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- W2944141566 abstract "Infection with Dengue Virus (DENV) causes the most prevalent arthropodborneviral disease worldwide. Since there are no antivirals available, there isan urgent medical need to discover novel therapeutic targets, implying a betterunderstanding of the cellular and molecular events governing DENV life cycle.Following infection, DENV induces a massive remodeling of the cytoplasmincluding the endoplasmic reticulum from which DENV replication factoriesare formed. In addition, DENV alters the morphology of other organelles suchas mitochondria to hijack their functions and to create a cellular environmentfavorable to viral replication. This review summarizes our current knowledgeabout the cytoplasmic remodeling activities of DENV." @default.
- W2944141566 created "2019-05-16" @default.
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- W2944141566 date "2016-01-01" @default.
- W2944141566 modified "2023-09-26" @default.
- W2944141566 title "The Remodeling of the Cytoplasm by Dengue Virus" @default.
- W2944141566 hasPublicationYear "2016" @default.
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