Matches in SemOpenAlex for { <https://semopenalex.org/work/W2944218682> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2944218682 endingPage "794" @default.
- W2944218682 startingPage "789" @default.
- W2944218682 abstract "Objective: We present a novel method for screening eye bank donor corneas using high definition optical coherence tomography (HD-OCT). This technology allows for the quantification of endothelial/Descemet membrane (En/DM) complex thickness ex vivo. Design: Prospective interventional study. Participants: Fifty-two corneal grafts from 27 donors were included in this study. Twenty additional control eyes and 11 eyes with Fuchs' endothelial corneal dystrophy were also evaluated for comparison. Methods: A custom built, high speed HD-OCT device (Envisu R2210, Bioptigen, Buffalo Grove, IL, USA) was used to obtain images, and custom-made graph-based segmentation software was used to automatically deconstruct corneal images into micro-layers. HD-OCT imaging was used to scan through the sealed sterile case of donor corneas stored in McCarey-Kaufman medium to image their En/DM complex through the center of the cornea. Results: This technology allowed for quantification of En/DM complex thickness in all donor corneas through the sealed sterile container used to transport graft tissue. Mean En/DM complex thickness of donor corneas was 17±4 μm. The difference between donor cornea En/DM thickness and that of control subjects (16±2 μm) was not statistically significant (p=0.3), suggesting that the transport container and media do not affect measurements. There was a significant difference between En/DM thickness of Fuchs' endothelial corneal dystrophy eyes (25±5 μm) and both donor corneas (p<0.0001) and control subjects (p<0.0001). Conclusions: We have described a new technique to measure En/DM complex thickness in eye bank donor corneas stored in a sealed sterile case. This may represent a novel adjunctive approach to screen corneal grafts for early endothelial disease." @default.
- W2944218682 created "2019-05-16" @default.
- W2944218682 creator A5009397846 @default.
- W2944218682 creator A5016495683 @default.
- W2944218682 creator A5024013683 @default.
- W2944218682 creator A5071031452 @default.
- W2944218682 creator A5073025568 @default.
- W2944218682 creator A5073080368 @default.
- W2944218682 creator A5076699585 @default.
- W2944218682 creator A5085027898 @default.
- W2944218682 date "2019-05-01" @default.
- W2944218682 modified "2023-09-23" @default.
- W2944218682 title "<p>Evaluation of endothelial/Descemet membrane complex of eye bank donor corneas using enhanced depth imaging optical coherence tomography</p>" @default.
- W2944218682 cites W1586606734 @default.
- W2944218682 cites W1980846287 @default.
- W2944218682 cites W2051336869 @default.
- W2944218682 cites W2051690312 @default.
- W2944218682 cites W2063171149 @default.
- W2944218682 cites W2066935182 @default.
- W2944218682 cites W2068546456 @default.
- W2944218682 cites W2074751593 @default.
- W2944218682 cites W2089706673 @default.
- W2944218682 cites W2149272307 @default.
- W2944218682 cites W2592473410 @default.
- W2944218682 cites W4298851931 @default.
- W2944218682 doi "https://doi.org/10.2147/opth.s185455" @default.
- W2944218682 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6514128" @default.
- W2944218682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31190724" @default.
- W2944218682 hasPublicationYear "2019" @default.
- W2944218682 type Work @default.
- W2944218682 sameAs 2944218682 @default.
- W2944218682 citedByCount "2" @default.
- W2944218682 countsByYear W29442186822020 @default.
- W2944218682 countsByYear W29442186822022 @default.
- W2944218682 crossrefType "journal-article" @default.
- W2944218682 hasAuthorship W2944218682A5009397846 @default.
- W2944218682 hasAuthorship W2944218682A5016495683 @default.
- W2944218682 hasAuthorship W2944218682A5024013683 @default.
- W2944218682 hasAuthorship W2944218682A5071031452 @default.
- W2944218682 hasAuthorship W2944218682A5073025568 @default.
- W2944218682 hasAuthorship W2944218682A5073080368 @default.
- W2944218682 hasAuthorship W2944218682A5076699585 @default.
- W2944218682 hasAuthorship W2944218682A5085027898 @default.
- W2944218682 hasBestOaLocation W29442186821 @default.
- W2944218682 hasConcept C118487528 @default.
- W2944218682 hasConcept C150903083 @default.
- W2944218682 hasConcept C207001950 @default.
- W2944218682 hasConcept C26291073 @default.
- W2944218682 hasConcept C2776882836 @default.
- W2944218682 hasConcept C2778818243 @default.
- W2944218682 hasConcept C2779353581 @default.
- W2944218682 hasConcept C3019694093 @default.
- W2944218682 hasConcept C71924100 @default.
- W2944218682 hasConcept C86803240 @default.
- W2944218682 hasConceptScore W2944218682C118487528 @default.
- W2944218682 hasConceptScore W2944218682C150903083 @default.
- W2944218682 hasConceptScore W2944218682C207001950 @default.
- W2944218682 hasConceptScore W2944218682C26291073 @default.
- W2944218682 hasConceptScore W2944218682C2776882836 @default.
- W2944218682 hasConceptScore W2944218682C2778818243 @default.
- W2944218682 hasConceptScore W2944218682C2779353581 @default.
- W2944218682 hasConceptScore W2944218682C3019694093 @default.
- W2944218682 hasConceptScore W2944218682C71924100 @default.
- W2944218682 hasConceptScore W2944218682C86803240 @default.
- W2944218682 hasLocation W29442186821 @default.
- W2944218682 hasLocation W29442186822 @default.
- W2944218682 hasLocation W29442186823 @default.
- W2944218682 hasLocation W29442186824 @default.
- W2944218682 hasOpenAccess W2944218682 @default.
- W2944218682 hasPrimaryLocation W29442186821 @default.
- W2944218682 hasRelatedWork W1997219368 @default.
- W2944218682 hasRelatedWork W2074352274 @default.
- W2944218682 hasRelatedWork W2289718678 @default.
- W2944218682 hasRelatedWork W2400153707 @default.
- W2944218682 hasRelatedWork W2944218682 @default.
- W2944218682 hasRelatedWork W2999136642 @default.
- W2944218682 hasRelatedWork W3014846783 @default.
- W2944218682 hasRelatedWork W3176270912 @default.
- W2944218682 hasRelatedWork W4213048818 @default.
- W2944218682 hasRelatedWork W4309844069 @default.
- W2944218682 hasVolume "Volume 13" @default.
- W2944218682 isParatext "false" @default.
- W2944218682 isRetracted "false" @default.
- W2944218682 magId "2944218682" @default.
- W2944218682 workType "article" @default.