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- W2945248352 abstract "BPNSTs and MPNSTs in the upper extremity can occur as solitary or as syndrome-related lesions. Classically, Tinel sign is positive over the tumor. Clinical features of rapid growth, new neuro- logic symptoms, and increased pain are suggestive of but not specific for malignant transformation. Radiological evaluation with MRI can provide diagnostic information in 75% of cases and 18F FDG-PET/CT may be used to help differentiate benign from malignant lesions, with an SUV greater than 4.0 suggestive of malignant lesions. Treatment in the upper extremity is with surgical excision. Intraneural dissection is recommended for all schwannomas and many neurofibromas, although some degree of fascicular sacrifice may be necessary and the degree of excision should be tailored to the nerve involved. MPNSTs have a poor prognosis and require multidisciplinary care and a wide surgical excision, which may lead to amputation." @default.
- W2945248352 created "2019-05-29" @default.
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- W2945248352 date "2019-07-01" @default.
- W2945248352 modified "2023-10-15" @default.
- W2945248352 title "Nerve Tumors of the Upper Extremity" @default.
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- W2945248352 doi "https://doi.org/10.1016/j.cps.2019.02.008" @default.
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