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• W2945387946 abstract "To compare the effects of active assisted wrist extension training, using a robotic exoskeleton (RW), with simultaneous 5 Hz (rTMS + RW) or Sham rTMS (Sham rTMS + RW) over the ipsilesional extensor carpi radialis motor cortical representation, on voluntary wrist muscle activation following stroke.The two training conditions were completed at least one week apart in 13 participants >1-year post-stroke. Voluntary wrist extensor muscle activation (motor unit (MU) recruitment thresholds and firing rate modulation in a ramp-hold handgrip task), ipsilesional corticospinal excitability (motor evoked potential [MEP] amplitude) and transcallosal inhibition were measured Pre- and Post-training.For MUs active both Pre and Post training, greater reductions in recruitment thresholds were found Post rTMS + RW training (p = 0.0001) compared to Sham rTMS + RW (p = 0.16). MU firing rate modulation increased following both training conditions (p = 0.001). Ipsilesional MEPs were elicited Pre and Post in only 5/13 participants. No significant changes were seen in ipsilesional corticospinal excitability and transcallosal inhibition measures (p > 0.05).Following a single rTMS + RW session in people >1-year post-stroke, changes were found in voluntary muscle activation of wrist extensor muscles. Alterations in ipsilesional corticospinal or interhemispheric excitability were not detected.The effects of rTMS + RW on muscle activation warrant further investigation as post-stroke rehabilitation strategy." @default.
• W2945387946 created "2019-05-29" @default.
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• W2945387946 date "2019-08-01" @default.
• W2945387946 modified "2023-09-26" @default.
• W2945387946 title "Effect of repetitive transcranial magnetic stimulation combined with robot-assisted training on wrist muscle activation post-stroke" @default.
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• W2945387946 doi "https://doi.org/10.1016/j.clinph.2019.04.712" @default.
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