FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945306737> ?p ?o ?g. }

• W2945306737 abstract "Cancer stem cells (CSCs) or tumor-initiating cells (TICs) are a population of cells present within tumor that have increased self-renewal, chemoresistance, and aggressiveness, thereby contributing to tumor relapse. Literature shows that CSCs or TICs typically originate within the hypoxic niches of the tumor, making hypoxia one of the driving factors for generation of this population. Hypoxic stress promotes adaptation to low oxygen tension in the tissues by altering metabolic properties of the CSCs. This leads to a number of altered enzymatic activities in the CSC population that further contribute to the survival of the CSCs leading to resistance to standard therapy. Hence, understanding this altered metabolic pathways as well as targeting key nodes in these may pave the way for cancer management.Glucose and glutamine are the major substrates utilized by cancer cells and feed into multiple biosynthetic pathways. Hence, labeling and tracking these compounds may reveal some novel metabolic pathways exploited by cancer stem cells to acquire survival advantage. In these current book chapters, we elaborately summarized the basic steps required for isolation, characterization, and metabolic labeling (13C6 glucose and 13C5 glutamine) of CSC for flux analysis." @default.
• W2945306737 created "2019-05-29" @default.
• W2945306737 creator A5009648827 @default.
• W2945306737 creator A5088154323 @default.
• W2945306737 date "2019-01-01" @default.
• W2945306737 modified "2023-09-26" @default.
• W2945306737 title "Labeling Cancer Stem Cells with 13C6 Glucose and 13C5 Glutamine for Metabolic Flux Analysis" @default.
• W2945306737 cites W1590478199 @default.
• W2945306737 cites W1833050134 @default.
• W2945306737 cites W1838354729 @default.
• W2945306737 cites W1897724420 @default.
• W2945306737 cites W1906647682 @default.
• W2945306737 cites W1973671455 @default.
• W2945306737 cites W1982580620 @default.
• W2945306737 cites W1983770566 @default.
• W2945306737 cites W1984413324 @default.
• W2945306737 cites W1987985161 @default.
• W2945306737 cites W1990520393 @default.
• W2945306737 cites W1997099893 @default.
• W2945306737 cites W2026579395 @default.
• W2945306737 cites W2028303721 @default.
• W2945306737 cites W2028400128 @default.
• W2945306737 cites W2031313140 @default.
• W2945306737 cites W2037961348 @default.
• W2945306737 cites W2054744694 @default.
• W2945306737 cites W2064212361 @default.
• W2945306737 cites W2066346185 @default.
• W2945306737 cites W2077841029 @default.
• W2945306737 cites W2089628226 @default.
• W2945306737 cites W2090601702 @default.
• W2945306737 cites W2129803938 @default.
• W2945306737 cites W2136909908 @default.
• W2945306737 cites W2144408907 @default.
• W2945306737 cites W2144719083 @default.
• W2945306737 cites W2261017702 @default.
• W2945306737 cites W2477699939 @default.
• W2945306737 cites W4294326454 @default.
• W2945306737 doi "https://doi.org/10.1007/978-1-4939-9488-5_18" @default.
• W2945306737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31127559" @default.
• W2945306737 hasPublicationYear "2019" @default.
• W2945306737 type Work @default.
• W2945306737 sameAs 2945306737 @default.
• W2945306737 citedByCount "0" @default.
• W2945306737 crossrefType "book-chapter" @default.
• W2945306737 hasAuthorship W2945306737A5009648827 @default.
• W2945306737 hasAuthorship W2945306737A5088154323 @default.
• W2945306737 hasConcept C121608353 @default.
• W2945306737 hasConcept C1491633281 @default.
• W2945306737 hasConcept C178790620 @default.
• W2945306737 hasConcept C185592680 @default.
• W2945306737 hasConcept C2779349466 @default.
• W2945306737 hasConcept C2780932548 @default.
• W2945306737 hasConcept C28328180 @default.
• W2945306737 hasConcept C2908647359 @default.
• W2945306737 hasConcept C502942594 @default.
• W2945306737 hasConcept C515207424 @default.
• W2945306737 hasConcept C540031477 @default.
• W2945306737 hasConcept C54355233 @default.
• W2945306737 hasConcept C55427017 @default.
• W2945306737 hasConcept C55493867 @default.
• W2945306737 hasConcept C68709404 @default.
• W2945306737 hasConcept C71924100 @default.
• W2945306737 hasConcept C7836513 @default.
• W2945306737 hasConcept C86803240 @default.
• W2945306737 hasConcept C95444343 @default.
• W2945306737 hasConcept C96232424 @default.
• W2945306737 hasConcept C99454951 @default.
• W2945306737 hasConceptScore W2945306737C121608353 @default.
• W2945306737 hasConceptScore W2945306737C1491633281 @default.
• W2945306737 hasConceptScore W2945306737C178790620 @default.
• W2945306737 hasConceptScore W2945306737C185592680 @default.
• W2945306737 hasConceptScore W2945306737C2779349466 @default.
• W2945306737 hasConceptScore W2945306737C2780932548 @default.
• W2945306737 hasConceptScore W2945306737C28328180 @default.
• W2945306737 hasConceptScore W2945306737C2908647359 @default.
• W2945306737 hasConceptScore W2945306737C502942594 @default.
• W2945306737 hasConceptScore W2945306737C515207424 @default.
• W2945306737 hasConceptScore W2945306737C540031477 @default.
• W2945306737 hasConceptScore W2945306737C54355233 @default.
• W2945306737 hasConceptScore W2945306737C55427017 @default.
• W2945306737 hasConceptScore W2945306737C55493867 @default.
• W2945306737 hasConceptScore W2945306737C68709404 @default.
• W2945306737 hasConceptScore W2945306737C71924100 @default.
• W2945306737 hasConceptScore W2945306737C7836513 @default.
• W2945306737 hasConceptScore W2945306737C86803240 @default.
• W2945306737 hasConceptScore W2945306737C95444343 @default.
• W2945306737 hasConceptScore W2945306737C96232424 @default.
• W2945306737 hasConceptScore W2945306737C99454951 @default.
• W2945306737 hasLocation W29453067371 @default.
• W2945306737 hasLocation W29453067372 @default.
• W2945306737 hasOpenAccess W2945306737 @default.
• W2945306737 hasPrimaryLocation W29453067371 @default.
• W2945306737 hasRelatedWork W170960211 @default.
• W2945306737 hasRelatedWork W1986030763 @default.
• W2945306737 hasRelatedWork W2013148168 @default.
• W2945306737 hasRelatedWork W2048296736 @default.
• W2945306737 hasRelatedWork W2343191660 @default.
• W2945306737 hasRelatedWork W2560113976 @default.
• W2945306737 hasRelatedWork W2601778356 @default.
• W2945306737 hasRelatedWork W2741545625 @default.

• next