FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2944108245> ?p ?o ?g. }

• W2944108245 endingPage "13" @default.
• W2944108245 startingPage "1" @default.
• W2944108245 abstract "Purpose. Irreversible electroporation (IRE) has been demonstrated to be a safe and effective method for locally advanced pancreatic cancer (LAPC). The aim of this study was to evaluate the immunomodulatory effect after IRE and to evaluate the prognostic value of variations of the immune parameters in LAPC patients after IRE. Methods. Peripheral blood samples of 34 patients were obtained preoperatively and on the third day (D3) and seventh day (D7) after IRE, respectively. The phenotypes of lymphocytes were analyzed by flow cytometry, and dynamic changes of serum levels of cytokines, complement, and immunoglobulin were assayed by enzyme-linked immunosorbent assay. Receiver operating characteristic (ROC) curve and concordance index (C-index) were used to compare the survival predictive ability. Results. There was a transitory decrease followed by a steady increase for CD4 + T cell, CD8 + T cell, NK cell, IL-2, C3, C4, and IgG while a reverse trend was detected for Treg cell, IL-6, and IL10 after IRE. The alteration of CD8 + T cell between D3 and D7 was identified as a prognostic factor for both overall survival (OS) and progression-free survival (PFS). The values of ROC curve (AUC) and C-indexes of the alteration of CD8 + T cell for OS and PFS were 0.816 and 0.773 and 0.816 and 0.639, respectively, which were larger than those of other immune or inflammation-based indexes. Conclusions. This study presented the first evidence of IRE-based immunomodulatory in patients with LAPC. The alteration of CD8 + T cell between D3 and D7 showed relatively good performance and could be used as an effective tool for prognostic evaluation for LAPC patients after IRE." @default.
• W2944108245 created "2019-05-16" @default.
• W2944108245 creator A5042241049 @default.
• W2944108245 creator A5055101832 @default.
• W2944108245 creator A5065199343 @default.
• W2944108245 creator A5071773009 @default.
• W2944108245 creator A5088392254 @default.
• W2944108245 date "2019-05-12" @default.
• W2944108245 modified "2023-10-16" @default.
• W2944108245 title "Immunomodulatory Effect after Irreversible Electroporation in Patients with Locally Advanced Pancreatic Cancer" @default.
• W2944108245 cites W1963637632 @default.
• W2944108245 cites W1982146826 @default.
• W2944108245 cites W1992768156 @default.
• W2944108245 cites W2009720434 @default.
• W2944108245 cites W2011379556 @default.
• W2944108245 cites W2024477013 @default.
• W2944108245 cites W2030847903 @default.
• W2944108245 cites W2039105461 @default.
• W2944108245 cites W2050575833 @default.
• W2944108245 cites W2115663098 @default.
• W2944108245 cites W2122041824 @default.
• W2944108245 cites W2136771120 @default.
• W2944108245 cites W2152387274 @default.
• W2944108245 cites W2206173668 @default.
• W2944108245 cites W2272984102 @default.
• W2944108245 cites W2275337389 @default.
• W2944108245 cites W2345822778 @default.
• W2944108245 cites W2413386818 @default.
• W2944108245 cites W2603992739 @default.
• W2944108245 cites W2757828780 @default.
• W2944108245 cites W2773278295 @default.
• W2944108245 cites W2801875753 @default.
• W2944108245 cites W2802187011 @default.
• W2944108245 cites W2886821451 @default.
• W2944108245 cites W2889646458 @default.
• W2944108245 cites W2897370023 @default.
• W2944108245 cites W2901746942 @default.
• W2944108245 cites W2903623792 @default.
• W2944108245 cites W2906815954 @default.
• W2944108245 cites W2907352725 @default.
• W2944108245 cites W2908965760 @default.
• W2944108245 cites W2909107489 @default.
• W2944108245 cites W2914128828 @default.
• W2944108245 cites W2914140263 @default.
• W2944108245 cites W2917772670 @default.
• W2944108245 doi "https://doi.org/10.1155/2019/9346017" @default.
• W2944108245 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6535893" @default.
• W2944108245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31214261" @default.
• W2944108245 hasPublicationYear "2019" @default.
• W2944108245 type Work @default.
• W2944108245 sameAs 2944108245 @default.
• W2944108245 citedByCount "34" @default.
• W2944108245 countsByYear W29441082452019 @default.
• W2944108245 countsByYear W29441082452020 @default.
• W2944108245 countsByYear W29441082452021 @default.
• W2944108245 countsByYear W29441082452022 @default.
• W2944108245 countsByYear W29441082452023 @default.
• W2944108245 crossrefType "journal-article" @default.
• W2944108245 hasAuthorship W2944108245A5042241049 @default.
• W2944108245 hasAuthorship W2944108245A5055101832 @default.
• W2944108245 hasAuthorship W2944108245A5065199343 @default.
• W2944108245 hasAuthorship W2944108245A5071773009 @default.
• W2944108245 hasAuthorship W2944108245A5088392254 @default.
• W2944108245 hasBestOaLocation W29441082451 @default.
• W2944108245 hasConcept C104317684 @default.
• W2944108245 hasConcept C121608353 @default.
• W2944108245 hasConcept C126322002 @default.
• W2944108245 hasConcept C143998085 @default.
• W2944108245 hasConcept C1491633281 @default.
• W2944108245 hasConcept C167672396 @default.
• W2944108245 hasConcept C186852380 @default.
• W2944108245 hasConcept C203014093 @default.
• W2944108245 hasConcept C2776090121 @default.
• W2944108245 hasConcept C2777701055 @default.
• W2944108245 hasConcept C2778716261 @default.
• W2944108245 hasConcept C2780210213 @default.
• W2944108245 hasConcept C502942594 @default.
• W2944108245 hasConcept C54355233 @default.
• W2944108245 hasConcept C553184892 @default.
• W2944108245 hasConcept C55493867 @default.
• W2944108245 hasConcept C58471807 @default.
• W2944108245 hasConcept C71924100 @default.
• W2944108245 hasConcept C86803240 @default.
• W2944108245 hasConcept C8891405 @default.
• W2944108245 hasConcept C90924648 @default.
• W2944108245 hasConceptScore W2944108245C104317684 @default.
• W2944108245 hasConceptScore W2944108245C121608353 @default.
• W2944108245 hasConceptScore W2944108245C126322002 @default.
• W2944108245 hasConceptScore W2944108245C143998085 @default.
• W2944108245 hasConceptScore W2944108245C1491633281 @default.
• W2944108245 hasConceptScore W2944108245C167672396 @default.
• W2944108245 hasConceptScore W2944108245C186852380 @default.
• W2944108245 hasConceptScore W2944108245C203014093 @default.
• W2944108245 hasConceptScore W2944108245C2776090121 @default.
• W2944108245 hasConceptScore W2944108245C2777701055 @default.
• W2944108245 hasConceptScore W2944108245C2778716261 @default.
• W2944108245 hasConceptScore W2944108245C2780210213 @default.
• W2944108245 hasConceptScore W2944108245C502942594 @default.

• next