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- W2944261154 abstract "Bismuth subsalicylate (BSS) is the active ingredient in over-the-counter antacid and antidiarrheal medications. Coagulopathy in the setting of acetylsalicylic acid toxicity is well documented but not in setting of bismuth subsalicylate overuse. We present a case report of coagulopathy from BSS poisoning in a patient with underlying cirrhosis. The patient's high prothrombin time suggests inhibition of vitamin K-dependent coagulation factors. The patient had decreased factor V activity, which is responsible for converting prothrombin to thrombin. Patients with cirrhosis often have hypoprothrombinemia which may be exacerbated by salicylate-induced coagulopathy. Given the widespread use of BSS products, physicians should recognize coagulopathy as a possible manifestation of toxicity especially in patients with underlying liver disease." @default.
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- W2944261154 date "2019-05-06" @default.
- W2944261154 modified "2023-09-26" @default.
- W2944261154 title "Bismuth Subsalicylate Coagulopathy in a Patient with Chronic Liver Disease" @default.
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- W2944261154 doi "https://doi.org/10.1007/s13181-019-00709-y" @default.
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