Matches in SemOpenAlex for { <https://semopenalex.org/work/W2944516061> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2944516061 endingPage "1279" @default.
- W2944516061 startingPage "1267" @default.
- W2944516061 abstract "An ideal wound dressing should not only promote rapid hemostasis and wound healing but also have good biocompatibility, antimicrobial activities, and should mimic the skin's physiological function. In the present study, five O-quaternized chitosan (QAS-CS) materials with satisfactory antibacterial activity and no cytotoxicity were successfully synthesized. Furthermore, we reported the synthesis and characterization of the two novel composite nanofibrous scaffolds consisting of selfdeveloped collagen (COL), quaternary ammonium salt (QAS) or QAS-CS and polycaprolactone (PCL) or polyvinyl alcohol (PVA) with an electrospinning approach. The PCL/COL/QAS (PCQ3) and PVA/COL/QAS-CS (PCQC5) materials exhibited uniform, three-dimensional interconnected pore structure, high porosity, and large specific surface area, which can mimic the architecture and biological functions of the native extracellular matrix microenvironment and provide suitable conditions for cell adhesion, proliferation, and differentiation. The growth and proliferation of human immortalized epidermal (HaCaT) cells on PCQ3 and PCQC5 materials was good, and the result of blood compatibility and the skin irritant test indicated that the scaffolds had good blood compatibility and did not exhibit significant irritability. Importantly, PCQ3 and PCQC5 have notable effects on rapid hemostasis, antibacterial activity, and anti-inflammation, promote wound healing, and display other superior benefits in comparison to available products. Overall, PCQ3 and PCQC5 are proposed to be good candidates for skin tissue engineering applications and can be used on different types of wounds." @default.
- W2944516061 created "2019-05-16" @default.
- W2944516061 creator A5006579694 @default.
- W2944516061 creator A5025024898 @default.
- W2944516061 creator A5027949896 @default.
- W2944516061 creator A5036121570 @default.
- W2944516061 creator A5046078938 @default.
- W2944516061 creator A5076345724 @default.
- W2944516061 creator A5080314362 @default.
- W2944516061 date "2019-06-01" @default.
- W2944516061 modified "2023-09-26" @default.
- W2944516061 title "Functionalized Biomimetic Composite Nanfibrous Scaffolds with Antibacterial and Hemostatic Efficacy for Facilitating Wound Healing" @default.
- W2944516061 doi "https://doi.org/10.1166/jbn.2019.2756" @default.
- W2944516061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31072434" @default.
- W2944516061 hasPublicationYear "2019" @default.
- W2944516061 type Work @default.
- W2944516061 sameAs 2944516061 @default.
- W2944516061 citedByCount "24" @default.
- W2944516061 countsByYear W29445160612019 @default.
- W2944516061 countsByYear W29445160612020 @default.
- W2944516061 countsByYear W29445160612021 @default.
- W2944516061 countsByYear W29445160612022 @default.
- W2944516061 countsByYear W29445160612023 @default.
- W2944516061 crossrefType "journal-article" @default.
- W2944516061 hasAuthorship W2944516061A5006579694 @default.
- W2944516061 hasAuthorship W2944516061A5025024898 @default.
- W2944516061 hasAuthorship W2944516061A5027949896 @default.
- W2944516061 hasAuthorship W2944516061A5036121570 @default.
- W2944516061 hasAuthorship W2944516061A5046078938 @default.
- W2944516061 hasAuthorship W2944516061A5076345724 @default.
- W2944516061 hasAuthorship W2944516061A5080314362 @default.
- W2944516061 hasConcept C118995209 @default.
- W2944516061 hasConcept C136229726 @default.
- W2944516061 hasConcept C141071460 @default.
- W2944516061 hasConcept C144796933 @default.
- W2944516061 hasConcept C159985019 @default.
- W2944516061 hasConcept C178790620 @default.
- W2944516061 hasConcept C185592680 @default.
- W2944516061 hasConcept C189165786 @default.
- W2944516061 hasConcept C192562407 @default.
- W2944516061 hasConcept C202751555 @default.
- W2944516061 hasConcept C2777230088 @default.
- W2944516061 hasConcept C2778551929 @default.
- W2944516061 hasConcept C2778589496 @default.
- W2944516061 hasConcept C2779868350 @default.
- W2944516061 hasConcept C2780269544 @default.
- W2944516061 hasConcept C521977710 @default.
- W2944516061 hasConcept C55493867 @default.
- W2944516061 hasConcept C71924100 @default.
- W2944516061 hasConceptScore W2944516061C118995209 @default.
- W2944516061 hasConceptScore W2944516061C136229726 @default.
- W2944516061 hasConceptScore W2944516061C141071460 @default.
- W2944516061 hasConceptScore W2944516061C144796933 @default.
- W2944516061 hasConceptScore W2944516061C159985019 @default.
- W2944516061 hasConceptScore W2944516061C178790620 @default.
- W2944516061 hasConceptScore W2944516061C185592680 @default.
- W2944516061 hasConceptScore W2944516061C189165786 @default.
- W2944516061 hasConceptScore W2944516061C192562407 @default.
- W2944516061 hasConceptScore W2944516061C202751555 @default.
- W2944516061 hasConceptScore W2944516061C2777230088 @default.
- W2944516061 hasConceptScore W2944516061C2778551929 @default.
- W2944516061 hasConceptScore W2944516061C2778589496 @default.
- W2944516061 hasConceptScore W2944516061C2779868350 @default.
- W2944516061 hasConceptScore W2944516061C2780269544 @default.
- W2944516061 hasConceptScore W2944516061C521977710 @default.
- W2944516061 hasConceptScore W2944516061C55493867 @default.
- W2944516061 hasConceptScore W2944516061C71924100 @default.
- W2944516061 hasIssue "6" @default.
- W2944516061 hasLocation W29445160611 @default.
- W2944516061 hasLocation W29445160612 @default.
- W2944516061 hasOpenAccess W2944516061 @default.
- W2944516061 hasPrimaryLocation W29445160611 @default.
- W2944516061 hasRelatedWork W2323763977 @default.
- W2944516061 hasRelatedWork W2797246759 @default.
- W2944516061 hasRelatedWork W3011781978 @default.
- W2944516061 hasRelatedWork W3096556736 @default.
- W2944516061 hasRelatedWork W3117110844 @default.
- W2944516061 hasRelatedWork W3135498500 @default.
- W2944516061 hasRelatedWork W3157181406 @default.
- W2944516061 hasRelatedWork W3193506776 @default.
- W2944516061 hasRelatedWork W4292553524 @default.
- W2944516061 hasRelatedWork W4308959041 @default.
- W2944516061 hasVolume "15" @default.
- W2944516061 isParatext "false" @default.
- W2944516061 isRetracted "false" @default.
- W2944516061 magId "2944516061" @default.
- W2944516061 workType "article" @default.