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- W2944394188 abstract "Shiga toxin-producing Escherichia Coli (STEC) infections routinely run as a common gastroenteritis, but in many cases they may evolve towards hemolytic uremic syndrome (HUS). HUS is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Gut microorganisms have a fundamental impact on human physiology, because they modulate normal intestinal functions and play a pivotal role in influencing the local and systemic immune responses. Despite surveillance established in many countries and major progresses in the understanding of STEC-HUS mechanisms, no specific treatment is currently available. Targeting the gut microbiota could represent a new potential therapeutic strategy in STEC infection. In this paper, we reviewed the current knowledge about microbiota characteristics of patients with STEC infections, as well as in vitro and in vivo evidence of probiotic supplementation in managing STEC gastroenteritis and in HUS onset prevention." @default.
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- W2944394188 date "2019-05-12" @default.
- W2944394188 modified "2023-10-14" @default.
- W2944394188 title "Management of STEC Gastroenteritis: Is There a Role for Probiotics?" @default.
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- W2944394188 doi "https://doi.org/10.3390/ijerph16091649" @default.
- W2944394188 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6539596" @default.
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