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- W2944148977 abstract "INTRODUCTION: A prospective study, conducted at Instituto Nacional de Perinatología (Mexico) from March to September 2018. Main objective was to evaluate the efficacy of misoprostol according to the International Federation of Gynecology and Obstetrics (FIGO) protocol 2017 in the management of first trimester miscarriages. METHODS: All patients first attending at urgency room diagnosed with first trimester miscarriages were given misoprostol according to FIGO protocol 2017. Via of administration varied according to physician. Efficacy was defined as complete uterine evacuation demonstrated by transvaginal scan on 7th day after misoprostol administration; if it was incomplete, an additional course was administrated. RESULTS: 76 patients were diagnosed with first trimester miscarriage and were treated based on FIGO 2017 protocol. Via of administration was vaginal 36.8%, buccal 30.2%, sublingual 21%, combined 9.2% and oral 2.6%. Main indications were 66.6% missed abortion, 2.5% incomplete abortion and 1.7% anembryonic pregnancy. Mean gestational age was 7.9 weeks. Main comorbidities were myomatosis 9.2%, diabetes mellitus 6.5%, human papillomavirus infection 5.2%, hypothyroidism 3.9%, recurrent gestational loss 2.6% and others 7.8%. Most frequent effects were 72.3% transvaginal bleeding plus pelvic pain, 11.8% isolated transvaginal bleeding, 2.6% slight pain pelvic and 13.1% were asymptomatic. About the efficacy, 93.4% had complete uterine evacuation with one course, 6% required a second course. One patient required manual vacuum aspiration after the second course. CONCLUSION: Use of misoprostol according to FIGO 2017 protocol is effective for treating first trimester miscarriage. Via of administration do not affect effectiveness. Patient should receive counselling, follow up and must sign inform consent." @default.
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- W2944148977 date "2019-05-01" @default.
- W2944148977 modified "2023-09-27" @default.
- W2944148977 title "Institutional Experience Using FIGO Protocol 2017 for First Trimester Miscarriages [28L]" @default.
- W2944148977 doi "https://doi.org/10.1097/01.aog/01.aog.0000559262.86900.6f" @default.
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