FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945261657> ?p ?o ?g. }

• W2945261657 abstract "Biotin is widely available over the counter in different doses and is used medically in the management of hair and nail problems. Recent literature suggested the use of high doses of biotin for the treatment of progressive multiple sclerosis. We present four cases that show a misleading increase in thyroid function tests toward a false diagnosis of Grave's disease after the administration of 20-30 mg biotin for different periods. All the four cases are free of the signs and symptoms of hyperthyroidism, and all of their results returned to baseline values within 24-48 hours after biotin withdrawal. The assemblage of these cases, thyroid assay results, and biotin doses had occurred by chance, with no selection bias, and they represented all cases of biotin interference with thyroid assays in our center during this year. The first case is a 23-year-old female who was diagnosed with Grave's disease during a routine checkup after she ingested a prescribed 20 mg biotin per day for three months for excessive hair fall. The second case is a 19-year-old female with hair and nail problems associated with iron deficiency anemia. She administered a self-prescribed biotin dose of 20 mg a day for a month. She asked an endocrinologist's opinion about a recent increase in her thyroid function tests, with no signs of hyperthyroidism. The third case is a 45-year-old man with near-total thyroidectomy for retrosternal multinodular goiter with compressive symptoms. His usual levothyroxine dose had been decreased from 100 to 50 microgram per day, after which he felt unwell and gained four kilograms, with signs and symptoms of hypothyroidism. His investigations were consistent with hyperthyroidism while his signs were of hypothyroidism, which was illogical. He was administered 30 mg medically prescribed biotin for nail changes due to recently diagnosed psoriasis. The fourth case is that of one of the authors who volunteered to take 30 mg of biotin daily for one week. His initial investigations were in the normal range but changed within this period to be Grave's disease-like, with no signs or symptoms. In conclusion, the ingestion of 20 mg or more of biotin may lead to a clinically relevant thyroid assay interference. The clinicians must take this point in consideration before assessing the results of any thyroid function tests." @default.
• W2945261657 created "2019-05-29" @default.
• W2945261657 creator A5023101101 @default.
• W2945261657 creator A5040244244 @default.
• W2945261657 creator A5052416846 @default.
• W2945261657 date "2019-05-23" @default.
• W2945261657 modified "2023-10-16" @default.
• W2945261657 title "How Biotin Induces Misleading Results in Thyroid Bioassays: Case Series" @default.
• W2945261657 cites W1968513811 @default.
• W2945261657 cites W1984579435 @default.
• W2945261657 cites W2039592697 @default.
• W2945261657 cites W2145897416 @default.
• W2945261657 cites W2325763399 @default.
• W2945261657 cites W2329517480 @default.
• W2945261657 cites W2396241021 @default.
• W2945261657 cites W2426130102 @default.
• W2945261657 cites W2465645327 @default.
• W2945261657 cites W2489634309 @default.
• W2945261657 cites W2510859603 @default.
• W2945261657 cites W2516933520 @default.
• W2945261657 cites W2575112998 @default.
• W2945261657 cites W2588400230 @default.
• W2945261657 cites W2590918357 @default.
• W2945261657 cites W2607344223 @default.
• W2945261657 cites W2758889989 @default.
• W2945261657 cites W2806739298 @default.
• W2945261657 doi "https://doi.org/10.7759/cureus.4727" @default.
• W2945261657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6663274" @default.
• W2945261657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31363424" @default.
• W2945261657 hasPublicationYear "2019" @default.
• W2945261657 type Work @default.
• W2945261657 sameAs 2945261657 @default.
• W2945261657 citedByCount "5" @default.
• W2945261657 countsByYear W29452616572020 @default.
• W2945261657 countsByYear W29452616572021 @default.
• W2945261657 countsByYear W29452616572023 @default.
• W2945261657 crossrefType "journal-article" @default.
• W2945261657 hasAuthorship W2945261657A5023101101 @default.
• W2945261657 hasAuthorship W2945261657A5040244244 @default.
• W2945261657 hasAuthorship W2945261657A5052416846 @default.
• W2945261657 hasBestOaLocation W29452616571 @default.
• W2945261657 hasConcept C126322002 @default.
• W2945261657 hasConcept C141071460 @default.
• W2945261657 hasConcept C187212893 @default.
• W2945261657 hasConcept C191897082 @default.
• W2945261657 hasConcept C192562407 @default.
• W2945261657 hasConcept C2775883008 @default.
• W2945261657 hasConcept C2777074255 @default.
• W2945261657 hasConcept C2777852167 @default.
• W2945261657 hasConcept C2778204606 @default.
• W2945261657 hasConcept C2778840127 @default.
• W2945261657 hasConcept C2780176905 @default.
• W2945261657 hasConcept C2993291352 @default.
• W2945261657 hasConcept C42407357 @default.
• W2945261657 hasConcept C526584372 @default.
• W2945261657 hasConcept C54355233 @default.
• W2945261657 hasConcept C71924100 @default.
• W2945261657 hasConcept C86803240 @default.
• W2945261657 hasConcept C90924648 @default.
• W2945261657 hasConceptScore W2945261657C126322002 @default.
• W2945261657 hasConceptScore W2945261657C141071460 @default.
• W2945261657 hasConceptScore W2945261657C187212893 @default.
• W2945261657 hasConceptScore W2945261657C191897082 @default.
• W2945261657 hasConceptScore W2945261657C192562407 @default.
• W2945261657 hasConceptScore W2945261657C2775883008 @default.
• W2945261657 hasConceptScore W2945261657C2777074255 @default.
• W2945261657 hasConceptScore W2945261657C2777852167 @default.
• W2945261657 hasConceptScore W2945261657C2778204606 @default.
• W2945261657 hasConceptScore W2945261657C2778840127 @default.
• W2945261657 hasConceptScore W2945261657C2780176905 @default.
• W2945261657 hasConceptScore W2945261657C2993291352 @default.
• W2945261657 hasConceptScore W2945261657C42407357 @default.
• W2945261657 hasConceptScore W2945261657C526584372 @default.
• W2945261657 hasConceptScore W2945261657C54355233 @default.
• W2945261657 hasConceptScore W2945261657C71924100 @default.
• W2945261657 hasConceptScore W2945261657C86803240 @default.
• W2945261657 hasConceptScore W2945261657C90924648 @default.
• W2945261657 hasLocation W29452616571 @default.
• W2945261657 hasLocation W29452616572 @default.
• W2945261657 hasLocation W29452616573 @default.
• W2945261657 hasLocation W29452616574 @default.
• W2945261657 hasOpenAccess W2945261657 @default.
• W2945261657 hasPrimaryLocation W29452616571 @default.
• W2945261657 hasRelatedWork W2053394181 @default.
• W2945261657 hasRelatedWork W2067967751 @default.
• W2945261657 hasRelatedWork W2090958699 @default.
• W2945261657 hasRelatedWork W2160970338 @default.
• W2945261657 hasRelatedWork W2757575526 @default.
• W2945261657 hasRelatedWork W2945261657 @default.
• W2945261657 hasRelatedWork W3014276731 @default.
• W2945261657 hasRelatedWork W3153464026 @default.
• W2945261657 hasRelatedWork W4286493402 @default.
• W2945261657 hasRelatedWork W4318754444 @default.
• W2945261657 isParatext "false" @default.
• W2945261657 isRetracted "false" @default.
• W2945261657 magId "2945261657" @default.
• W2945261657 workType "article" @default.