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- W2944212022 abstract "A vast literature is available on the health benefits and biological roles of n-3 PUFAs, and as only a minority of people regularly eats fatty fish, there is a huge development of foods enriched with these LC-PUFA (Calder, 2013). Increasing the EPA and DHA status can also be achieved by improving their bioavailability through the structuration of their carrier. Thus, pre-emulsification of marine oils has been shown to increase the absorption of EPA and DHA (Garaiova et al, 2007). Furthermore, modifications of the surface area of the lipid droplet, as the composition of the interface may impact the behavior of the emulsion during digestion and in fine the postprandial lipid metabolism. This study aimed to test the hypothesis that emulsion stable under gastric condition will release faster the absorbable lipids than an unstable one. Therefore, a blend of medium chain triacylglycerides and microalgae oils was emulsified with proteins as emulsifiers. The emulsions varied by the nature of the emulsifying proteins (whey proteins vs caseins) or the mean droplet diameter (> 1µm vs < 0.5µm). Microalgae oil served as source of DHA. The emulsions were submitted to an in vitro digestion to assess the overall extent of lipolysis as well as the LC-PUFA bioaccessibility. Six minipigs fitted with an arterial catheter were fed with the four different emulsions added to a standardized diet. Plasma samples were collected at different times after meal ingestion, and the evolution of fatty acids concentration determined and compared to the bioaccessibility results." @default.
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- W2944212022 date "2014-09-14" @default.
- W2944212022 modified "2023-09-27" @default.
- W2944212022 title "Bioaccessibility and bioavailability of DHA-rich lipids carried in protein-stabilized emulsions : comparison of in vivo and in vitro results." @default.
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