FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945009602> ?p ?o ?g. }

• W2945009602 endingPage "1776" @default.
• W2945009602 startingPage "1769" @default.
• W2945009602 abstract "Objective: To compare the risk of hospitalization and costs associated with major bleeding (MB) or stroke/systemic embolism (SE) among elderly patients with nonvalvular atrial fibrillation (NVAF) who initiated apixaban then switched to another oral anticoagulant (OAC) vs. those who continued with apixaban treatment.Methods: NVAF patients (≥65 years) initiating apixaban were identified from the Humana database (1 January 2013–30 September 2017) and grouped into switcher and continuer cohorts. For switchers, the earliest switch from apixaban to another OAC was defined as the index event/date. A random date during apixaban treatment was selected as the index date for continuers. Patients were followed from index date to health plan disenrollment or 31 December 2017, whichever was earlier. Multivariable regression analyses were used to examine the association of switchers vs. continuers with risk of MB-related or stroke/SE-related hospitalization and healthcare costs during follow-up.Results: Of 7858 elderly NVAF patients included in the study, 14% (N = 1110; mean age: 78 years) were switchers; 86% (N = 6748; mean age: 79 years) were continuers. Apixaban switchers vs. continuers had significantly greater risk of MB-related hospitalization (hazard ratio [HR]: 2.00; 95% CI: 1.52–2.64; p < .001) during follow-up; risk of stroke/SE hospitalization did not differ significantly (HR: 1.36, 95% CI: 0.89–2.06, p = .154). MB- and stroke/SE-related medical costs were higher for switchers vs. continuers, although total all-cause healthcare costs were similar.Conclusion: Elderly patients with NVAF in the US who continued with apixaban treatment had a lower risk of MB-related hospitalization and lower MB- and stroke/SE-related medical costs compared to patients who switched to another OAC." @default.
• W2945009602 created "2019-05-29" @default.
• W2945009602 creator A5003433493 @default.
• W2945009602 creator A5013717649 @default.
• W2945009602 creator A5026378192 @default.
• W2945009602 creator A5040177032 @default.
• W2945009602 creator A5054571533 @default.
• W2945009602 creator A5054707936 @default.
• W2945009602 creator A5057689988 @default.
• W2945009602 creator A5080303082 @default.
• W2945009602 creator A5087610563 @default.
• W2945009602 date "2019-06-05" @default.
• W2945009602 modified "2023-09-27" @default.
• W2945009602 title "Continuation with apixaban treatment is associated with lower risk for hospitalization and medical costs among elderly patients" @default.
• W2945009602 cites W1984121983 @default.
• W2945009602 cites W2065462436 @default.
• W2945009602 cites W2066181144 @default.
• W2945009602 cites W2107020336 @default.
• W2945009602 cites W2114775432 @default.
• W2945009602 cites W2162508946 @default.
• W2945009602 cites W2170350621 @default.
• W2945009602 cites W2433454023 @default.
• W2945009602 cites W2513537003 @default.
• W2945009602 cites W2523933248 @default.
• W2945009602 cites W2595447138 @default.
• W2945009602 cites W2620376388 @default.
• W2945009602 cites W2623715034 @default.
• W2945009602 cites W2743673880 @default.
• W2945009602 cites W2771956980 @default.
• W2945009602 cites W2785163084 @default.
• W2945009602 cites W2792431841 @default.
• W2945009602 cites W2806769225 @default.
• W2945009602 cites W2810340659 @default.
• W2945009602 cites W2888989718 @default.
• W2945009602 cites W2892188073 @default.
• W2945009602 cites W2899136154 @default.
• W2945009602 cites W2904378195 @default.
• W2945009602 cites W4205645630 @default.
• W2945009602 cites W4250606563 @default.
• W2945009602 doi "https://doi.org/10.1080/03007995.2019.1623187" @default.
• W2945009602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31120309" @default.
• W2945009602 hasPublicationYear "2019" @default.
• W2945009602 type Work @default.
• W2945009602 sameAs 2945009602 @default.
• W2945009602 citedByCount "5" @default.
• W2945009602 countsByYear W29450096022019 @default.
• W2945009602 countsByYear W29450096022020 @default.
• W2945009602 countsByYear W29450096022021 @default.
• W2945009602 countsByYear W29450096022022 @default.
• W2945009602 countsByYear W29450096022023 @default.
• W2945009602 crossrefType "journal-article" @default.
• W2945009602 hasAuthorship W2945009602A5003433493 @default.
• W2945009602 hasAuthorship W2945009602A5013717649 @default.
• W2945009602 hasAuthorship W2945009602A5026378192 @default.
• W2945009602 hasAuthorship W2945009602A5040177032 @default.
• W2945009602 hasAuthorship W2945009602A5054571533 @default.
• W2945009602 hasAuthorship W2945009602A5054707936 @default.
• W2945009602 hasAuthorship W2945009602A5057689988 @default.
• W2945009602 hasAuthorship W2945009602A5080303082 @default.
• W2945009602 hasAuthorship W2945009602A5087610563 @default.
• W2945009602 hasConcept C126322002 @default.
• W2945009602 hasConcept C127413603 @default.
• W2945009602 hasConcept C1862650 @default.
• W2945009602 hasConcept C194828623 @default.
• W2945009602 hasConcept C207103383 @default.
• W2945009602 hasConcept C2776301958 @default.
• W2945009602 hasConcept C2778661090 @default.
• W2945009602 hasConcept C2779161974 @default.
• W2945009602 hasConcept C2780638905 @default.
• W2945009602 hasConcept C2780645631 @default.
• W2945009602 hasConcept C44249647 @default.
• W2945009602 hasConcept C71924100 @default.
• W2945009602 hasConcept C78519656 @default.
• W2945009602 hasConceptScore W2945009602C126322002 @default.
• W2945009602 hasConceptScore W2945009602C127413603 @default.
• W2945009602 hasConceptScore W2945009602C1862650 @default.
• W2945009602 hasConceptScore W2945009602C194828623 @default.
• W2945009602 hasConceptScore W2945009602C207103383 @default.
• W2945009602 hasConceptScore W2945009602C2776301958 @default.
• W2945009602 hasConceptScore W2945009602C2778661090 @default.
• W2945009602 hasConceptScore W2945009602C2779161974 @default.
• W2945009602 hasConceptScore W2945009602C2780638905 @default.
• W2945009602 hasConceptScore W2945009602C2780645631 @default.
• W2945009602 hasConceptScore W2945009602C44249647 @default.
• W2945009602 hasConceptScore W2945009602C71924100 @default.
• W2945009602 hasConceptScore W2945009602C78519656 @default.
• W2945009602 hasFunder F4320307765 @default.
• W2945009602 hasIssue "10" @default.
• W2945009602 hasLocation W29450096021 @default.
• W2945009602 hasLocation W29450096022 @default.
• W2945009602 hasOpenAccess W2945009602 @default.
• W2945009602 hasPrimaryLocation W29450096021 @default.
• W2945009602 hasRelatedWork W1156521740 @default.
• W2945009602 hasRelatedWork W1992076253 @default.
• W2945009602 hasRelatedWork W1993190469 @default.
• W2945009602 hasRelatedWork W2174666533 @default.
• W2945009602 hasRelatedWork W2567468616 @default.
• W2945009602 hasRelatedWork W2797029614 @default.

• next