 @default.
- W2943955392 hasConceptScore W2943955392C142724271 @default.
- W2943955392 hasConceptScore W2943955392C169760540 @default.
- W2943955392 hasConceptScore W2943955392C204232928 @default.
- W2943955392 hasConceptScore W2943955392C2775934546 @default.
- W2943955392 hasConceptScore W2943955392C2778723968 @default.
- W2943955392 hasConceptScore W2943955392C2779744641 @default.
- W2943955392 hasConceptScore W2943955392C3019992690 @default.
- W2943955392 hasConceptScore W2943955392C4746552 @default.
- W2943955392 hasConceptScore W2943955392C71924100 @default.
- W2943955392 hasConceptScore W2943955392C86803240 @default.
- W2943955392 hasIssue "05" @default.
- W2943955392 hasLocation W29439553921 @default.
- W2943955392 hasOpenAccess W2943955392 @default.
- W2943955392 hasPrimaryLocation W29439553921 @default.
- W2943955392 hasRelatedWork W124883000 @default.
- W2943955392 hasRelatedWork W2040271201 @default.
- W2943955392 hasRelatedWork W2330693733 @default.
- W2943955392 hasRelatedWork W2382738577 @default.
- W2943955392 hasRelatedWork W2616033432 @default.
- W2943955392 hasRelatedWork W2728479721 @default.
- W2943955392 hasRelatedWork W2896999981 @default.
- W2943955392 hasRelatedWork W3011259429 @default.
- W2943955392 hasRelatedWork W4292688661 @default.
- W2943955392 hasRelatedWork W4206846024 @default.
- W2943955392 hasVolume "09" @default.
- W2943955392 isParatext "false" @default.
- W2943955392 isRetracted "false" @default.
- W2943955392 magId "2943955392" @default.
- W2943955392 workType "article" @default.