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• W2944652200 abstract "Vascular aging is an independent risk factor for cardiovascular diseases, which has always been a research hotspot. This study aims to establish a Multiple Linear Regression (MLR) model using radial artery pulse wave characteristic parameters to assess vascular aging. Data from 111 males and 117 females were used to propose a new method for extracting pulse wave characteristic parameters called, Equal Pressure Pulse Transit Time (EP-PTT). Firstly, 10 EP-PTTs were extracted from pulse waves which were used to describe the shape characteristics of the pulse signal. Secondly, 10 EP-PTTs were fed into MLR model, which were used to optimize the model. Lastly, the predicted age of all subjects was calculated by the optimal model. We compared the correlation coefficients of predicted age with Pulse Transit Time (PTT) and Augmentation Index (AIx) with the correlation coefficients of chronological age with PTT and AIx. 9 EP-PTTs were relevant to predicting age in men and all EP-PTTs were age-related in women (P<0.05). MLR analysis showed that EP-PTT3 and EP-PTT7 were potent predictors of vascular age in men but EP-PTT4 and EP-PTT7 were important predictors in women (P<0.001). Comparing with the chronological age, the predicted age was closer to PTT (P<0.001, r=-0.53 to P<0.001, r=-0.59 in men; P<0.001, r=-0.57 to P<0.001, r=-0.65 in women) and AIx (P<0.001, r=0.64 to P<0.001, r=0.81 in men; P<0.001, r=0.51 to P<0.001, r=0.56 in women). The predicted age can better reflect vascular aging than chronological age. This proved the validity of the proposed method for assessing vascular aging." @default.
• W2944652200 created "2019-05-16" @default.
• W2944652200 creator A5005385852 @default.
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• W2944652200 date "2019-06-01" @default.
• W2944652200 modified "2023-09-24" @default.
• W2944652200 title "Multiple linear regression model for vascular aging assessment based on radial artery pulse wave" @default.
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• W2944652200 doi "https://doi.org/10.1016/j.eujim.2019.05.006" @default.
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