FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2944475322> ?p ?o ?g. }

• W2944475322 endingPage "7" @default.
• W2944475322 startingPage "1" @default.
• W2944475322 abstract "Fluazuron is one of the newest veterinary antitick medicines. Belonging to the benzoylphenylureas group, its mechanism of action acts by the interference of the formation of the chitin of the tick, which is responsible for the hardening of its exoskeletons. In addition to taking care of the health of the animal so that it receives the medication in the doses and the correct form, it is important to analyze the safety of the operator. Reduced resistance to infectious disease was a well-documented consequence of primary and acquired immunodeficiencies, but a novel finding following xenobiotic exposure. The awareness of the consequences of altered immune function is the most likely outcome of inadvertent exposure. The human health implications of studies in which chemical exposure reduced resistance to infection drove an early focus on immunosuppression within the toxicology community. The main objective is to perform the evaluation by computational platforms and in cell culture, searching for data that can serve as a foundation for a better understanding of the toxic effects involved with the accidental contamination of Fluazuron and, thus, to assist the medical community and users to understand the risks inherent in its use. As far as we can determine in the literature, our work has unmistakably demonstrated that the Fluazuron can cause genotoxicity by probable chromatin rearrangement and immunodepleting by specific reduction of the CD8 T lymphocyte subpopulation, mediated by the decrease in gamma interferon production. Although the use of Fluazuron is a necessity for tick control and for cattle management, we must bear in mind that the imminent risks to its application exist. Careless use can damage the immune system which in turn carries a gigantic hazard by opening a door to diseases and pathogens and leaving us defenseless." @default.
• W2944475322 created "2019-05-16" @default.
• W2944475322 creator A5009760407 @default.
• W2944475322 creator A5012728345 @default.
• W2944475322 creator A5031805102 @default.
• W2944475322 creator A5042950031 @default.
• W2944475322 creator A5071044425 @default.
• W2944475322 creator A5084240614 @default.
• W2944475322 creator A5089337453 @default.
• W2944475322 creator A5090821520 @default.
• W2944475322 date "2019-05-07" @default.
• W2944475322 modified "2023-09-27" @default.
• W2944475322 title "Novel Acaricidal Drug Fluazuron Causes Immunotoxicity via Selective Depletion of Lymphocytes T CD8" @default.
• W2944475322 cites W1700855439 @default.
• W2944475322 cites W1812224319 @default.
• W2944475322 cites W1997872815 @default.
• W2944475322 cites W2024264346 @default.
• W2944475322 cites W2035002706 @default.
• W2944475322 cites W2064622661 @default.
• W2944475322 cites W2086959952 @default.
• W2944475322 cites W2092629964 @default.
• W2944475322 cites W2146980885 @default.
• W2944475322 cites W2147479689 @default.
• W2944475322 cites W2163910313 @default.
• W2944475322 cites W2177317049 @default.
• W2944475322 cites W2225235469 @default.
• W2944475322 cites W2579273803 @default.
• W2944475322 cites W2626742338 @default.
• W2944475322 cites W2676281669 @default.
• W2944475322 cites W4248953934 @default.
• W2944475322 cites W4255738197 @default.
• W2944475322 doi "https://doi.org/10.1155/2019/2815461" @default.
• W2944475322 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6530102" @default.
• W2944475322 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31205477" @default.
• W2944475322 hasPublicationYear "2019" @default.
• W2944475322 type Work @default.
• W2944475322 sameAs 2944475322 @default.
• W2944475322 citedByCount "3" @default.
• W2944475322 countsByYear W29444753222020 @default.
• W2944475322 countsByYear W29444753222022 @default.
• W2944475322 crossrefType "journal-article" @default.
• W2944475322 hasAuthorship W2944475322A5009760407 @default.
• W2944475322 hasAuthorship W2944475322A5012728345 @default.
• W2944475322 hasAuthorship W2944475322A5031805102 @default.
• W2944475322 hasAuthorship W2944475322A5042950031 @default.
• W2944475322 hasAuthorship W2944475322A5071044425 @default.
• W2944475322 hasAuthorship W2944475322A5084240614 @default.
• W2944475322 hasAuthorship W2944475322A5089337453 @default.
• W2944475322 hasAuthorship W2944475322A5090821520 @default.
• W2944475322 hasBestOaLocation W29444753221 @default.
• W2944475322 hasConcept C167672396 @default.
• W2944475322 hasConcept C203014093 @default.
• W2944475322 hasConcept C2780035454 @default.
• W2944475322 hasConcept C71924100 @default.
• W2944475322 hasConcept C86803240 @default.
• W2944475322 hasConcept C8891405 @default.
• W2944475322 hasConcept C98274493 @default.
• W2944475322 hasConceptScore W2944475322C167672396 @default.
• W2944475322 hasConceptScore W2944475322C203014093 @default.
• W2944475322 hasConceptScore W2944475322C2780035454 @default.
• W2944475322 hasConceptScore W2944475322C71924100 @default.
• W2944475322 hasConceptScore W2944475322C86803240 @default.
• W2944475322 hasConceptScore W2944475322C8891405 @default.
• W2944475322 hasConceptScore W2944475322C98274493 @default.
• W2944475322 hasLocation W29444753221 @default.
• W2944475322 hasLocation W29444753222 @default.
• W2944475322 hasLocation W29444753223 @default.
• W2944475322 hasLocation W29444753224 @default.
• W2944475322 hasLocation W29444753225 @default.
• W2944475322 hasOpenAccess W2944475322 @default.
• W2944475322 hasPrimaryLocation W29444753221 @default.
• W2944475322 hasRelatedWork W2050283198 @default.
• W2944475322 hasRelatedWork W2056075233 @default.
• W2944475322 hasRelatedWork W2056385328 @default.
• W2944475322 hasRelatedWork W2131198412 @default.
• W2944475322 hasRelatedWork W2220102944 @default.
• W2944475322 hasRelatedWork W2577548098 @default.
• W2944475322 hasRelatedWork W282825803 @default.
• W2944475322 hasRelatedWork W3031852375 @default.
• W2944475322 hasRelatedWork W3112940496 @default.
• W2944475322 hasRelatedWork W3187326853 @default.
• W2944475322 hasVolume "2019" @default.
• W2944475322 isParatext "false" @default.
• W2944475322 isRetracted "false" @default.
• W2944475322 magId "2944475322" @default.
• W2944475322 workType "article" @default.