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- W2944773024 endingPage "34" @default.
- W2944773024 startingPage "34" @default.
- W2944773024 abstract "Genetic mitochondrial cardiomyopathies are uncommon causes of heart failure that may not be seen by most physicians. However, the prevalence of mitochondrial DNA mutations and somatic mutations affecting mitochondrial function are more common than previously thought. In this review, the pathogenesis of genetic mitochondrial disorders causing cardiovascular disease is reviewed. Treatment options are presently limited to mostly symptomatic support, but preclinical research is starting to reveal novel approaches that may lead to better and more targeted therapies in the future. With better understanding and clinician education, we hope to improve clinician recognition and diagnosis of these rare disorders in order to improve ongoing care of patients with these diseases and advance research towards discovering new therapeutic strategies to help treat these diseases." @default.
- W2944773024 created "2019-05-16" @default.
- W2944773024 creator A5013936660 @default.
- W2944773024 creator A5015792539 @default.
- W2944773024 creator A5047112099 @default.
- W2944773024 date "2019-05-11" @default.
- W2944773024 modified "2023-10-03" @default.
- W2944773024 title "Cardiovascular Manifestations of Mitochondrial Disease" @default.
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