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- W2945181509 abstract "Not many morphological studies have been reported regarding the human salivary main duct, especially those based on observations of the fetal salivary main duct at various developmental stages. The relationships between fetal structural development and its function, functional disorders and diseases certainly have clinical significance.In this study, we conducted a morphological observation of seven 5-9 month old human fetal sublingual caruncula, the common opening between the submandibular (Wharton's) duct and the sublingual (Bartholin's) duct. After seven specimens were removed and paraffin sections were prepared, HE and EVG staining were used for histological study of structural differences in the various developmental stages. Furthermore, anti-α-SMA staining was used to observe the distribution of the smooth muscle inside of the Wharton's duct wall.An abundance of elastic fibers were observed in the duct walls of both five and nine month old specimens with EVG staining. The smooth muscle fibers of five month old fetus were immature and were starting to distribute throughout the duct wall, whereas nine month old fetus' smooth muscle fibers were further developed and composed in layers.In this study, we confirmed that the Wharton's duct wall structure of nine month old fetuses was close to its adult structural formation, while the inner structure consisted of an ample distribution of elastic fibers and smooth muscle fibers. Based on the distribution pattern of the smooth muscle, we speculate that the Wharton's duct's opening area does not possess a sphincter-like function in the regulation of salivary flow." @default.
- W2945181509 created "2019-05-29" @default.
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- W2945181509 date "2019-09-01" @default.
- W2945181509 modified "2023-09-24" @default.
- W2945181509 title "Study of morphological structure in human fetus Wharton's duct opening area" @default.
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- W2945181509 doi "https://doi.org/10.1016/j.ijporl.2019.05.009" @default.
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