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- W2945094610 endingPage "2043" @default.
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- W2945094610 abstract "Extending (i.e., generalizing or transporting) causal inferences from a randomized trial to a target population requires assumptions that randomized and nonrandomized individuals are exchangeable conditional on baseline covariates. These assumptions are made on the basis of background knowledge, which is often uncertain or controversial, and need to be subjected to sensitivity analysis. We present simple methods for sensitivity analyses that directly parameterize violations of the assumptions using bias functions and do not require detailed background knowledge about specific unknown or unmeasured determinants of the outcome or modifiers of the treatment effect. We show how the methods can be applied to non‐nested trial designs, where the trial data are combined with a separately obtained sample of nonrandomized individuals, as well as to nested trial designs, where the trial is embedded within a cohort sampled from the target population." @default.
- W2945094610 created "2019-05-29" @default.
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- W2945094610 date "2023-02-27" @default.
- W2945094610 modified "2023-10-17" @default.
- W2945094610 title "Sensitivity analysis using bias functions for studies extending inferences from a randomized trial to a target population" @default.
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- W2945094610 doi "https://doi.org/10.1002/sim.9550" @default.
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