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• W2944799040 abstract "Introduction: The expiry of patents for biologics has led to the introduction of biosimilars for the treatment of immune-mediated inflammatory diseases (IMIDs). These treatment alternatives may allow earlier and wider access to appropriate therapy for patients without increasing the economic burden on health-care systems. Prescription of biosimilars to treatment-naïve patients is well accepted; however, additional considerations must be taken into account when switching clinically stable patients from reference products to biosimilars. Area covered: We discuss the current considerations related to switching from reference products to biosimilars from a physician and patient perspective. We review the clinical data and real-life experience on switching patients with IMIDs, present the position of the relevant medical societies, and discuss the importance of patient-physician communication and need for shared decision-making. Expert opinion: The introduction of biosimilars provides an opportunity to expand access to treatment for patients with IMIDs across Europe and support the financial sustainability of health-care systems. We anticipate that as the real-world evidence base grows, confirming the results of clinical trials, there will be a corresponding increase in physician and patient acceptance, not only to initiating treatment with a biosimilar, but also to switching medication from a reference product to a biosimilar." @default.
• W2944799040 created "2019-05-16" @default.
• W2944799040 creator A5022295471 @default.
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• W2944799040 creator A5080267247 @default.
• W2944799040 creator A5085768638 @default.
• W2944799040 date "2019-05-06" @default.
• W2944799040 modified "2023-10-16" @default.
• W2944799040 title "Switching to biosimilars: current perspectives in immune-mediated inflammatory diseases" @default.
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• W2944799040 doi "https://doi.org/10.1080/14712598.2019.1610381" @default.
• W2944799040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31056970" @default.
• W2944799040 hasPublicationYear "2019" @default.
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