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- W2944280295 abstract "ABSTRACT The immune response to the hepatitis B virus (HBV) vaccine in newborns of hepatitis B e antigen (HBeAg)-positive or HBeAg-negative mothers is the subject of Huang et al. The authors report no correlation between the HBeAg status of the mothers/cord blood and the newborns immune response to the vaccine, but, unfortunately, draw unfounded conclusions regarding the tolerogenic potential of in utero exposure to HBeAg. In this reply, I address the possible influence of in utero exposure to the HBeAg, and briefly review other characteristics of the HBeAg, that may promote HBV chronicity. I argue that the function of HBeAg should no longer be considered “unknown” and that immunotolerance/immunomodulation represent the dominant functions of the HBeAg in viral–host interactions." @default.
- W2944280295 created "2019-05-16" @default.
- W2944280295 creator A5031097411 @default.
- W2944280295 date "2019-05-09" @default.
- W2944280295 modified "2023-09-25" @default.
- W2944280295 title "Is the function of the HBeAg really unknown?" @default.
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- W2944280295 doi "https://doi.org/10.1080/21645515.2019.1607132" @default.
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