FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945237044> ?p ?o ?g. }

• W2945237044 endingPage "61" @default.
• W2945237044 startingPage "54" @default.
• W2945237044 abstract "Interventional radiology-based imaging is the preferred choice for diagnosis and therapy of many complex diseases, despite possible adverse effects of the radiation exposures. We have measured induced DNA damage and changes in gene expression in relation to entrance surface dose (ESD) in peripheral blood samples of patients (n = 51) who underwent neuro-interventional radiological procedures. The ESD values, measured by thermoluminescence dosimetry, were 4.9–273 mGy (forehead), 14–398 mGy (eyes), 8–433.3 mGy (shoulders), and 4.7–242.5 mGy (thyroid). The in-built recorded Dose Area Product (DAP) values were 74.61–558.55 and 13.17–2825.12 Gy*cm2 for diagnostic and therapeutic procedures, respectively. The mean fluorescence intensity (MFI) on the phosphorylation of γ-H2AX and p53ser−15 was higher in samples obtained post-exposure vs. pre-exposure. However, the increase was statistically significant only for p53ser−15 (P < 0.01). Consistent with γ-H2AX, CDKN1A, FDXR, BAX, DDB2, SESN1, BCL2, MDM2, TNFSF10B, and PCNA showed (non-significant) decreased expression while GADD45A, ATM, and TNFSF9 showed (non-significant) increased expression. Our results suggest that most of the patients had increased DNA damage and altered gene expression after receiving relatively low doses of ionising radiation. This implies that these procedures should be carried out at the lowest possible doses of radiation that do not compromise image quality." @default.
• W2945237044 created "2019-05-29" @default.
• W2945237044 creator A5014793784 @default.
• W2945237044 creator A5036905367 @default.
• W2945237044 creator A5038361642 @default.
• W2945237044 creator A5071538966 @default.
• W2945237044 creator A5072306117 @default.
• W2945237044 creator A5081155426 @default.
• W2945237044 date "2019-08-01" @default.
• W2945237044 modified "2023-10-01" @default.
• W2945237044 title "DNA damage and gene expression changes in patients exposed to low-dose X-radiation during neuro-interventional radiology procedures" @default.
• W2945237044 cites W1856519150 @default.
• W2945237044 cites W1998446156 @default.
• W2945237044 cites W2014891697 @default.
• W2945237044 cites W2024639260 @default.
• W2945237044 cites W2042499074 @default.
• W2945237044 cites W2043964768 @default.
• W2945237044 cites W2062018774 @default.
• W2945237044 cites W2063433578 @default.
• W2945237044 cites W2066821059 @default.
• W2945237044 cites W2069628816 @default.
• W2945237044 cites W2073137689 @default.
• W2945237044 cites W2084969545 @default.
• W2945237044 cites W2089028776 @default.
• W2945237044 cites W2099142769 @default.
• W2945237044 cites W2102752109 @default.
• W2945237044 cites W2108205507 @default.
• W2945237044 cites W2114719365 @default.
• W2945237044 cites W2117137768 @default.
• W2945237044 cites W2124142827 @default.
• W2945237044 cites W2125264364 @default.
• W2945237044 cites W2129705418 @default.
• W2945237044 cites W2145200068 @default.
• W2945237044 cites W2162553051 @default.
• W2945237044 cites W2172017118 @default.
• W2945237044 cites W2255244472 @default.
• W2945237044 cites W2336014703 @default.
• W2945237044 cites W2409406329 @default.
• W2945237044 cites W2519821782 @default.
• W2945237044 cites W2572578245 @default.
• W2945237044 cites W2577981729 @default.
• W2945237044 cites W2604143922 @default.
• W2945237044 cites W2728865991 @default.
• W2945237044 cites W2783600734 @default.
• W2945237044 cites W4230963721 @default.
• W2945237044 doi "https://doi.org/10.1016/j.mrgentox.2019.05.011" @default.
• W2945237044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31326035" @default.
• W2945237044 hasPublicationYear "2019" @default.
• W2945237044 type Work @default.
• W2945237044 sameAs 2945237044 @default.
• W2945237044 citedByCount "18" @default.
• W2945237044 countsByYear W29452370442019 @default.
• W2945237044 countsByYear W29452370442020 @default.
• W2945237044 countsByYear W29452370442021 @default.
• W2945237044 countsByYear W29452370442022 @default.
• W2945237044 countsByYear W29452370442023 @default.
• W2945237044 crossrefType "journal-article" @default.
• W2945237044 hasAuthorship W2945237044A5014793784 @default.
• W2945237044 hasAuthorship W2945237044A5036905367 @default.
• W2945237044 hasAuthorship W2945237044A5038361642 @default.
• W2945237044 hasAuthorship W2945237044A5071538966 @default.
• W2945237044 hasAuthorship W2945237044A5072306117 @default.
• W2945237044 hasAuthorship W2945237044A5081155426 @default.
• W2945237044 hasConcept C105636585 @default.
• W2945237044 hasConcept C111337013 @default.
• W2945237044 hasConcept C121332964 @default.
• W2945237044 hasConcept C126838900 @default.
• W2945237044 hasConcept C143425029 @default.
• W2945237044 hasConcept C148325268 @default.
• W2945237044 hasConcept C18231593 @default.
• W2945237044 hasConcept C185544564 @default.
• W2945237044 hasConcept C2780353417 @default.
• W2945237044 hasConcept C2989005 @default.
• W2945237044 hasConcept C54355233 @default.
• W2945237044 hasConcept C552990157 @default.
• W2945237044 hasConcept C71924100 @default.
• W2945237044 hasConcept C75088862 @default.
• W2945237044 hasConcept C86803240 @default.
• W2945237044 hasConceptScore W2945237044C105636585 @default.
• W2945237044 hasConceptScore W2945237044C111337013 @default.
• W2945237044 hasConceptScore W2945237044C121332964 @default.
• W2945237044 hasConceptScore W2945237044C126838900 @default.
• W2945237044 hasConceptScore W2945237044C143425029 @default.
• W2945237044 hasConceptScore W2945237044C148325268 @default.
• W2945237044 hasConceptScore W2945237044C18231593 @default.
• W2945237044 hasConceptScore W2945237044C185544564 @default.
• W2945237044 hasConceptScore W2945237044C2780353417 @default.
• W2945237044 hasConceptScore W2945237044C2989005 @default.
• W2945237044 hasConceptScore W2945237044C54355233 @default.
• W2945237044 hasConceptScore W2945237044C552990157 @default.
• W2945237044 hasConceptScore W2945237044C71924100 @default.
• W2945237044 hasConceptScore W2945237044C75088862 @default.
• W2945237044 hasConceptScore W2945237044C86803240 @default.
• W2945237044 hasFunder F4320326716 @default.
• W2945237044 hasLocation W29452370441 @default.
• W2945237044 hasOpenAccess W2945237044 @default.
• W2945237044 hasPrimaryLocation W29452370441 @default.
• W2945237044 hasRelatedWork W168483903 @default.

• next