Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945397612> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2945397612 abstract "Non-synaptic epileptiform activities (NSEA) are brain phenomena that involve intense neuronal activities and, consequently, change the energy metabolism responsible for the production of ATP and lactate. On the other hand, it has been observed that maneuvers of interference on mechanisms involved in metabolism can affect the epileptiform activities. The aim of the present work was to investigate, using mathematical modeling and computational simulations, the behavior of the energy metabolism responsible for the production of ATP and lactate, during NSEA. The mathematical model used to simulate NSEA describes electrochemical mechanisms of the dentate gyrus of the rat hippocampus. In this model, a mathematical description of the reactions involved in energy metabolism responsible for the production of ATP and lactate, in neurons and glial cells, was included. Investigating how neuronal and glial energy metabolism are able to maintain the level of ATP during NSEA, it was possible to interpret how it is possible to suppress NSEA by reducing the rate of glucose consumption, which characterizes the effect of ketogenic diets that have been used for the treatment of epilepsies." @default.
- W2945397612 created "2019-05-29" @default.
- W2945397612 creator A5024529604 @default.
- W2945397612 creator A5038533104 @default.
- W2945397612 creator A5040474359 @default.
- W2945397612 creator A5052053130 @default.
- W2945397612 creator A5061952910 @default.
- W2945397612 creator A5083156543 @default.
- W2945397612 date "2019-01-01" @default.
- W2945397612 modified "2023-10-18" @default.
- W2945397612 title "Energy Metabolism During Non-synaptic Epileptiform Activities—Computational Simulations" @default.
- W2945397612 cites W1978114877 @default.
- W2945397612 cites W2019203278 @default.
- W2945397612 cites W2029790055 @default.
- W2945397612 cites W2034688612 @default.
- W2945397612 cites W2066650398 @default.
- W2945397612 cites W2092635505 @default.
- W2945397612 cites W2097961247 @default.
- W2945397612 cites W2102581541 @default.
- W2945397612 cites W2126594232 @default.
- W2945397612 cites W2167750958 @default.
- W2945397612 cites W2399765058 @default.
- W2945397612 doi "https://doi.org/10.1007/978-981-13-2517-5_87" @default.
- W2945397612 hasPublicationYear "2019" @default.
- W2945397612 type Work @default.
- W2945397612 sameAs 2945397612 @default.
- W2945397612 citedByCount "1" @default.
- W2945397612 countsByYear W29453976122022 @default.
- W2945397612 crossrefType "book-chapter" @default.
- W2945397612 hasAuthorship W2945397612A5024529604 @default.
- W2945397612 hasAuthorship W2945397612A5038533104 @default.
- W2945397612 hasAuthorship W2945397612A5040474359 @default.
- W2945397612 hasAuthorship W2945397612A5052053130 @default.
- W2945397612 hasAuthorship W2945397612A5061952910 @default.
- W2945397612 hasAuthorship W2945397612A5083156543 @default.
- W2945397612 hasConcept C12554922 @default.
- W2945397612 hasConcept C134018914 @default.
- W2945397612 hasConcept C169760540 @default.
- W2945397612 hasConcept C185592680 @default.
- W2945397612 hasConcept C2776464000 @default.
- W2945397612 hasConcept C2781161787 @default.
- W2945397612 hasConcept C2986317502 @default.
- W2945397612 hasConcept C55493867 @default.
- W2945397612 hasConcept C62231903 @default.
- W2945397612 hasConcept C74254510 @default.
- W2945397612 hasConcept C86803240 @default.
- W2945397612 hasConceptScore W2945397612C12554922 @default.
- W2945397612 hasConceptScore W2945397612C134018914 @default.
- W2945397612 hasConceptScore W2945397612C169760540 @default.
- W2945397612 hasConceptScore W2945397612C185592680 @default.
- W2945397612 hasConceptScore W2945397612C2776464000 @default.
- W2945397612 hasConceptScore W2945397612C2781161787 @default.
- W2945397612 hasConceptScore W2945397612C2986317502 @default.
- W2945397612 hasConceptScore W2945397612C55493867 @default.
- W2945397612 hasConceptScore W2945397612C62231903 @default.
- W2945397612 hasConceptScore W2945397612C74254510 @default.
- W2945397612 hasConceptScore W2945397612C86803240 @default.
- W2945397612 hasLocation W29453976121 @default.
- W2945397612 hasOpenAccess W2945397612 @default.
- W2945397612 hasPrimaryLocation W29453976121 @default.
- W2945397612 hasRelatedWork W1499468620 @default.
- W2945397612 hasRelatedWork W16671885 @default.
- W2945397612 hasRelatedWork W1979782640 @default.
- W2945397612 hasRelatedWork W2025258306 @default.
- W2945397612 hasRelatedWork W2050010888 @default.
- W2945397612 hasRelatedWork W2062834116 @default.
- W2945397612 hasRelatedWork W2081792644 @default.
- W2945397612 hasRelatedWork W2506904724 @default.
- W2945397612 hasRelatedWork W2911721920 @default.
- W2945397612 hasRelatedWork W2963915384 @default.
- W2945397612 isParatext "false" @default.
- W2945397612 isRetracted "false" @default.
- W2945397612 magId "2945397612" @default.
- W2945397612 workType "book-chapter" @default.