FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2944599913> ?p ?o ?g. }

• W2944599913 endingPage "29" @default.
• W2944599913 startingPage "24" @default.
• W2944599913 abstract "Pulmonary tuberculosis caused by an intracellular pathogen, Mycobacterium tuberculosis continues to exist as a hazardous disease to human life globally. Genetic polymorphisms regulate resistance and susceptibility to tuberculosis. The C-type lectin receptor of family 4 member E (CLEC4E) confers protection against tuberculosis in laboratory animals but its function in influencing exposure or resistance to pulmonary tuberculosis (PTB) in humans remains obscure. We conducted this research to analyze the effects or concomitance of CLEC4E gene variations with susceptibility to pulmonary tuberculosis in a northern Chinese population. In this study, 202 participants with pulmonary tuberculosis and 214 controls without PTB were enrolled. Two single nucleotide polymorphisms (SNPs) for CLEC4E on chromosome 12 were selected with a minor allele frequency of >0.05. All the SNPs were genotyped using high resolution melting analysis–PCR. We estimated and compared two SNPs, rs10841845 and rs10841847. From our study findings, CLEC4E rs10841845 conferred protection against the development of pulmonary TB with a P value of <0.05 and odds ratio of <1 for all models of genetic inheritance. CLEC4E rs10841847 genotypes in co-dominant, Recessive, Dominant models and alleles had a significant statistical difference between patients and controls associated with resistance against the development of PTB (P < 0.05 and OR < 1). Our findings suggest that variations at rs10841845 and rs10841847 of CLEC4E genes are associated with increased individual protection against PTB." @default.
• W2944599913 created "2019-05-16" @default.
• W2944599913 creator A5028936906 @default.
• W2944599913 creator A5037305252 @default.
• W2944599913 creator A5063580034 @default.
• W2944599913 creator A5065370071 @default.
• W2944599913 creator A5070617202 @default.
• W2944599913 date "2019-08-01" @default.
• W2944599913 modified "2023-10-14" @default.
• W2944599913 title "Association between CLEC4E gene polymorphism of mincle and pulmonary tuberculosis infection in a northern Chinese population" @default.
• W2944599913 cites W1735091417 @default.
• W2944599913 cites W1967305091 @default.
• W2944599913 cites W1984561776 @default.
• W2944599913 cites W2002680664 @default.
• W2944599913 cites W2005183346 @default.
• W2944599913 cites W2026073975 @default.
• W2944599913 cites W2039415527 @default.
• W2944599913 cites W2042891903 @default.
• W2944599913 cites W2043644613 @default.
• W2944599913 cites W2054574453 @default.
• W2944599913 cites W2059122129 @default.
• W2944599913 cites W2078493033 @default.
• W2944599913 cites W2102609957 @default.
• W2944599913 cites W2106248075 @default.
• W2944599913 cites W2123921145 @default.
• W2944599913 cites W2132914503 @default.
• W2944599913 cites W2143796251 @default.
• W2944599913 cites W2148215656 @default.
• W2944599913 cites W2153548587 @default.
• W2944599913 cites W2158349290 @default.
• W2944599913 cites W2165523585 @default.
• W2944599913 cites W217408579 @default.
• W2944599913 cites W2239399748 @default.
• W2944599913 cites W2259720540 @default.
• W2944599913 cites W2264731258 @default.
• W2944599913 cites W2407241366 @default.
• W2944599913 cites W2475056214 @default.
• W2944599913 cites W2501401121 @default.
• W2944599913 cites W2520411544 @default.
• W2944599913 cites W2560674140 @default.
• W2944599913 cites W2575666654 @default.
• W2944599913 cites W2577011855 @default.
• W2944599913 cites W2580334607 @default.
• W2944599913 cites W2593431602 @default.
• W2944599913 cites W2595584585 @default.
• W2944599913 cites W2681515585 @default.
• W2944599913 cites W2731763120 @default.
• W2944599913 cites W2738221154 @default.
• W2944599913 cites W2767100042 @default.
• W2944599913 cites W2791597484 @default.
• W2944599913 cites W2800181679 @default.
• W2944599913 cites W2895937750 @default.
• W2944599913 cites W2913062994 @default.
• W2944599913 doi "https://doi.org/10.1016/j.gene.2019.05.011" @default.
• W2944599913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31075410" @default.
• W2944599913 hasPublicationYear "2019" @default.
• W2944599913 type Work @default.
• W2944599913 sameAs 2944599913 @default.
• W2944599913 citedByCount "11" @default.
• W2944599913 countsByYear W29445999132020 @default.
• W2944599913 countsByYear W29445999132021 @default.
• W2944599913 countsByYear W29445999132022 @default.
• W2944599913 countsByYear W29445999132023 @default.
• W2944599913 crossrefType "journal-article" @default.
• W2944599913 hasAuthorship W2944599913A5028936906 @default.
• W2944599913 hasAuthorship W2944599913A5037305252 @default.
• W2944599913 hasAuthorship W2944599913A5063580034 @default.
• W2944599913 hasAuthorship W2944599913A5065370071 @default.
• W2944599913 hasAuthorship W2944599913A5070617202 @default.
• W2944599913 hasConcept C104317684 @default.
• W2944599913 hasConcept C126322002 @default.
• W2944599913 hasConcept C135763542 @default.
• W2944599913 hasConcept C142724271 @default.
• W2944599913 hasConcept C153209595 @default.
• W2944599913 hasConcept C156957248 @default.
• W2944599913 hasConcept C180754005 @default.
• W2944599913 hasConcept C203014093 @default.
• W2944599913 hasConcept C2777975735 @default.
• W2944599913 hasConcept C2781069245 @default.
• W2944599913 hasConcept C2908647359 @default.
• W2944599913 hasConcept C54355233 @default.
• W2944599913 hasConcept C71924100 @default.
• W2944599913 hasConcept C86803240 @default.
• W2944599913 hasConcept C99454951 @default.
• W2944599913 hasConceptScore W2944599913C104317684 @default.
• W2944599913 hasConceptScore W2944599913C126322002 @default.
• W2944599913 hasConceptScore W2944599913C135763542 @default.
• W2944599913 hasConceptScore W2944599913C142724271 @default.
• W2944599913 hasConceptScore W2944599913C153209595 @default.
• W2944599913 hasConceptScore W2944599913C156957248 @default.
• W2944599913 hasConceptScore W2944599913C180754005 @default.
• W2944599913 hasConceptScore W2944599913C203014093 @default.
• W2944599913 hasConceptScore W2944599913C2777975735 @default.
• W2944599913 hasConceptScore W2944599913C2781069245 @default.
• W2944599913 hasConceptScore W2944599913C2908647359 @default.
• W2944599913 hasConceptScore W2944599913C54355233 @default.
• W2944599913 hasConceptScore W2944599913C71924100 @default.
• W2944599913 hasConceptScore W2944599913C86803240 @default.

• next