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- W2945249969 abstract "The oral pathology treatment against the background of somatic diseases is important problem of modern dentistry. It is known that negative drug effects of somatic diseases basic therapy have different clinical manifestations in the oral cavity and depend on the route of administration, dose, duration of use. Adverse systemic drugs effects are quite various, however some of them are more prevalent than others, and manifest themselves as influence on saliva and salivary glands, oral mucosa and hard dental tissues. Therefore, the use of local treatment in the oral cavity is important for correction of these changes.Objective — to improve the properties of oral fluid in patients with chronic obstructive pulmonary disease (COPD) comorbid with coronary heart disease (CHD) with the usage of local therapy in the oral cavity.Materials and methods. The clinical dental study has been performed with involvement of 25 patients in the main group and 24 patients of the observation group, administered the basic therapy for COPD comorbid with CHD. The examinations have been performed for the physical properties of oral fluid (salivation rate, viscosity and pH) at the first visit and 6 months after beginning of local oral therapy.Results and discussion. The comparison of complaints and physical parameters of oral fluid in the beginning of the study and 6 months later demonstrated the decrease of dental complaints frequency, significant increase of salivation, and decrease of oral fluid viscosity in patients who adhered the prescribed therapy. These results demonstrate the high efficacy of local treatment program for the oral cavity. Conclusions. The medicines-induced pathomorphosis, caused by the simultaneous use of several drugs with xerogenic effects, proved to be a very significant factor of changes in the oral fluid of the examined patients." @default.
- W2945249969 created "2019-05-29" @default.
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- W2945249969 date "2019-03-19" @default.
- W2945249969 modified "2023-09-25" @default.
- W2945249969 title "Correction of indicators of oral fluid in patients with bronchocardial pathology" @default.
- W2945249969 doi "https://doi.org/10.30978/utj2019-1-70" @default.
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