FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945306783> ?p ?o ?g. }

• W2945306783 endingPage "494" @default.
• W2945306783 startingPage "488" @default.
• W2945306783 abstract "ABSTRACT Objective Although a reduction in brain-derived neurotrophic factor (BDNF) has been implicated as a cause of cognitive impairment in type 2 diabetes mellitus (T2DM), the role of sex in moderating this effect has not been explored. Methods We compared the difference in serum BDNF and performance on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) between 96 men and 134 women with T2DM. We compared this with the difference in serum BDNF and performance in the control group (104 men, 144 women). Results Patients with T2DM performed worse on most RBANS indices (η 2 = 0.372, all p < .05); within T2DM patients, men performed worse than women on the delayed memory score (74.1 (12.1) versus 79.9 (11.5), p = .002) and on the total score (71.4 (11.5) versus 76.5 (10.8), p = .025). Serum BDNF was lower in patients with T2DM versus controls (7.5 (2.7) ng/ml versus 11.5 (2.7) ng/ml, p < .001), and in men compared with women (6.9 (2.4) versus 7.9 (2.8), p = .024). Serum BDNF levels positively correlated with delayed memory score in patients with T2DM (β = 0.19, p = .007). However, this association was only observed in women, not in men ( p interaction = 0.04). Among healthy controls, no sex differences were noted in either RBANS or BDNF levels (η 2 = 0.04, Cohen's d < 0.163, all p > .05). Conclusions Our results show sex differences in poorer cognitive performance, lower BDNF concentration, and their relationship in T2DM patients, suggesting that female sex may be a protective factor for cognitive decline in T2DM patients. However, the findings should be regarded as preliminary because of the cross-sectional design and chronicity of the diabetes." @default.
• W2945306783 created "2019-05-29" @default.
• W2945306783 creator A5024857338 @default.
• W2945306783 creator A5041505370 @default.
• W2945306783 creator A5043994875 @default.
• W2945306783 creator A5056489444 @default.
• W2945306783 creator A5059456777 @default.
• W2945306783 creator A5084169946 @default.
• W2945306783 date "2019-05-13" @default.
• W2945306783 modified "2023-09-30" @default.
• W2945306783 title "Association of Brain-Derived Neurotrophic Factor With Cognitive Function: An Investigation of Sex Differences in Patients With Type 2 Diabetes" @default.
• W2945306783 cites W1484497860 @default.
• W2945306783 cites W1543878734 @default.
• W2945306783 cites W1571080153 @default.
• W2945306783 cites W1592656096 @default.
• W2945306783 cites W1830540419 @default.
• W2945306783 cites W1845861085 @default.
• W2945306783 cites W1855907649 @default.
• W2945306783 cites W1955459641 @default.
• W2945306783 cites W1964884387 @default.
• W2945306783 cites W1969534686 @default.
• W2945306783 cites W1969944443 @default.
• W2945306783 cites W1971736309 @default.
• W2945306783 cites W1973798645 @default.
• W2945306783 cites W1979305117 @default.
• W2945306783 cites W1993328350 @default.
• W2945306783 cites W1993693608 @default.
• W2945306783 cites W2008582903 @default.
• W2945306783 cites W2009775232 @default.
• W2945306783 cites W2013364624 @default.
• W2945306783 cites W2017561603 @default.
• W2945306783 cites W2021262492 @default.
• W2945306783 cites W2030265072 @default.
• W2945306783 cites W2030515272 @default.
• W2945306783 cites W2030877022 @default.
• W2945306783 cites W2041702995 @default.
• W2945306783 cites W2043482366 @default.
• W2945306783 cites W205881385 @default.
• W2945306783 cites W2067155791 @default.
• W2945306783 cites W2073664337 @default.
• W2945306783 cites W2079234104 @default.
• W2945306783 cites W2084272231 @default.
• W2945306783 cites W2087436174 @default.
• W2945306783 cites W2094544368 @default.
• W2945306783 cites W2095542149 @default.
• W2945306783 cites W2095551600 @default.
• W2945306783 cites W2098178967 @default.
• W2945306783 cites W2113086193 @default.
• W2945306783 cites W2121819664 @default.
• W2945306783 cites W2124386285 @default.
• W2945306783 cites W2126265100 @default.
• W2945306783 cites W2130417276 @default.
• W2945306783 cites W2132316186 @default.
• W2945306783 cites W2132575272 @default.
• W2945306783 cites W2133831987 @default.
• W2945306783 cites W2134293572 @default.
• W2945306783 cites W2141788637 @default.
• W2945306783 cites W2152502983 @default.
• W2945306783 cites W2153669504 @default.
• W2945306783 cites W2158506678 @default.
• W2945306783 cites W2159267803 @default.
• W2945306783 cites W2161875266 @default.
• W2945306783 cites W2191310828 @default.
• W2945306783 cites W2314164298 @default.
• W2945306783 cites W2592081642 @default.
• W2945306783 cites W2606057372 @default.
• W2945306783 cites W2728203119 @default.
• W2945306783 cites W2769859411 @default.
• W2945306783 cites W2806012679 @default.
• W2945306783 cites W2807739614 @default.
• W2945306783 cites W2884326415 @default.
• W2945306783 cites W2888912790 @default.
• W2945306783 cites W31370813 @default.
• W2945306783 doi "https://doi.org/10.1097/psy.0000000000000709" @default.
• W2945306783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31083054" @default.
• W2945306783 hasPublicationYear "2019" @default.
• W2945306783 type Work @default.
• W2945306783 sameAs 2945306783 @default.
• W2945306783 citedByCount "8" @default.
• W2945306783 countsByYear W29453067832019 @default.
• W2945306783 countsByYear W29453067832020 @default.
• W2945306783 countsByYear W29453067832021 @default.
• W2945306783 countsByYear W29453067832022 @default.
• W2945306783 crossrefType "journal-article" @default.
• W2945306783 hasAuthorship W2945306783A5024857338 @default.
• W2945306783 hasAuthorship W2945306783A5041505370 @default.
• W2945306783 hasAuthorship W2945306783A5043994875 @default.
• W2945306783 hasAuthorship W2945306783A5056489444 @default.
• W2945306783 hasAuthorship W2945306783A5059456777 @default.
• W2945306783 hasAuthorship W2945306783A5084169946 @default.
• W2945306783 hasConcept C118552586 @default.
• W2945306783 hasConcept C126322002 @default.
• W2945306783 hasConcept C134018914 @default.
• W2945306783 hasConcept C14216870 @default.
• W2945306783 hasConcept C15744967 @default.
• W2945306783 hasConcept C160539049 @default.
• W2945306783 hasConcept C169900460 @default.
• W2945306783 hasConcept C170493617 @default.

• next