FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2944784306> ?p ?o ?g. }

• W2944784306 abstract "Background: Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer 2018 state that sentinel lymph node (SN) biopsy is unnecessary for patients treated with breast-conserving therapy (BCT) and with an expected final pathological diagnosis of ductal carcinoma in situ (DCIS). Regardless of whether they were diagnosed with DCIS by biopsy before surgery, 78% of patients currently undergo axial procedures in Japan because invasive lesions may be detected in surgical specimens. This study examined whether SN biopsy can be omitted in DCIS patients diagnosed by biopsy and which factors are associated with invasion. Methods: Patients who underwent definitive surgery for DCIS diagnosed by preoperative biopsy at our institution from May 2004 to January 2018 were investigated retrospectively. The factors associated with upstaging to invasive cancer from DCIS were examined with Fisher9s exact test and the t-test. (Age, Tumor size, Operation (Mastectomy or BCT), Biopsy method (Core Needle Biopsy or Vaccume-Assisted Biopsy), Mammography (ditected or not-detected), Ultrasound (ditected or not-detected, mass or non-mass), Comedo, ER, PgR, HER2) Results: A total of 311 patients were enrolled in this study, of whom 277 (89.1%) underwent SN; six of these (2.2%) had SN metastasis. All six cases were upstaging to invasive cancer: five (1.8%) had micrometastasis and one had macrometastasis (0.4%). From a surgical viewpoint, SN metastasis were detected in 3/161 (1.9%) cases treated with mastectomy and 3/150 (2.4%) cases treated with BCT. Although all three cases treated with BCT had micrometastasis, one case treated with mastectomy had macrometastasis (the other two cases had micrometatastasis). A total of 80/311 cases (25.7%) upstaged to invasive cancer and the only predictor of invasion was tumor size on images (p=0.0002). We could not determine the effective cut-off for tumor size because the area under the receiver operating characteristic curve was 0.63 Conclusion: Tumor size was found to be the only predictor of invasion. Only 2.2% of DCIS patients had SN metastasis despite the fact that 25.7% patients were upstaged to invasive cancer. We conclude that SN biopsy is not necessary for DCIS patients diagnosed by biopsy. Citation Format: Uemoto Y, Kondo N, Wanifuchi-Endo Y, Hisada T, Nishikawa S, Katagiri Y, Kato H, Takahashi S, Toyama T. Sentinel lymph node biopsy is unnecessary in ductal carcinoma in situ patients diagnosed by biopsy [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2019;79(4 Suppl):Abstract nr P3-03-34." @default.
• W2944784306 created "2019-05-16" @default.
• W2944784306 creator A5001406398 @default.
• W2944784306 creator A5011041663 @default.
• W2944784306 creator A5027634537 @default.
• W2944784306 creator A5044442237 @default.
• W2944784306 creator A5045086285 @default.
• W2944784306 creator A5058875319 @default.
• W2944784306 creator A5065031449 @default.
• W2944784306 creator A5079170092 @default.
• W2944784306 creator A5091178168 @default.
• W2944784306 date "2019-02-15" @default.
• W2944784306 modified "2023-09-27" @default.
• W2944784306 title "Abstract P3-03-34: Sentinel lymph node biopsy is unnecessary in ductal carcinomain situpatients diagnosed by biopsy" @default.
• W2944784306 doi "https://doi.org/10.1158/1538-7445.sabcs18-p3-03-34" @default.
• W2944784306 hasPublicationYear "2019" @default.
• W2944784306 type Work @default.
• W2944784306 sameAs 2944784306 @default.
• W2944784306 citedByCount "0" @default.
• W2944784306 crossrefType "proceedings-article" @default.
• W2944784306 hasAuthorship W2944784306A5001406398 @default.
• W2944784306 hasAuthorship W2944784306A5011041663 @default.
• W2944784306 hasAuthorship W2944784306A5027634537 @default.
• W2944784306 hasAuthorship W2944784306A5044442237 @default.
• W2944784306 hasAuthorship W2944784306A5045086285 @default.
• W2944784306 hasAuthorship W2944784306A5058875319 @default.
• W2944784306 hasAuthorship W2944784306A5065031449 @default.
• W2944784306 hasAuthorship W2944784306A5079170092 @default.
• W2944784306 hasAuthorship W2944784306A5091178168 @default.
• W2944784306 hasConcept C121608353 @default.
• W2944784306 hasConcept C126322002 @default.
• W2944784306 hasConcept C126838900 @default.
• W2944784306 hasConcept C141071460 @default.
• W2944784306 hasConcept C2775934546 @default.
• W2944784306 hasConcept C2777757722 @default.
• W2944784306 hasConcept C2778123414 @default.
• W2944784306 hasConcept C2779013556 @default.
• W2944784306 hasConcept C2780212769 @default.
• W2944784306 hasConcept C2780472235 @default.
• W2944784306 hasConcept C2780862961 @default.
• W2944784306 hasConcept C530470458 @default.
• W2944784306 hasConcept C71924100 @default.
• W2944784306 hasConceptScore W2944784306C121608353 @default.
• W2944784306 hasConceptScore W2944784306C126322002 @default.
• W2944784306 hasConceptScore W2944784306C126838900 @default.
• W2944784306 hasConceptScore W2944784306C141071460 @default.
• W2944784306 hasConceptScore W2944784306C2775934546 @default.
• W2944784306 hasConceptScore W2944784306C2777757722 @default.
• W2944784306 hasConceptScore W2944784306C2778123414 @default.
• W2944784306 hasConceptScore W2944784306C2779013556 @default.
• W2944784306 hasConceptScore W2944784306C2780212769 @default.
• W2944784306 hasConceptScore W2944784306C2780472235 @default.
• W2944784306 hasConceptScore W2944784306C2780862961 @default.
• W2944784306 hasConceptScore W2944784306C530470458 @default.
• W2944784306 hasConceptScore W2944784306C71924100 @default.
• W2944784306 hasLocation W29447843061 @default.
• W2944784306 hasOpenAccess W2944784306 @default.
• W2944784306 hasPrimaryLocation W29447843061 @default.
• W2944784306 hasRelatedWork W1887287895 @default.
• W2944784306 hasRelatedWork W1992683834 @default.
• W2944784306 hasRelatedWork W2001621317 @default.
• W2944784306 hasRelatedWork W2006054420 @default.
• W2944784306 hasRelatedWork W2024485794 @default.
• W2944784306 hasRelatedWork W2024489351 @default.
• W2944784306 hasRelatedWork W2028266208 @default.
• W2944784306 hasRelatedWork W2087097787 @default.
• W2944784306 hasRelatedWork W2087800498 @default.
• W2944784306 hasRelatedWork W2091670521 @default.
• W2944784306 hasRelatedWork W2301285481 @default.
• W2944784306 hasRelatedWork W2324391866 @default.
• W2944784306 hasRelatedWork W2325546637 @default.
• W2944784306 hasRelatedWork W2626702254 @default.
• W2944784306 hasRelatedWork W2804305296 @default.
• W2944784306 hasRelatedWork W2946909199 @default.
• W2944784306 hasRelatedWork W2964603785 @default.
• W2944784306 hasRelatedWork W3108733566 @default.
• W2944784306 hasRelatedWork W3173967801 @default.
• W2944784306 hasRelatedWork W3198640475 @default.
• W2944784306 isParatext "false" @default.
• W2944784306 isRetracted "false" @default.
• W2944784306 magId "2944784306" @default.
• W2944784306 workType "article" @default.