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- W2944562819 abstract "Abstract Columnaris disease, caused by Flavobacterium columnare, is a serious bacterial disease responsible for causing devastating rates of mortality in numerous species of freshwater fish. This disease can cause mortalities of up to 100% within 24 h, leading to severe economic losses in the aquaculture industry. Notwithstanding the enormous impacts this disease can have, very little is known regarding the interaction between the host and bacterium. To gain a better understanding of the host immune response, an attempt has been made to study the sequential changes in innate immunity parameters of Catla catla, following bath challenge with F. columnare. The clinical signs in challenged fish included lethargy, respiratory distress, swimming near the water surface and accelerated opercular movements. Histopathological examination of the gills from infected fish revealed the presence of bacterial masses in the gills, fusion of secondary filaments and sloughing of epithelial cells with a consequential disruption to the gill architecture within 24–48 h. Importantly, some innate immunity parameters, namely the production of reactive oxygen species and nitric oxide as well as serum myeloperoxidase activity showed significant increases (p" @default.
- W2944562819 created "2019-05-16" @default.
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- W2944562819 date "2019-08-01" @default.
- W2944562819 modified "2023-10-17" @default.
- W2944562819 title "Modulation of the innate immune responses in Indian major carp, Catla catla following experimental infection with Flavobacterium columnare" @default.
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- W2944562819 doi "https://doi.org/10.1016/j.aquaculture.2019.05.015" @default.
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